ID V7CI88_PHAVU Unreviewed; 3877 AA.
AC V7CI88;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 56.
DE SubName: Full=Uncharacterized protein {ECO:0000313|EMBL:ESW29912.1};
GN ORFNames=PHAVU_002G108900g {ECO:0000313|EMBL:ESW29912.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW29912.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; CM002289; ESW29912.1; -; Genomic_DNA.
DR RefSeq; XP_007157918.1; XM_007157856.1.
DR EnsemblPlants; ESW29912; ESW29912; PHAVU_002G108900g.
DR GeneID; 18637596; -.
DR Gramene; ESW29912; ESW29912; PHAVU_002G108900g.
DR KEGG; pvu:PHAVU_002G108900g; -.
DR OMA; CLDLYGQ; -.
DR OrthoDB; 3666795at2759; -.
DR Proteomes; UP000000226; Chromosome 2.
DR GO; GO:0004674; F:protein serine/threonine kinase activity; IEA:UniProtKB-EC.
DR CDD; cd05163; PIKK_TRRAP; 1.
DR Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 2.
DR Gene3D; 1.10.1070.11; Phosphatidylinositol 3-/4-kinase, catalytic domain; 1.
DR InterPro; IPR011989; ARM-like.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR003152; FATC_dom.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000403; PI3/4_kinase_cat_dom.
DR InterPro; IPR036940; PI3/4_kinase_cat_sf.
DR InterPro; IPR003151; PIK-rel_kinase_FAT.
DR InterPro; IPR014009; PIK_FAT.
DR InterPro; IPR046807; Tra1_central.
DR InterPro; IPR046805; Tra1_ring.
DR PANTHER; PTHR11139; ATAXIA TELANGIECTASIA MUTATED ATM -RELATED; 1.
DR PANTHER; PTHR11139:SF1; TRANSFORMATION_TRANSCRIPTION DOMAIN-ASSOCIATED PROTEIN; 1.
DR Pfam; PF02259; FAT; 1.
DR Pfam; PF02260; FATC; 1.
DR Pfam; PF00454; PI3_PI4_kinase; 1.
DR Pfam; PF20175; Tra1_central; 1.
DR Pfam; PF20206; Tra1_ring; 1.
DR SMART; SM01343; FATC; 1.
DR SMART; SM00146; PI3Kc; 1.
DR SUPFAM; SSF48371; ARM repeat; 3.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS51189; FAT; 1.
DR PROSITE; PS51190; FATC; 1.
DR PROSITE; PS50290; PI3_4_KINASE_3; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000000226}.
FT DOMAIN 2655..3196
FT /note="FAT"
FT /evidence="ECO:0000259|PROSITE:PS51189"
FT DOMAIN 3506..3828
FT /note="PI3K/PI4K catalytic"
FT /evidence="ECO:0000259|PROSITE:PS50290"
FT DOMAIN 3841..3877
FT /note="FATC"
FT /evidence="ECO:0000259|PROSITE:PS51190"
FT REGION 1582..1614
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2010..2029
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2281..2303
