ID V7CDG6_PHAVU Unreviewed; 809 AA.
AC V7CDG6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=TIR domain-containing protein {ECO:0000259|PROSITE:PS50104};
GN ORFNames=PHAVU_003G269200g {ECO:0000313|EMBL:ESW28222.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW28222.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
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DR EMBL; CM002290; ESW28222.1; -; Genomic_DNA.
DR RefSeq; XP_007156228.1; XM_007156166.1.
DR AlphaFoldDB; V7CDG6; -.
DR STRING; 3885.V7CDG6; -.
DR EnsemblPlants; ESW28222; ESW28222; PHAVU_003G269200g.
DR GeneID; 18636184; -.
DR Gramene; ESW28222; ESW28222; PHAVU_003G269200g.
DR KEGG; pvu:PHAVU_003G269200g; -.
DR OMA; YPSESNG; -.
DR OrthoDB; 911496at2759; -.
DR Proteomes; UP000000226; Chromosome 3.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR GO; GO:0008757; F:S-adenosylmethionine-dependent methyltransferase activity; IEA:UniProt.
DR GO; GO:0006952; P:defense response; IEA:InterPro.
DR GO; GO:0007165; P:signal transduction; IEA:InterPro.
DR Gene3D; 1.10.8.430; Helical domain of apoptotic protease-activating factors; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR InterPro; IPR042197; Apaf_helical.
DR InterPro; IPR044974; Disease_R_plants.
DR InterPro; IPR002182; NB-ARC.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR000157; TIR_dom.
DR InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR InterPro; IPR036390; WH_DNA-bd_sf.
DR PANTHER; PTHR11017:SF588; ADP-RIBOSYL CYCLASE_CYCLIC ADP-RIBOSE HYDROLASE; 1.
DR PANTHER; PTHR11017; LEUCINE-RICH REPEAT-CONTAINING PROTEIN; 1.
DR Pfam; PF00931; NB-ARC; 1.
DR Pfam; PF01582; TIR; 1.
DR PRINTS; PR00364; DISEASERSIST.
DR SMART; SM00255; TIR; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR PROSITE; PS50104; TIR; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 726..744
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 751..769
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 775..798
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 12..179
FT /note="TIR"
FT /evidence="ECO:0000259|PROSITE:PS50104"
SQ SEQUENCE 809 AA; 93309 MW; FFF79BF95697A0A0 CRC64;
MASSTSCDVS EIKHDVFISF RGTDVRRGLL SHLKRELDRK NIDAYVDERL DKGGEISSKL
LRAIEGSQVL LVVFSKDYAS SQWCLKELAK MVECMETSKQ IVLPVFFNVD PSDVRHQNGD
YGDALAKHEE KFKGNMLKVQ SWRSALKKAG SLSGFHYPTN YRNESDLVYE IVEYISAKLS
KLYPSESNGL VGFDQNITQI QSSLRMESNE VVFVGIWGMG GIGKTTIARA IFDKCSLQYD
GCCFFNVREE LQQHGSSNLR ERFIYELFEG EGLRTSKARF FNSALRRMGR KKVMVVLDDV
NTSEELKDLV TKPICFGAGS RVIVTSRDQD VLTSGGIHQI HEVKEMDPRD SLKLFCLNAF
NESQPKTGYE KLTEEVLEIA QGNPLALKVL GAHFHSRSSI NTWKCSLSKF KKYPNEKIQS
VLRFSYDGLH VVEKKAFLDI AFFFEEDSKD YVIKQLDAWG LYGASGVEVL QRKALITVSS
DNRIQMHDLI RQMGCEIVRQ ECIIYPGRRT RLRDKEEVYN VLRYKLGSDK VEAMQVDLLS
RIKDLPLKLG TFKKMPRLRF LKFYLPYADI FLPPNQDGNL WFGQHEFPLL LSACCEELMK
VACEIHIKCV DYLYIDGCSH PSRLNKSSVT SPLGSRGMEP MSLLLMLWKE PLSSLRNLEC
SDMLDQQWKT LSDELLCLRS TYYLKLSKKS TGQDSGKPKL HILFDGLRFY ERISVSQLEN
SNVGQYRVWF LFCAGFNFLL YLFLRRPWFQ FLFSFPFQFF CTFFLYLFSH FTSLFYPPLA
FSLSWVRAFF LLLFFYILGK LCSWFLRVG
//
