ID V7CKE1_PHAVU Unreviewed; 619 AA.
AC V7CKE1;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent) {ECO:0000256|ARBA:ARBA00012728};
DE EC=5.4.2.2 {ECO:0000256|ARBA:ARBA00012728};
GN ORFNames=PHAVU_002G096000g {ECO:0000313|EMBL:ESW29750.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW29750.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate;
CC Xref=Rhea:RHEA:23536, ChEBI:CHEBI:58225, ChEBI:CHEBI:58601;
CC EC=5.4.2.2; Evidence={ECO:0000256|ARBA:ARBA00000443};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000256|ARBA:ARBA00001946};
CC -!- SIMILARITY: Belongs to the phosphohexose mutase family.
CC {ECO:0000256|ARBA:ARBA00010231}.
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DR EMBL; CM002289; ESW29750.1; -; Genomic_DNA.
DR RefSeq; XP_007157756.1; XM_007157694.1.
DR AlphaFoldDB; V7CKE1; -.
DR STRING; 3885.V7CKE1; -.
DR EnsemblPlants; ESW29750; ESW29750; PHAVU_002G096000g.
DR GeneID; 18637461; -.
DR Gramene; ESW29750; ESW29750; PHAVU_002G096000g.
DR KEGG; pvu:PHAVU_002G096000g; -.
DR eggNOG; KOG1220; Eukaryota.
DR OMA; GQHGWVH; -.
DR OrthoDB; 1775085at2759; -.
DR Proteomes; UP000000226; Chromosome 2.
DR GO; GO:0016868; F:intramolecular phosphotransferase activity; IEA:InterPro.
DR GO; GO:0006006; P:glucose metabolic process; IEA:UniProtKB-KW.
DR CDD; cd03089; PMM_PGM; 1.
DR Gene3D; 3.40.120.10; Alpha-D-Glucose-1,6-Bisphosphate, subunit A, domain 3; 3.
DR InterPro; IPR005844; A-D-PHexomutase_a/b/a-I.
DR InterPro; IPR016055; A-D-PHexomutase_a/b/a-I/II/III.
DR InterPro; IPR005845; A-D-PHexomutase_a/b/a-II.
DR InterPro; IPR005846; A-D-PHexomutase_a/b/a-III.
DR InterPro; IPR005841; Alpha-D-phosphohexomutase_SF.
DR PANTHER; PTHR42946:SF2; PHOSPHOGLUCOMUTASE (ALPHA-D-GLUCOSE-1,6-BISPHOSPHATE-DEPENDENT); 1.
DR PANTHER; PTHR42946; PHOSPHOHEXOSE MUTASE; 1.
DR Pfam; PF02878; PGM_PMM_I; 1.
DR Pfam; PF02879; PGM_PMM_II; 1.
DR Pfam; PF02880; PGM_PMM_III; 1.
DR PRINTS; PR00509; PGMPMM.
DR SUPFAM; SSF53738; Phosphoglucomutase, first 3 domains; 3.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277};
KW Glucose metabolism {ECO:0000256|ARBA:ARBA00022526};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226}.
FT DOMAIN 72..216
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02878"
FT DOMAIN 266..351
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02879"
FT DOMAIN 355..455
FT /note="Alpha-D-phosphohexomutase alpha/beta/alpha"
FT /evidence="ECO:0000259|Pfam:PF02880"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1..20
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 619 AA; 67792 MW; 807211F9AB474D09 CRC64;
MAASTSPNFS TSLDKNTHKT KFPSSAGKKI LHNKVGFSFS VPFNKSVGVK SFGTAKYDEV
VVDDELEKIR RLQNGSDVRG VALEGEKGRK VDLTPPAVEA ISESFGEWVI NGLEAERGYP
LENVRVSLGR DPRITGSKLS VAVFAGLSRA GCMVFDMGLA TTPACFMSTI LSPFAYDASI
MMTASHLPYT RNGLKFFTKR GGLTSTEVEE ICDKAARKYA NRMTKVSTLL SVLPTKVDFM
STYAMHLREI ITERINHPLY YDTPLQGFQI IVNAGNGSGG FFTWDVLDKL GADTFGSLHL
TPDGMFPNHI PNPEDKTAMA LTRAAVLENS ADLGVVFDTD VDRSGVVDNK GNPINGDKLI
ALMSAIVLRE HPGSTIVTDA RTSMALTRFI TDRGGNHCLY RVGYRNVIDK GVQLDSGGVE
THLMMETSGH GALKENHFLD DGAYMVVKII IEMVRMKLAG SNEGIGSLIK DLEEPYESVE
LRINIVSEPR HAKAKGSEAI QTFRNYIEEG RLRGWELDSC GDCWVSEGCL VDTNDDPAPI
DAQMYRAKVS NDRHGQHGWV HMRQSIHNPN IAVNLQSSVP GGCLSMARAF RDEFLKASGV
HTFLDITQVD KFAEKGSMA
//
