ID V7BHM8_PHAVU Unreviewed; 501 AA.
AC V7BHM8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Aconitase/3-isopropylmalate dehydratase large subunit alpha/beta/alpha domain-containing protein {ECO:0000259|Pfam:PF00330};
GN ORFNames=PHAVU_007G232000g {ECO:0000313|EMBL:ESW17347.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW17347.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
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DR EMBL; CM002294; ESW17347.1; -; Genomic_DNA.
DR RefSeq; XP_007145353.1; XM_007145291.1.
DR AlphaFoldDB; V7BHM8; -.
DR STRING; 3885.V7BHM8; -.
DR EnsemblPlants; ESW17347; ESW17347; PHAVU_007G232000g.
DR GeneID; 18626791; -.
DR Gramene; ESW17347; ESW17347; PHAVU_007G232000g.
DR KEGG; pvu:PHAVU_007G232000g; -.
DR eggNOG; KOG0454; Eukaryota.
DR OMA; WDDHVVR; -.
DR OrthoDB; 1122834at2759; -.
DR UniPathway; UPA00048; UER00071.
DR Proteomes; UP000000226; Chromosome 7.
DR GO; GO:0003861; F:3-isopropylmalate dehydratase activity; IEA:UniProtKB-EC.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0009098; P:leucine biosynthetic process; IEA:UniProtKB-UniPathway.
DR CDD; cd01583; IPMI; 1.
DR Gene3D; 3.30.499.10; Aconitase, domain 3; 2.
DR InterPro; IPR015931; Acnase/IPM_dHydase_lsu_aba_1/3.
DR InterPro; IPR001030; Acoase/IPM_deHydtase_lsu_aba.
DR InterPro; IPR036008; Aconitase_4Fe-4S_dom.
DR InterPro; IPR006251; Homoacnase/IPMdehydase_lsu.
DR InterPro; IPR033941; IPMI_cat.
DR NCBIfam; TIGR01343; hacA_fam; 1.
DR PANTHER; PTHR43822:SF2; 3-ISOPROPYLMALATE DEHYDRATASE LARGE SUBUNIT, CHLOROPLASTIC; 1.
DR PANTHER; PTHR43822; HOMOACONITASE, MITOCHONDRIAL-RELATED; 1.
DR Pfam; PF00330; Aconitase; 1.
DR PRINTS; PR00415; ACONITASE.
DR SUPFAM; SSF53732; Aconitase iron-sulfur domain; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Lyase {ECO:0000256|ARBA:ARBA00023239};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226}.
FT DOMAIN 81..491
FT /note="Aconitase/3-isopropylmalate dehydratase large
FT subunit alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF00330"
SQ SEQUENCE 501 AA; 54731 MW; 19E7C571E54F5C2C CRC64;
MASSLLSPSF SSFLRTKKDL PLYAFSSQRC FKAVPKRIRC SVAAPQRQPS TTGSVRTAMT
MTEKILARAS EKAQLSPGDN VWVNIDVLMT HDVCGPGSIG IFKREFGEDA KVWDREKVVI
IPDHYIFTSD ERANRNVDIL RDFCQEQNIK YFYDIKDLGN FKANPDYKGV CHVALAQEGH
CRPGEVLLGT DSHTCTAGAF GQFATGIGNT DAGFVLGTGK LLLKVPPTLR FVMDGEMPDY
LLSKDLILQI IGEISVAGAT YKAMEFVGTT VESLSMEERM TLCNMVVEAG GKNGVVPADS
TTFKYIEGKT SLPYEPVYSD QKARFLSEYR FDVSKLEPVV AKPHSPDNRA LARECKDVKI
NRVYIGSCTG GKTEDFMAAA KVFLASGKKV KVPTFLVPAT QKVWMDVYTI PVPGSGGKTC
SQIFEEAGCD TPASPSCGAC LGGPKDTYAR MNEPQVCVST TNRNFPGRMG HKEGQIYLAS
PYTAAASALT GYVTDPREFL Q
//
