ID V7BWV9_PHAVU Unreviewed; 330 AA.
AC V7BWV9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=fructokinase {ECO:0000256|ARBA:ARBA00038887};
DE EC=2.7.1.4 {ECO:0000256|ARBA:ARBA00038887};
GN ORFNames=PHAVU_005G153300g {ECO:0000313|EMBL:ESW22429.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW22429.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- FUNCTION: May play an important role in maintaining the flux of carbon
CC towards starch formation. {ECO:0000256|ARBA:ARBA00037195}.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + D-fructose = ADP + D-fructose 6-phosphate + H(+);
CC Xref=Rhea:RHEA:16125, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:37721, ChEBI:CHEBI:61527, ChEBI:CHEBI:456216; EC=2.7.1.4;
CC Evidence={ECO:0000256|ARBA:ARBA00036647};
CC -!- PATHWAY: Glycan biosynthesis; starch biosynthesis.
CC {ECO:0000256|ARBA:ARBA00004727}.
CC -!- SIMILARITY: Belongs to the carbohydrate kinase PfkB family.
CC {ECO:0000256|ARBA:ARBA00010688, ECO:0000256|RuleBase:RU003704}.
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DR EMBL; CM002292; ESW22429.1; -; Genomic_DNA.
DR RefSeq; XP_007150435.1; XM_007150373.1.
DR AlphaFoldDB; V7BWV9; -.
DR STRING; 3885.V7BWV9; -.
DR EnsemblPlants; ESW22429; ESW22429; PHAVU_005G153300g.
DR GeneID; 18631176; -.
DR Gramene; ESW22429; ESW22429; PHAVU_005G153300g.
DR KEGG; pvu:PHAVU_005G153300g; -.
DR eggNOG; KOG2855; Eukaryota.
DR OMA; AQYQFRG; -.
DR OrthoDB; 5486729at2759; -.
DR Proteomes; UP000000226; Chromosome 5.
DR GO; GO:0008865; F:fructokinase activity; IEA:UniProt.
DR GO; GO:0006000; P:fructose metabolic process; IEA:UniProt.
DR CDD; cd01167; bac_FRK; 1.
DR Gene3D; 3.40.1190.20; -; 1.
DR InterPro; IPR002173; Carboh/pur_kinase_PfkB_CS.
DR InterPro; IPR011611; PfkB_dom.
DR InterPro; IPR002139; Ribo/fructo_kinase.
DR InterPro; IPR029056; Ribokinase-like.
DR PANTHER; PTHR43085:SF24; FRUCTOKINASE-4-RELATED; 1.
DR PANTHER; PTHR43085; HEXOKINASE FAMILY MEMBER; 1.
DR Pfam; PF00294; PfkB; 1.
DR PRINTS; PR00990; RIBOKINASE.
DR SUPFAM; SSF53613; Ribokinase-like; 1.
DR PROSITE; PS00583; PFKB_KINASES_1; 1.
DR PROSITE; PS00584; PFKB_KINASES_2; 1.
PE 3: Inferred from homology;
KW Kinase {ECO:0000256|RuleBase:RU003704};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Transferase {ECO:0000256|ARBA:ARBA00022679, ECO:0000256|RuleBase:RU003704}.
FT DOMAIN 14..319
FT /note="Carbohydrate kinase PfkB"
FT /evidence="ECO:0000259|Pfam:PF00294"
SQ SEQUENCE 330 AA; 35293 MW; 5649CE1ED343E0F0 CRC64;
MAFNNGVPAT GSGLIASFGE MLIDFVPTVS GVSLAEAPGF LKAPGGAPAN VAIAVARLGG
KAAFVGKLGD DEFGHMLAGI LKENGVRADG ITFDQGARTA LAFVTLRADG EREFMFYRNP
SADMLLKPEE LNLELIRSAK VFHYGSISLI VEPCRSAHLK AMEVAREAGC LLSYDPNLRL
PLWPSADEAR KQILSIWEKA DLIKVSDVEL EFLTGSDKID DASALSLWHP NLKLLLVTLG
EQGSRYYTKS FKGSVDAFHV NTVDTTGAGD SFVGALLSKI VDDQSILEDE PRLRDVLKFA
NACGAITTTQ KGAIPALPKE EDALKIIEGA
//
