ID V7AD57_PHAVU Unreviewed; 510 AA.
AC V7AD57;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Inhibitor I9 domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHAVU_011G012100g {ECO:0000313|EMBL:ESW03414.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW03414.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CM002298; ESW03414.1; -; Genomic_DNA.
DR RefSeq; XP_007131420.1; XM_007131358.1.
DR AlphaFoldDB; V7AD57; -.
DR EnsemblPlants; ESW03414; ESW03414; PHAVU_011G012100g.
DR GeneID; 18614816; -.
DR Gramene; ESW03414; ESW03414; PHAVU_011G012100g.
DR KEGG; pvu:PHAVU_011G012100g; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000000226; Chromosome 11.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF737; SUBTILISIN-LIKE PROTEASE SBT3.5 ISOFORM X1; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..32
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 33..510
FT /note="Inhibitor I9 domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004753608"
FT DOMAIN 38..117
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 142..394
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
SQ SEQUENCE 510 AA; 54865 MW; 15C966C742A7555B CRC64;
METNSRNWRW ERMAQLLAAS ALLLLQNSVA ISADTSSVHI VYMGDKIHQN PQLTKKYHNK
MLSSLLGSKE AAKSSILYSY KHGFSGFAAR LTKHQAEAIA KFPGVVSVIP NGIHKLHTTR
SWDFIGIHHS TSKSALSNSN LGEGAIIGVI DTGIWPESAS FNDEGMGQIP SRWKGVCQVG
EHFNSTNCNK KIIGARWFLK GITDQTKKLL HGNNTNEYLS ARDAIGHGTH TASTAAGNFV
GNANYRGLAS GLARGGAPLA HLAIYKACWN FPIGDCTDAD ILKAFDKAIY DGVDVLTVSL
GFSIPLFSYV DQRDVIAIGS FHATAKGITV VCSAGNSGPL SQTITNTAPW IITVGATTID
RAFPAAITLG NNLTVWGQSI DTGKHNLESV GLTYSERIAL DSSENLAKAC QSGSLNATMA
AGKIVLCFSV SDQQDIVSAS LAVKEAGGVG LVYAQYHEDG LNQCGLFPCI KVDYETGTQI
LTYIRRSSKP EFSHDCYWKM GITTSCFFLV
//