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 3212..3305
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3212..3230
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3245..3267
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 3274..3305
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 3877 AA; 437406 MW; A2C66AE3F60DA6AC CRC64;
MSPVQNFEQH SRHLVESDLP IQARLQMVME VRDSLEIAHT AEYLNFLKCY FRAFSAILLQ
ITKPQFVDNP EHKLRNIVVE ILNRLPHSEV LRPFVQDLLK VAMQVLTTDN EENGLICIRI
IFDLLRNFRP TLENEVQPFL DFVCKIYQNF KLTVSHFFDN MAMTGEDVKP METSLSDQGI
NTTTATGSQL NPSTRSFKIV TESPLVVMFL FQLYSRLVQA NIPQLLPLMV AAISVPGPER
VPPHLKTHFI ELKGAQVKTV SFLTYLLKSY ADYIRPHEES ICKSIVNLLV TCSDSVSIRK
ELLISLKHVL GTDFRRGLFP LIDTLLEERV LVGTGRACFE TLRPLAYSLL AEIVHHVRQD
LSLSQLSRII YLFSSNMHDA SLSLSIHTTC ARLMLNLVEP IFEKGVDQQS TDEARILLGR
ILDAFVGKFS TFKRTIPQLL EEGEEGKDRA TLRSKLELPV QAVLALQVPV EHSKEVNDCK
HLIKTLVMGM KTIIWSITHA HSPRPQTLVS PSSNLSPPQA LRGMREDEVC KASGVLKSGV
HCLALFKEKD EEREMLHLFS QILAIMEPRD LMDMFSLCMP ELFECMISNT QLVHIFSTLL
AAPKVYRPFA DVLVNFLVSG KLDALKQPDS PAAKLALHLF RFIFGAVTKA PADFERILQP
HAPVIMEFCM KNATEVEKPL GYMQLLRTMF KALSGCKYEL LLRDLVPMLQ PCLNMLLAML
EGPTAEDMRD LLLELCLTLP ARLSSLLPYL SRLMKPLVLC LKGSDELVSL GLRTLEFWVD
SLNPDFLEPI MASVMSEVIL ALWSHLRPAP YPWGAKALQL LGKLGGRNRR FLKEPLALEC
KENPEHGLRL ILTFEPATPF LVPLDRCINL AVEAVMNKNC GMDAFYRKQA LKFLRVCLSS
QLNLPGSVAD DGSTSKQLSA LLVSTVDQTS RRSELMDVKA DLGVKTKTQL MAEKSVFKIL
LMTVIAANGE TDLTDPTDDF VVNICRHFAV VFHIDSSSSN VSVAALGGSS LSNNVHVGSR
LKSNACSNLK ELDPLIFLDA LVEILADENR LHAKAALGAL NVFAETLVFL ARSKHTDFIM
SRGPGTPMIV SSPSMNPVYS PPPSVRVPVF EQLLPRLLHC CYGLTWQAQM GGVMGLGALV
GKVTVETLCL FQVRIVRGLI YVLKKLPIYA SKEQEETSQV LTQVLRVVNN VDEANSEARK
QSFQGVVDFL AQELFNQNAS ITVRKNVQSC LALLASRTGS EVSELLEQLY QPFLQPLIVR
SLKLKTVDQQ VGTVTALNFC LALRPPLLKL TPELVNFLQE ALQIAESDDN AWVAKFINPK
VMTSLTKLRT ACIELLCTTM AWADFKTPNH SELRAKIISM FFKSLTCRTP EIVAVAKEGL
RQVINQRMPK ELLQSSLRPI LVNLAHTKNL SMPLLLGLAR LLELLSNWFN VTLGGKLLEH
LKRWLEPEKL AQSQKSWKSG EEPKIAAAII ELFHLLPPAA SKFLDELVTL TIDLEGALPP
GLVYSEINSP YRLPLTKFLN RYASLAVDYF LARLSEPKYF RRFMYIIRSE AGQPLRDELA
KSPQKILASA FSEFIPKSDV TMTPASTSTH TSLLGEESVA PSTDASNPPA PSTSATSDAY
FQGLALIKTL VKLIPGWLQS NRSVFDTLVL VWKSPARISR LQKEQELNLV QVKESKWLVK
CFLNYLRHDK NEVNVLFDIL TIFLFHSRID YTFLKEFYII EVAEGYPPGM KKALLLHFLS
LFQSKQLGHD HLVTVMQMLI LPMLAHAFQN GQSWEVVDPG IIKTIVDKLL DPPEEVSAEY
