ID V6Z2B3_STRAG Unreviewed; 597 AA.
AC V6Z2B3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 37.
DE RecName: Full=Beta-glucuronidase {ECO:0000256|ARBA:ARBA00016205};
DE EC=3.2.1.31 {ECO:0000256|ARBA:ARBA00012761};
GN ORFNames=SAG0136_00430 {ECO:0000313|EMBL:ESV53754.1};
OS Streptococcus agalactiae LMG 14747.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Streptococcaceae;
OC Streptococcus.
OX NCBI_TaxID=1154860 {ECO:0000313|EMBL:ESV53754.1, ECO:0000313|Proteomes:UP000018482};
RN [1] {ECO:0000313|EMBL:ESV53754.1, ECO:0000313|Proteomes:UP000018482}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=LMG 14747 {ECO:0000313|EMBL:ESV53754.1,
RC ECO:0000313|Proteomes:UP000018482};
RA Richards V.P., Durkin S.A.S., Kim M., Pavinski Bitar P.D., Stanhope M.J.,
RA Town C.D., Venter J.C.;
RL Submitted (MAY-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 2 family.
CC {ECO:0000256|ARBA:ARBA00007401, ECO:0000256|RuleBase:RU361154}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESV53754.1}.
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DR EMBL; ANQC01000006; ESV53754.1; -; Genomic_DNA.
DR AlphaFoldDB; V6Z2B3; -.
DR eggNOG; COG3250; Bacteria.
DR Proteomes; UP000018482; Unassembled WGS sequence.
DR GO; GO:0004565; F:beta-galactosidase activity; IEA:UniProtKB-EC.
DR GO; GO:0005975; P:carbohydrate metabolic process; IEA:InterPro.
DR Gene3D; 2.60.120.260; Galactose-binding domain-like; 1.
DR Gene3D; 3.20.20.80; Glycosidases; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR036156; Beta-gal/glucu_dom_sf.
DR InterPro; IPR008979; Galactose-bd-like_sf.
DR InterPro; IPR006101; Glyco_hydro_2.
DR InterPro; IPR023232; Glyco_hydro_2_AS.
DR InterPro; IPR006103; Glyco_hydro_2_cat.
DR InterPro; IPR023230; Glyco_hydro_2_CS.
DR InterPro; IPR006102; Glyco_hydro_2_Ig-like.
DR InterPro; IPR006104; Glyco_hydro_2_N.
DR InterPro; IPR017853; Glycoside_hydrolase_SF.
DR InterPro; IPR013783; Ig-like_fold.
DR PANTHER; PTHR10066; BETA-GLUCURONIDASE; 1.
DR PANTHER; PTHR10066:SF67; BETA-GLUCURONIDASE; 1.
DR Pfam; PF00703; Glyco_hydro_2; 1.
DR Pfam; PF02836; Glyco_hydro_2_C; 1.
DR Pfam; PF02837; Glyco_hydro_2_N; 1.
DR PRINTS; PR00132; GLHYDRLASE2.
DR SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR SUPFAM; SSF49303; beta-Galactosidase/glucuronidase domain; 1.
DR SUPFAM; SSF49785; Galactose-binding domain-like; 1.
DR PROSITE; PS00719; GLYCOSYL_HYDROL_F2_1; 1.
DR PROSITE; PS00608; GLYCOSYL_HYDROL_F2_2; 1.
PE 3: Inferred from homology;
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|RuleBase:RU361154};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|RuleBase:RU361154}.
FT DOMAIN 14..177
FT /note="Glycosyl hydrolases family 2 sugar binding"
FT /evidence="ECO:0000259|Pfam:PF02837"
FT DOMAIN 179..271
FT /note="Glycoside hydrolase family 2 immunoglobulin-like
FT beta-sandwich"
FT /evidence="ECO:0000259|Pfam:PF00703"
FT DOMAIN 273..588
FT /note="Glycoside hydrolase family 2 catalytic"
FT /evidence="ECO:0000259|Pfam:PF02836"
SQ SEQUENCE 597 AA; 68880 MW; B520CD1E784B93FD CRC64;
MLYPILTKTR NVYDLNGLWN FKLGDHNPQE LLASDEVMTV PTSFNDVLVD QAKRDYIGDF
WYERFVEIPD ITKEQEAVLR FGSVTHYAKV YVNGELLGEH RGGFTPFEVL IPDHLMKESR
LKVSICANNE LNYTTLPVGN YSEELQEDGS LKKKVQENFD FFNYAGIHRP VKLVIRPKIH
LSDLVITSQL SDDMTSAVVK VDVTSSQPVD DVKVSIFDEN QQEVAVLENG QAELLDVRLW
EVLDAYLYTA HVELIKDGKV LDVYDEPFGI RSVRVADGQF FINEKPFYFK GFGKHEDTFI
NGRGLNEAAN LLDLNLLKEI GANSFRTSHY PYSEEMMRLA DRLGIVVIDE VPAVGLFHNF
HASLDGYREG NETWKRLETK AAHEQVISEL VQRDKNHPSV VMWVVANEPA SHEDGAHEYF
EPLIKLYKDL DPEKRPVTLV NIMIADPEHD KVMDLVDVIC LNRYYGWYVH HGDLKKAEEG
LRKELEDWQA LYPDKPIIMT EYGADTLPGL HSMWNIPYTE EFQIDFYDMN HKVFDEIANL
VGEQVWNFAD FETNLSILRV QGNHKGLFSR NRQPKSIVRS FKKRWDSVPN YGYKAKK
//
