ID V7CUE4_PHAVU Unreviewed; 402 AA.
AC V7CUE4;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 32.
DE RecName: Full=Lipase {ECO:0000256|PIRNR:PIRNR000862};
GN ORFNames=PHAVU_001G095000g {ECO:0000313|EMBL:ESW33739.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW33739.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SIMILARITY: Belongs to the AB hydrolase superfamily. Lipase family.
CC {ECO:0000256|ARBA:ARBA00010701, ECO:0000256|PIRNR:PIRNR000862}.
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DR EMBL; CM002288; ESW33739.1; -; Genomic_DNA.
DR RefSeq; XP_007161745.1; XM_007161683.1.
DR AlphaFoldDB; V7CUE4; -.
DR STRING; 3885.V7CUE4; -.
DR EnsemblPlants; ESW33739; ESW33739; PHAVU_001G095000g.
DR GeneID; 18640890; -.
DR Gramene; ESW33739; ESW33739; PHAVU_001G095000g.
DR KEGG; pvu:PHAVU_001G095000g; -.
DR eggNOG; KOG2624; Eukaryota.
DR OMA; WSRRNLY; -.
DR OrthoDB; 1214460at2759; -.
DR Proteomes; UP000000226; Chromosome 1.
DR GO; GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
DR GO; GO:0016042; P:lipid catabolic process; IEA:UniProtKB-KW.
DR Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR InterPro; IPR029058; AB_hydrolase.
DR InterPro; IPR006693; AB_hydrolase_lipase.
DR InterPro; IPR025483; Lipase_euk.
DR PANTHER; PTHR11005; LYSOSOMAL ACID LIPASE-RELATED; 1.
DR PANTHER; PTHR11005:SF99; TRIACYLGLYCEROL LIPASE 2; 1.
DR Pfam; PF04083; Abhydro_lipase; 1.
DR PIRSF; PIRSF000862; Steryl_ester_lip; 1.
DR SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE 3: Inferred from homology;
KW Hydrolase {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid degradation {ECO:0000256|PIRNR:PIRNR000862};
KW Lipid metabolism {ECO:0000256|PIRNR:PIRNR000862};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..24
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 25..402
FT /note="Lipase"
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004756175"
FT DOMAIN 39..97
FT /note="Partial AB-hydrolase lipase"
FT /evidence="ECO:0000259|Pfam:PF04083"
FT ACT_SITE 172
FT /note="Nucleophile"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 342
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
FT ACT_SITE 375
FT /note="Charge relay system"
FT /evidence="ECO:0000256|PIRSR:PIRSR000862-1"
SQ SEQUENCE 402 AA; 44778 MW; ACB755ABD625716A CRC64;
MALQGSMSFA AFTLFLVLTT VSHGRNINPP VYGICSSSVI LHGYKCQEHE VTTNDGYILS
VQRIPEGRAN GSGSRTRKQP VIIQHGVLVD GMTWLLNPPE QDLPLILADN GFDVWIANSR
GTRFSRRHIS LDPSSPAFWN WSWDELVSYD LPAIFNYVFT QTQQKINYVG HSLGTLTALA
SFSEGKLVNQ LKSAALLSPI AYLSHMNTAL GVIAAKSFVG EVTTLFGLAE FNPKGLPVDA
FLKSLCAYPG IDCYDLITEL TGKNCCLNSS TVDIFLRNEP QSTSTKNMVH LAQTVRRGVL
TKFNYVRPDY NIMHYGDVFP PIYNLSNIPH DLPLFISYGG RDALSDARDV QNLLDNLKFH
DVDKLSVQFI KEYAHADYVM GFNAKDFVYN AVISFFNHQV NT
//
