ID V7BPS2_PHAVU Unreviewed; 1015 AA.
AC V7BPS2;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 41.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=PHAVU_006G170500g {ECO:0000313|EMBL:ESW19974.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW19974.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
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DR EMBL; CM002293; ESW19974.1; -; Genomic_DNA.
DR RefSeq; XP_007147980.1; XM_007147918.1.
DR AlphaFoldDB; V7BPS2; -.
DR STRING; 3885.V7BPS2; -.
DR EnsemblPlants; ESW19974; ESW19974; PHAVU_006G170500g.
DR GeneID; 18629070; -.
DR Gramene; ESW19974; ESW19974; PHAVU_006G170500g.
DR eggNOG; ENOG502QW9B; Eukaryota.
DR OMA; HVVKIAF; -.
DR OrthoDB; 991910at2759; -.
DR Proteomes; UP000000226; Chromosome 6.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd14066; STKc_IRAK; 1.
DR Gene3D; 2.60.120.430; Galactose-binding lectin; 1.
DR Gene3D; 3.80.10.10; Ribonuclease Inhibitor; 2.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR001611; Leu-rich_rpt.
DR InterPro; IPR032675; LRR_dom_sf.
DR InterPro; IPR021720; Malectin_dom.
DR InterPro; IPR000719; Prot_kinase_dom.
DR InterPro; IPR001245; Ser-Thr/Tyr_kinase_cat_dom.
DR InterPro; IPR008271; Ser/Thr_kinase_AS.
DR PANTHER; PTHR48006; LEUCINE-RICH REPEAT-CONTAINING PROTEIN DDB_G0281931-RELATED; 1.
DR PANTHER; PTHR48006:SF72; LRR RECEPTOR-LIKE SERINE_THREONINE-PROTEIN KINASE RFK1-RELATED; 1.
DR Pfam; PF00560; LRR_1; 2.
DR Pfam; PF11721; Malectin; 1.
DR Pfam; PF07714; PK_Tyr_Ser-Thr; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF52058; L domain-like; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
DR PROSITE; PS00108; PROTEIN_KINASE_ST; 1.
PE 4: Predicted;
KW Leucine-rich repeat {ECO:0000256|ARBA:ARBA00022614};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..1015
FT /note="non-specific serine/threonine protein kinase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004755195"
FT TRANSMEM 612..633
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 671..948
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 975..1015
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 976..1015
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1015 AA; 113032 MW; 49C70F5906A834F1 CRC64;
MRAVNFFIFL FIALSCFQLL RVSASKVPQE EVVALREIAS AMGSKYWKFD ADSCSIEMVG
LTQEPPAESE RSIGCDCSFE DNAVCHVVKM TLKRLSLPGT LPPQLAKLPF LREVDFAYNC
FTGSIPEEWA SMKLTSISLL VNRLSGEIPK HLGNFTSLTY LMLEGNQFSG AVPPELGKLI
NLQTLVLSSN QLTGNLPLTF AGLQNLTDFR INDNNFTGTI PSFIPSWQLL QRLEMYASGL
EGPFPSNISL LKNLVMLRIS DIESPAQVFP HLENMEKLSI LVLRSCNLSG VIPSYVWTMR
NLAVLDVSFN KLVGEISSIV SARRLRFIYL TGNMLSGNIP NSILKDGSSI DLSYNNFTWQ
DETSCKDGIR NLNLNLFRSS IRKNKLEEYV PCSKNFSCSR FSSCLHVNCG GKDVSVKDDK
GENLYVGDED VQGGAATYFY SNDDHWGFSS TGDFMDDFES QNVRYIVSLP SSNMPELYKT
ARVSPITLTY FHNCMANGNY TVNLHFAEIK FTNDKTYKSL GKRIFDIYVQ GRRARKNFNI
ENETNVTEKP LVLPIHNIGI TNNILEIRFY WAGKGTTRIP DVGVYGPLVS AISVVSDSRI
CSNGEKKVDR SIIIAIVAGA LCSVLFLSGL IWWKWKGFFR GKLQKKEGAK DGDIQAGNFS
LEHIRAATND FSSANKIGEG GFGPVYKGEL LDGTFIAVKQ LSSQSRQGNR EFINEIGLIS
CVQHPNLVKL HGYCAEGEQL LLVYEYMENN SLARALFGSE NRQLKLDWPT RFRICIGIAK
GLAFLHDESR FKIVHRDIKA SNVLLDGDLN PKISDFGLAR LDEAEKTHIS TRVAGTIGYM
APEYALWGHL TYKADVYSFG VLALEIVSGK NNNNYLPDDG STCLLDWACQ LNQAKKLVGL
VDERLGPDLN KTEVEKVVRI ALLCTNVSLS LRPTMSEVVN MLEGHLDIPD AIPEPSTYSE
DLRFKALRDL NEHRSKQSLS VNQSQNSSTH TFSSASASNT HTSSNIEDYC SVDNS
//
