ID V7BCI4_PHAVU Unreviewed; 1081 AA.
AC V7BCI4;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=PHAVU_007G084400g {ECO:0000313|EMBL:ESW15582.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW15582.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SIMILARITY: Belongs to the protein kinase superfamily. Ser/Thr protein
CC kinase family. {ECO:0000256|ARBA:ARBA00008684}.
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DR EMBL; CM002294; ESW15582.1; -; Genomic_DNA.
DR RefSeq; XP_007143588.1; XM_007143526.1.
DR AlphaFoldDB; V7BCI4; -.
DR EnsemblPlants; ESW15582; ESW15582; PHAVU_007G084400g.
DR GeneID; 18625273; -.
DR Gramene; ESW15582; ESW15582; PHAVU_007G084400g.
DR KEGG; pvu:PHAVU_007G084400g; -.
DR eggNOG; ENOG502QUMP; Eukaryota.
DR OMA; QTPCSWQ; -.
DR OrthoDB; 457890at2759; -.
DR Proteomes; UP000000226; Chromosome 7.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR GO; GO:0004672; F:protein kinase activity; IEA:InterPro.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 6.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR003591; Leu-rich_rpt_typical-subtyp.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR013210; LRR_N_plant-typ.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR017441; Protein_kinase_ATP_BS.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR27008; OS04G0122200 PROTEIN; 1.
DR PANTHER; PTHR27008:SF486; PROTEIN KINASE DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF00560; LRR_1; 10.
DR Pfam; PF13855; LRR_8; 2.
DR Pfam; PF08263; LRRNT_2; 1.
DR Pfam; PF00069; Pkinase; 1.
DR PRINTS; PR00019; LEURICHRPT.
DR SMART; SM00369; LRR_TYP; 8.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR SUPFAM; SSF52047; RNI-like; 1.
DR PROSITE; PS51450; LRR; 1.
DR PROSITE; PS00107; PROTEIN_KINASE_ATP; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741, ECO:0000256|PROSITE-
KW ProRule:PRU10141}; Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Signal {ECO:0000256|ARBA:ARBA00022729};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 716..737
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 784..1074
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1062..1081
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1064..1081
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 813
FT /ligand="ATP"
FT /ligand_id="ChEBI:CHEBI:30616"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10141"
SQ SEQUENCE 1081 AA; 117534 MW; 24A7F8A58BDD72DA CRC64;
MENIVSRSVT TLLFSMIFFC LTLTKIRVTC LSPDGQALLS LLPAAGPAAK SSPVLSSWKP
SSSTPCSWKG ITCSPQGRVI SLSIPDTFLN LSSLPPQLSS LSMLQLLNLS STNVSGSIPP
SFGQLSHLQL LDLSSNSLTG PIPAELGSLS LLQFLFLNSN RLTGSIPQHL SNLTLLEVLC
LQDNLLNGSI PSQLGSLTSL QQFRIGGNPY LTGQIPSHLG LLTNLTTFGA AATGLSGAIP
STFGNLINLQ TLALYDTEIS GSMPPELGLC SELRNLYLHM NKLTGSIPPQ LSKLQKLTSL
LLWGNALTGP IPAELSNCSS LVIFDVSSND LSGEIPGDFG KLVVLEQLHL SDNSLTGKIP
WQLSNCTSLS TVQLDKNQLS GTIPWELGKL TVLQSFFLWG NLVSGTIPSS FGNCSELYAL
DLSRNNLTGS LPEEIFGLKK LSKLLLLGNS LTGRLPPSVA NCQSLVRLRV GENQLSGQIP
KEIGQLQNLV FLDLYMNHFS GSIPVEVANI TVLELLDVHN NYLTGEIPSV IGELENLEQL
DLSRNSLTGK IPWSFGNFSY LNKLILNNNL LTGSIPKSIR NLQKLTLLDL SYNSLSGGIP
PEIGHVTSLT ISLDLSSNSF TGEIPESVSA LTQLQSLDLS HNMLYGEIKV LGSLTSLTSL
NISYNNFSGP IPVTPFFRTL SFNSYIQNPE LCQSIDGATC SSSLIRKNGL QSAKTIAMIT
VILASVTIIL IASWILVTRN HVYKVEKTLG ASTSASGAED FSYPWTFIPF QKVNFSIDNI
LDCLKDENVI GKGCSGVVYK AEMPNGELIA VKKLWKASKA DEILDSFAAE IQILGYIRHR
NIVRLIGYCS NRSVNLLLYK YIPNGNLRQL LQGNRNLDWE TRYKIAVGSA QGLAYLHHDC
VPTILHRDVK CNNILLDSKF EAYLADFGLA KLMHSPNYHH AMSRVAGSYG YIAPEYGYSM
NITEKSDVYS YGVVLLEILS GRSAVESHVG DGQHIVEWVK RKMGSFEPAV SILDTKLQGL
PDQMVQEMLQ TLGIAMFCVN SSPSERPTMK EVVALLMEVK SQPEEMGKTS QPLIKQSLNQ
S
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