ID V7BBH4_PHAVU Unreviewed; 697 AA.
AC V7BBH4;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 46.
DE RecName: Full=Cucumisin-like {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHAVU_008G229400g {ECO:0000313|EMBL:ESW13826.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW13826.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SIMILARITY: Belongs to the peptidase S8 family.
CC {ECO:0000256|ARBA:ARBA00011073, ECO:0000256|PROSITE-ProRule:PRU01240}.
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DR EMBL; CM002295; ESW13826.1; -; Genomic_DNA.
DR RefSeq; XP_007141832.1; XM_007141770.1.
DR AlphaFoldDB; V7BBH4; -.
DR EnsemblPlants; ESW13826; ESW13826; PHAVU_008G229400g.
DR GeneID; 18623755; -.
DR Gramene; ESW13826; ESW13826; PHAVU_008G229400g.
DR KEGG; pvu:PHAVU_008G229400g; -.
DR eggNOG; ENOG502QRA7; Eukaryota.
DR OMA; AMHISAN; -.
DR OrthoDB; 11910at2759; -.
DR Proteomes; UP000000226; Chromosome 8.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR CDD; cd02120; PA_subtilisin_like; 1.
DR CDD; cd04852; Peptidases_S8_3; 1.
DR Gene3D; 2.60.40.2310; -; 1.
DR Gene3D; 3.50.30.30; -; 1.
DR Gene3D; 3.30.70.80; Peptidase S8 propeptide/proteinase inhibitor I9; 1.
DR Gene3D; 3.40.50.200; Peptidase S8/S53 domain; 1.
DR InterPro; IPR000209; Peptidase_S8/S53_dom.
DR InterPro; IPR036852; Peptidase_S8/S53_dom_sf.
DR InterPro; IPR022398; Peptidase_S8_His-AS.
DR InterPro; IPR023828; Peptidase_S8_Ser-AS.
DR InterPro; IPR015500; Peptidase_S8_subtilisin-rel.
DR InterPro; IPR034197; Peptidases_S8_3.
DR InterPro; IPR010259; S8pro/Inhibitor_I9.
DR InterPro; IPR037045; S8pro/Inhibitor_I9_sf.
DR InterPro; IPR045051; SBT.
DR InterPro; IPR041469; Subtilisin-like_FN3.
DR PANTHER; PTHR10795; PROPROTEIN CONVERTASE SUBTILISIN/KEXIN; 1.
DR PANTHER; PTHR10795:SF791; SUBTILISIN-LIKE SERINE ENDOPEPTIDASE FAMILY PROTEIN; 1.
DR Pfam; PF17766; fn3_6; 1.
DR Pfam; PF05922; Inhibitor_I9; 1.
DR Pfam; PF00082; Peptidase_S8; 1.
DR PRINTS; PR00723; SUBTILISIN.
DR SUPFAM; SSF52743; Subtilisin-like; 1.
DR PROSITE; PS51892; SUBTILASE; 1.
DR PROSITE; PS00137; SUBTILASE_HIS; 1.
DR PROSITE; PS00138; SUBTILASE_SER; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU01240};
KW Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW ProRule:PRU01240}; Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Secreted {ECO:0000256|ARBA:ARBA00022525};
KW Serine protease {ECO:0000256|ARBA:ARBA00022825, ECO:0000256|PROSITE-
KW ProRule:PRU01240}.
FT DOMAIN 13..71
FT /note="Inhibitor I9"
FT /evidence="ECO:0000259|Pfam:PF05922"
FT DOMAIN 93..540
FT /note="Peptidase S8/S53"
FT /evidence="ECO:0000259|Pfam:PF00082"
FT DOMAIN 597..694
FT /note="Subtilisin-like protease fibronectin type-III"
FT /evidence="ECO:0000259|Pfam:PF17766"
FT ACT_SITE 101
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 162
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
FT ACT_SITE 491
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR615500-1,
FT ECO:0000256|PROSITE-ProRule:PRU01240"
SQ SEQUENCE 697 AA; 74383 MW; 790DDF9DC41E4473 CRC64;
MGEYPKDMEI TDSFHTSMVQ SVLGSKFASD TLLHRYKTFN GFVASLTKEE SERMKGMDGV
VSVIPERVYS VQTSRSWDFL NFPENVPRTN VESNTIVGVI DSGIWANSGS FTDGGFGPPP
QKWKGKCDNF TCNYKVIGAR YFRIGGQFEP EDIINPTDTS GHGSHCASTA AGNRVPNANL
FGLGSGIARG GVPSARIAVY KVCWTSGCMN TDILAGYDAA IADGVDIISI SVGPTKVQHL
EYFDDESAIG AYHAMKSGIL TSKTADNLGP NRYTMVNLAP WFLSVAASTI DRKFFTDLKL
GNGQIIQGVS VNTFIPTQSN GYPLIFGGDV PAPGFNSSES SMCIDNSLNG ALVRGKIVLC
DGYYPSERVG FASGAAGVIF SSTLPLVAAY VFALPAMHIS ANDGQSVYNY LKSTSNPAAI
ISKSYEGIDS AAPYIAPFSS RGPNRITPNI LKPDIAAPGV DILAAWSPIS PISSVKGDRR
TSYTNIISGT SMACPHVTAT AVYVKSFHPS WSPAVLKSAL MTTATPLNPA LNSDAEFAYG
AGQINPLKAV NPGLVYDLGP NDYINFLCGQ GYSTVLLRRI TGDKNTCTSA NRGSVFNLNL
PSFALATARS SYNDVTYGRT VTNVGSARST YRAIISGYPS SLNIQVVPNV LTFTSVGQSL
SFTVRIQGTI NANLDSFSLT WDDGTHQVRS PIVVYVP
//