DEPLRIELLQ LATLLLKYLQ NDLVHHRKEL IKFGWNHLKR EDTASKQWAF VNVCHFLEAY
QAPEKIILQV FVALLRTCQP ENKMLVKQAL DILMPALPRR LPLGDSRMPI WIRYTKKILV
EEGHSIPNLI HIFQLIVRHS DLFYSCRAQF VPQMVNSLSR LGLPYNTTAE NRRLAIELAG
LVVNWERQRQ NEMKVVTDSD APNQINDVFN PSSADSKRSV DGSTFPEDTT KRVKAEPGLQ
SMCVMSPGGP SSITNIETPG SASQPDEEFK PNAAMEEMII NFLIRVALVI EPKDKEASAM
YKQALELLSQ ALEVWPNANV KFNYLEKLLS SIQPSQAKDP STALAQGLDV MNKVLEKQPH
LFIRNNINQI SQILEPCFKH KLLDAGKSFC SLLRMIFVAF PQEATTTPAD VKLLYQKLDD
LIQKHATTVT APQTASDDNN ASSISFLLLV IKTLTEVQRN FVDPLILVRI LQRLQRDMGS
AAGPHLRQGQ RPDPDSAVTS SRQDADVGAV ISNVKSILKL ITDRVMVVSE CKRSVSQILN
ALLSEKGIDA SVLLCILDVV KGWIEDDFCK QGTPVTPSSF LTPKEIVSFL QKLSQVDKQN
FTPVALEEWD RKYLELLYGI CADSNKYPLP LRQEVFQKVE RLYMLGLRAK DLEVRMKFFS
LYHESLGKTL FTRLQFIIQI QDWGALSDVF WLKQGLDLLL AILVEDKPIT LAPNSARVQP
LLVSSSIIEL SGMQHKVNDV SEGSEDAPLT LETLVHKHAQ FLNSMSKLQV VDLLIPLREL
AHTDANVAYH LWVLVFPIVW VTLHKEEQVT LAKPMINLLS KDYHKRQQAN RPNVVQALLE
GLQLSHPQPR MPSELIKYIG KTYNAWHIAL ALLESHVMLF PNDSKCSESL AELYRLLNEE
DMRCGLWKKR SVTAETRAGL SLVQHGYWHR AQSLFYQAMV KATQGTYNNT VPKAEMCLWE
EQWLYCASQL SQWEALADFG KSVENYEILL DSLWKLPDWT YMKEHVIPKA QVEETPKLRL
IQAYFALHDK NTNGVGDAEN MVGKAVDLSL EQWWQLPEMS VHSRIPLLQQ FQQIVEVQES
ARILIDISNG NKGNSVVGVQ GNLYADLKDI LETWRLRTPN EWDNMSVWYD LLQWRNEMYN
SVIDAFKDFG ATNSALHHLG YRDKAWTVNR LAHIARKQGL FDVCVTILEK LYGHSTMEVQ
EAFVKITEQA KAYLENKGEL TSGINLINST NLEYFPAKHK AEIFRLKGDF LLKLNDSEST
NVAYSNAISL FKNLPKGWIS WGDYCDMAYR ETHEEIWLEY AVSCFLQGIK FGVSNSRSHL
ARVLYLLSFD TSNEPVGRAF DKYYEQIPHW VWLSWIPQLL LSLQRTEAPH CKLVLLKIAT
LYPQALYYWL RTYLLERRDV ANKSELGRIA MAQQRSQQSV SGTSTGSLGG LADGNARGVQ
GPGGSNLPTD IQAHQGSQPS GGIGSHDGGN SHGQEPERST SAESSMHNGN DQPLQQGSAN
LNEGGQNTLR RAAGALGFVA SAASAFDAAK DIMEALRGKH ANLASELEIL LTEIGSRFVT
LPEERLLAVV NALLHRCYKY PTATTAEVPQ SLKKELSGVC RACFSADAVN KHVDFVREYK
QDFERDLDPE STATFPSTLS QLTERLKHWK NVLQSNVEDR FPAVLKLEEE SKVLRDFHVI
DVEVPGQYFT DQEIAPDHTV KLDRVAADIP IVRRHGSSFR RLTLIGSDGS QRHFIVQTSL
TPNARSDERI LQLFRVMNQM FEKHKESRRR HICIHTPIII PVWSQVRMVE DDLMYSTFLE
VYENHCARND READLPITYF KEQLNQAISG QISPEAVVDL RLQAYNEITK NLVNDNIFSQ
YMYKTLPSGN HSWAFKKQFA VQLALSSFMS FMLQIGGRSP NKILFAKNTG KIFQTDFHPA
YDANGLIEFN EPVPFRLTRN MQAFFSHGVE GLIVSSMCAA AQAVASPKQS QHLWHHLAMF
FRDELLSWSW RRPLGMPMAP MAAGGTMSPV DFKQKVVTNV EHVITRVKGI APQNFSEEEE
NVMDPPQPVQ RGVTELVEAA LNPRNLCMMD PTWHPWF
//
