ID V7CS69_PHAVU Unreviewed; 484 AA.
AC V7CS69;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 37.
DE RecName: Full=Legumain prodomain domain-containing protein {ECO:0000259|Pfam:PF20985};
GN ORFNames=PHAVU_001G033500g {ECO:0000313|EMBL:ESW32979.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW32979.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SIMILARITY: Belongs to the peptidase C13 family.
CC {ECO:0000256|ARBA:ARBA00009941}.
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DR EMBL; CM002288; ESW32979.1; -; Genomic_DNA.
DR RefSeq; XP_007160985.1; XM_007160923.1.
DR AlphaFoldDB; V7CS69; -.
DR STRING; 3885.V7CS69; -.
DR MEROPS; C13.002; -.
DR EnsemblPlants; ESW32979; ESW32979; PHAVU_001G033500g.
DR GeneID; 18640247; -.
DR Gramene; ESW32979; ESW32979; PHAVU_001G033500g.
DR KEGG; pvu:PHAVU_001G033500g; -.
DR OMA; DQGTRWA; -.
DR OrthoDB; 2951493at2759; -.
DR Proteomes; UP000000226; Chromosome 1.
DR GO; GO:0004197; F:cysteine-type endopeptidase activity; IEA:InterPro.
DR GO; GO:0051603; P:proteolysis involved in protein catabolic process; IEA:InterPro.
DR CDD; cd21115; legumain_C; 1.
DR Gene3D; 1.10.132.130; -; 1.
DR Gene3D; 3.40.50.1460; -; 1.
DR InterPro; IPR043577; AE.
DR InterPro; IPR048501; Legum_prodom.
DR InterPro; IPR046427; Legumain_prodom_sf.
DR InterPro; IPR001096; Peptidase_C13.
DR PANTHER; PTHR12000; HEMOGLOBINASE FAMILY MEMBER; 1.
DR PANTHER; PTHR12000:SF57; VACUOLAR-PROCESSING ENZYME; 1.
DR Pfam; PF20985; Legum_prodom; 1.
DR Pfam; PF01650; Peptidase_C13; 1.
DR PIRSF; PIRSF500139; AE; 1.
DR PIRSF; PIRSF019663; Legumain; 1.
DR PRINTS; PR00776; HEMOGLOBNASE.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Protease {ECO:0000256|ARBA:ARBA00022670};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..484
FT /note="Legumain prodomain domain-containing protein"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004755721"
FT DOMAIN 371..467
FT /note="Legumain prodomain"
FT /evidence="ECO:0000259|Pfam:PF20985"
FT ACT_SITE 167
FT /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
FT ACT_SITE 209
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR019663-1"
SQ SEQUENCE 484 AA; 53375 MW; B478ABD98541FB07 CRC64;
MATTTATTSL LALLLLFLVA LVSAGRDLVG DFLRLPSDSG NGDNVHGTRW AILFAGSSGY
WNYRHQADIC HAYQLLRKGG LKDENIIVFM YDDIAFNSEN PRRGVIINSP NGDDVYKGVP
KDYTGEDVTA HNFYAALLGD KSKLTGGSGK VVNSGPNDHI FIFYSDHGGP GVLGSPAGPY
IYASDLNEVL KKKHASGTYK NLVFYLEACE SGSIFEGLLP EDINVYATTA SNADESSWGT
YCPGEDPSPP PEYSTCLGDL YSVAWMEDSD RHNLRTETLH QQYKLVKERT ISGGLYYGSH
VMQYGDVGLS KDILFHYLGT DPANENLTFV DENSLWSSSK AVNQRDADLV HFWDKFRKAP
EGSPKKNEAR KQVLEVMSHR MHIDDSVELV GKLLFGIEKA PELLNAVRPA GSALVDDWDC
LKTMVRTFET HCGSLSQYGM KHMRSFANMC NVGIKKEQMR EASAQACVTI PANPWSSLQR
GFSA
//
