ID V7CTV3_PHAVU Unreviewed; 548 AA.
AC V7CTV3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=Nucleobase-ascorbate transporter 3 {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHAVU_001G018700g {ECO:0000313|EMBL:ESW32808.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW32808.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the nucleobase:cation symporter-2 (NCS2) (TC
CC 2.A.40) family. {ECO:0000256|ARBA:ARBA00008821}.
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DR EMBL; CM002288; ESW32808.1; -; Genomic_DNA.
DR RefSeq; XP_007160814.1; XM_007160752.1.
DR AlphaFoldDB; V7CTV3; -.
DR STRING; 3885.V7CTV3; -.
DR EnsemblPlants; ESW32808; ESW32808; PHAVU_001G018700g.
DR GeneID; 18640099; -.
DR Gramene; ESW32808; ESW32808; PHAVU_001G018700g.
DR KEGG; pvu:PHAVU_001G018700g; -.
DR eggNOG; KOG1292; Eukaryota.
DR OMA; FMEHIGD; -.
DR OrthoDB; 345287at2759; -.
DR Proteomes; UP000000226; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR GO; GO:0071702; P:organic substance transport; IEA:UniProt.
DR InterPro; IPR006043; NCS2.
DR NCBIfam; NF037981; NCS2_1; 1.
DR PANTHER; PTHR11119:SF29; NUCLEOBASE-ASCORBATE TRANSPORTER 3; 1.
DR PANTHER; PTHR11119; XANTHINE-URACIL / VITAMIN C PERMEASE FAMILY MEMBER; 1.
DR Pfam; PF00860; Xan_ur_permease; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 59..78
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 114..133
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 145..166
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 178..195
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 202..219
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 239..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 382..404
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 410..429
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 441..460
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 480..499
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..26
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 12..26
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 548 AA; 59765 MW; 81A8938671438A99 CRC64;
MGEEHHHAPS PVQAPPSAPP PPNLALSRGP VWNPAEQLLQ LHFCIHSNPS WPEALLLGFQ
HYIVMLGTTV LIATTLVPAM GGDHGDKARV IQSLLFMSGL NTLLQTWFGS RLPTVMGGSF
AFLLPVLSII NDYADRTFPS EHERFIYTIR TIQGSLIVSS FVNIFLGFSK AWGNLTRLFS
PISIVPVVCV VGLGLFSRGF PLLANCVQIG LPMLIVLVIT QQYLKRLLHH AAHHVLERFA
LLLCIAVIWA FAAILTVAGA YNTAKTQTQV SCRTDRSYLM SSAPWIKVPY PFQWGTPIFR
ASHVFGMMGA ALVSSAESTG GFFAAARLSG ATPPPAHVLS RSIGMQGIGM LLEGIFGSVV
GTTVSVENVG LLGLTHIGSR RVVQISCGFM IFFSIFGKFG AFFASIPLPI FAAIYCVLFG
IVAAVGISFI QFANTNSIRN IYVLGLSLFL AISIPQYFVT NTAPDGHGPV KTDGGWFNDI
LNTIFSSSPT VAIIVGILID NTLEGKLKAV DRGLQWWSPF QNRKGDVRND EFYRLPLRIN
EYMPTRFL
//
