ID V7AHL5_PHAVU Unreviewed; 956 AA.
AC V7AHL5;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 52.
DE RecName: Full=Vacuolar protein sorting-associated protein 41 homolog {ECO:0000256|ARBA:ARBA00029538, ECO:0000256|PIRNR:PIRNR028921};
GN ORFNames=PHAVU_011G088100g {ECO:0000313|EMBL:ESW04353.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW04353.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- FUNCTION: Required for vacuolar assembly and vacuolar traffic.
CC {ECO:0000256|PIRNR:PIRNR028921}.
CC -!- SUBCELLULAR LOCATION: Cytoplasmic vesicle, clathrin-coated vesicle
CC {ECO:0000256|ARBA:ARBA00004132}. Vesicle
CC {ECO:0000256|ARBA:ARBA00004373}.
CC -!- SIMILARITY: Belongs to the VPS41 family.
CC {ECO:0000256|ARBA:ARBA00009582, ECO:0000256|PIRNR:PIRNR028921}.
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DR EMBL; CM002298; ESW04353.1; -; Genomic_DNA.
DR RefSeq; XP_007132359.1; XM_007132297.1.
DR AlphaFoldDB; V7AHL5; -.
DR STRING; 3885.V7AHL5; -.
DR EnsemblPlants; ESW04353; ESW04353; PHAVU_011G088100g.
DR GeneID; 18615595; -.
DR Gramene; ESW04353; ESW04353; PHAVU_011G088100g.
DR KEGG; pvu:PHAVU_011G088100g; -.
DR eggNOG; KOG2066; Eukaryota.
DR OMA; PQLVWQD; -.
DR OrthoDB; 8838at2759; -.
DR PhylomeDB; V7AHL5; -.
DR Proteomes; UP000000226; Chromosome 11.
DR GO; GO:0030136; C:clathrin-coated vesicle; IEA:UniProtKB-SubCell.
DR GO; GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
DR GO; GO:0030897; C:HOPS complex; IEA:UniProtKB-UniRule.
DR GO; GO:0005770; C:late endosome; IEA:UniProtKB-UniRule.
DR GO; GO:0034058; P:endosomal vesicle fusion; IEA:UniProtKB-UniRule.
DR GO; GO:0006886; P:intracellular protein transport; IEA:UniProtKB-UniRule.
DR GO; GO:0006623; P:protein targeting to vacuole; IEA:InterPro.
DR GO; GO:0007034; P:vacuolar transport; IEA:UniProtKB-UniRule.
DR CDD; cd16687; RING-H2_Vps8; 1.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR000547; Clathrin_H-chain/VPS_repeat.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR016902; VPS41.
DR InterPro; IPR045111; Vps41/Vps8.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR InterPro; IPR001841; Znf_RING.
DR PANTHER; PTHR12616; VACUOLAR PROTEIN SORTING VPS41; 1.
DR PANTHER; PTHR12616:SF1; VACUOLAR PROTEIN SORTING-ASSOCIATED PROTEIN 41 HOMOLOG; 1.
DR Pfam; PF00637; Clathrin; 1.
DR PIRSF; PIRSF028921; VPS41; 2.
DR SMART; SM00299; CLH; 1.
DR SMART; SM00184; RING; 1.
DR SMART; SM00320; WD40; 2.
DR SUPFAM; SSF57850; RING/U-box; 1.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS50236; CHCR; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Protein transport {ECO:0000256|PIRNR:PIRNR028921};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Transport {ECO:0000256|PIRNR:PIRNR028921}.
FT DOMAIN 871..951
FT /note="RING-type"
FT /evidence="ECO:0000259|SMART:SM00184"
FT REGION 1..42
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 918..944
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 11..37
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 922..936
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 956 AA; 107990 MW; 4B393D105BC4BCF2 CRC64;
MAPFPSENGV EGDDEREEED EEEEEEEEEV EDEEEEEEPR LKYQRMGGSI PSLLASDAAS
CIAVAERMIA LGTHGGTVHI LDFLGNQVKE YSAHASVVND LSFDTEGEYI GSCSDDGSVV
INSLFTDEKL KFEYHRPMKA VALDPDYARK MSRRFVAGGL AGHLYLNSKK WLGYRDQVLH
SAEGSIHAVK WRASLVAWAN DAGVKVYDTA NDQRVTFIEK PRGSPRPELL LPHLVWQDDT
LLVIGWGTSV KIASIRTNHQ RAANGSFRQV PLSGVVQVDI VASFQTSYFI SGLAPFGDAL
VVLAYIPGEE DGDKDFSSSA HSRQGNAQRP EVRIVTWNND ELSTDALPVH GFEHYRAKDY
SLAHAPFSGS SYAGGQWAAG DEPLYYIVSL KDVVIAKPRD TEDHIAWLLQ HGWHEKALAV
VESGQGRSEL LDEVGSRYLD HLIVERKYSE AASLCPKLLR RSAPAWERWV FHFAHLRQLP
VLVPYMPTEN PRLRDTAYEV ALVALATNSS FHKDLLSTVK SWPSVIYSAL PVISAIEPQL
NTSSMTDSLK EALAELYVIN GQYEKAFSLY ADLMKPEVFD FIDKHNLHDA IRGKVVQLMM
LDCKRAVPLL IQNRDLISPP EAVKQLLNAD NKCDRRYFLH LYLHSLFEVN HHAGKDFHDM
QVELYAEYDP KMLLPFLRSS QHYTLEKAYE ICIKRDLLRE QVFILGRMGN SKQALAVIIN
NLGDIEEAVE FVTMQHDDEL WEELIKQCLH KPEMVGILLE HTVGNLDPLY IVNKVPNGLE
IPRLRDRLVK IITDYRTETS LRHGCNDILK ADCVNLLIKY YKEARHGVSL GNEEDEPRVK
MSDARASQVF EKSPSLRTME MKSKTRGGGR CCICFDPFSI QNVSVIVFFC CHGYHTNCLM
DSSYTSSKKK QTTSLEKEMY DDYNGYEDDA NEDSEDEETT SRGPRMRCIL CTTAAS
//
