ID V7B2J8_PHAVU Unreviewed; 424 AA.
AC V7B2J8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE RecName: Full=aldehyde dehydrogenase (NAD(+)) {ECO:0000256|ARBA:ARBA00024226};
DE EC=1.2.1.3 {ECO:0000256|ARBA:ARBA00024226};
GN ORFNames=PHAVU_009G226700g {ECO:0000313|EMBL:ESW10646.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW10646.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SUBUNIT: Homotetramer. {ECO:0000256|ARBA:ARBA00011881}.
CC -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
CC {ECO:0000256|ARBA:ARBA00009986, ECO:0000256|RuleBase:RU003345}.
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DR EMBL; CM002296; ESW10646.1; -; Genomic_DNA.
DR RefSeq; XP_007138652.1; XM_007138590.1.
DR AlphaFoldDB; V7B2J8; -.
DR STRING; 3885.V7B2J8; -.
DR EnsemblPlants; ESW10646; ESW10646; PHAVU_009G226700g.
DR GeneID; 18621007; -.
DR Gramene; ESW10646; ESW10646; PHAVU_009G226700g.
DR KEGG; pvu:PHAVU_009G226700g; -.
DR eggNOG; KOG2453; Eukaryota.
DR OMA; DAWKVYM; -.
DR OrthoDB; 8449at2759; -.
DR Proteomes; UP000000226; Chromosome 9.
DR GO; GO:0004029; F:aldehyde dehydrogenase (NAD+) activity; IEA:UniProtKB-EC.
DR GO; GO:0043878; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (non-phosphorylating) activity; IEA:UniProtKB-EC.
DR InterPro; IPR016161; Ald_DH/histidinol_DH.
DR InterPro; IPR016163; Ald_DH_C.
DR InterPro; IPR029510; Ald_DH_CS_GLU.
DR InterPro; IPR016162; Ald_DH_N.
DR InterPro; IPR015590; Aldehyde_DH_dom.
DR InterPro; IPR044638; ALDH7A1-like.
DR PANTHER; PTHR43521; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR PANTHER; PTHR43521:SF1; ALPHA-AMINOADIPIC SEMIALDEHYDE DEHYDROGENASE; 1.
DR Pfam; PF00171; Aldedh; 1.
DR SUPFAM; SSF53720; ALDH-like; 1.
DR PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE 3: Inferred from homology;
KW Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW ECO:0000256|RuleBase:RU003345};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226}.
FT DOMAIN 33..417
FT /note="Aldehyde dehydrogenase"
FT /evidence="ECO:0000259|Pfam:PF00171"
FT ACT_SITE 266
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10007"
SQ SEQUENCE 424 AA; 45453 MW; 01CFFFA8BF232633 CRC64;
MGSENNSFDF LKEIGLGSSN IGSYVNGQWK ATGSSVTSVN PSNNQTIAEV TEATLQDYEE
GLQACSEAAK TWMTIPAPKR GEIVRQIGEA LRAKLDPLGR LVALEMGKIL PEGIGEVQEI
IDMCDYAVGL SRQLSGSIIP SERPDHMMFE VWNPLGIVGV ITAFNFPCAV LGWNACIALV
CGNCVVWKGA PTTPLITIAV TKLVAEVLEK NNLPGAIFTS FCGGADIGQA IAKDTRIPLV
SFTGSTKVGL MVQQTVNDRF GKCLLELSGN NAIIVMDDAD IKLAVRSILF AAVGTAGQRC
TTCRRLFLHE SIYANVLDQL VGLYKQVKIG NPLEKGTLVG PLHTRTSVEN FQKGISVIKS
QGGKILTGGS VLESEGNFVQ PTIVEISSDA PVVKEELFGP VLYVMKFQTL EEAIALNTES
SRIK
//
