ID V7CHC6_PHAVU Unreviewed; 542 AA.
AC V7CHC6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 43.
DE RecName: Full=Glucose-methanol-choline oxidoreductase N-terminal domain-containing protein {ECO:0000259|PROSITE:PS00624};
GN ORFNames=PHAVU_002G084200g {ECO:0000313|EMBL:ESW29607.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW29607.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- COFACTOR:
CC Name=FAD; Xref=ChEBI:CHEBI:57692;
CC Evidence={ECO:0000256|ARBA:ARBA00001974,
CC ECO:0000256|PIRSR:PIRSR000137-2};
CC -!- SIMILARITY: Belongs to the GMC oxidoreductase family.
CC {ECO:0000256|ARBA:ARBA00010790}.
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DR EMBL; CM002289; ESW29607.1; -; Genomic_DNA.
DR RefSeq; XP_007157613.1; XM_007157551.1.
DR AlphaFoldDB; V7CHC6; -.
DR STRING; 3885.V7CHC6; -.
DR EnsemblPlants; ESW29607; ESW29607; PHAVU_002G084200g.
DR GeneID; 18637342; -.
DR Gramene; ESW29607; ESW29607; PHAVU_002G084200g.
DR KEGG; pvu:PHAVU_002G084200g; -.
DR eggNOG; KOG1238; Eukaryota.
DR OMA; TDPDPNM; -.
DR OrthoDB; 52047at2759; -.
DR Proteomes; UP000000226; Chromosome 2.
DR GO; GO:0050660; F:flavin adenine dinucleotide binding; IEA:InterPro.
DR GO; GO:0016614; F:oxidoreductase activity, acting on CH-OH group of donors; IEA:InterPro.
DR Gene3D; 3.30.410.40; -; 1.
DR Gene3D; 3.50.50.60; FAD/NAD(P)-binding domain; 1.
DR InterPro; IPR036188; FAD/NAD-bd_sf.
DR InterPro; IPR012132; GMC_OxRdtase.
DR InterPro; IPR000172; GMC_OxRdtase_N.
DR InterPro; IPR007867; GMC_OxRtase_C.
DR PANTHER; PTHR45968:SF19; GLUCOSE-METHANOL-CHOLINE (GMC) OXIDOREDUCTASE FAMILY PROTEIN; 1.
DR PANTHER; PTHR45968; OSJNBA0019K04.7 PROTEIN; 1.
DR Pfam; PF05199; GMC_oxred_C; 1.
DR Pfam; PF00732; GMC_oxred_N; 1.
DR PIRSF; PIRSF000137; Alcohol_oxidase; 2.
DR SUPFAM; SSF54373; FAD-linked reductases, C-terminal domain; 1.
DR SUPFAM; SSF51905; FAD/NAD(P)-binding domain; 1.
DR PROSITE; PS00624; GMC_OXRED_2; 1.
PE 3: Inferred from homology;
KW Disulfide bond {ECO:0000256|PIRSR:PIRSR000137-3};
KW FAD {ECO:0000256|PIRSR:PIRSR000137-2};
KW Flavoprotein {ECO:0000256|PIRSR:PIRSR000137-2};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..27
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 28..542
FT /note="Glucose-methanol-choline oxidoreductase N-terminal
FT domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004757775"
FT DOMAIN 295..309
FT /note="Glucose-methanol-choline oxidoreductase N-terminal"
FT /evidence="ECO:0000259|PROSITE:PS00624"
FT BINDING 128
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 242
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT BINDING 499
FT /ligand="FAD"
FT /ligand_id="ChEBI:CHEBI:57692"
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-2"
FT DISULFID 423..462
FT /evidence="ECO:0000256|PIRSR:PIRSR000137-3"
SQ SEQUENCE 542 AA; 59799 MW; 329AE8DF0EA315E7 CRC64;
MELPQINLVH KLLIAFVLFF LASLVLSVPL EPPGNIRQWH MTSDVKEVAG KSYDYIIVGG
GTCGCALAAT LSEKFSVLLV ERGGSPYGNP LVIDRRYYGI PLLETDKYIS VAQSFTSQDG
VDNVRGRVLG GSSAINGGFY SRASEEYVCK AGWDKKLVKE AYEWVESKVV FPPFYLSPWQ
SVAEFSILEA GVLPYNGFSL EHIKGTKISG SVFDEFGKRH TSADLLNAGN PENLTVLINS
TVKSIIFRHN SYRNETRAKG ISFMQSNGTL DETHEAYIKK VQNSSSRGDV ILAAGALGSP
QLLLLSGIGP KEQLRRFNIT LVRDMQGVGK EMQDNPCIAV LVDSKPQNRL PDPPQIAGIT
DDYKIIVEAS ILPLSSNSSR VNVAAKIAMP TSKGVLHLNN TDPRLNPSVR FNYLTSENDM
QECVKMTKLL ERIARSKSIA FFLGESRQEK LTSADVDLRN FCKKNVRTIY HYHGGCTVGS
VVDEHYKVYG IKGLRVLDGS TFSDSPGTNP MATLLMLGRY QGLRMLSERN AVSDYNVKDK
TK
//
