ID V7CWS0_PHAVU Unreviewed; 662 AA.
AC V7CWS0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=VHS domain-containing protein {ECO:0008006|Google:ProtNLM};
GN ORFNames=PHAVU_001G063400g {ECO:0000313|EMBL:ESW33366.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW33366.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004170};
CC Peripheral membrane protein {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the TOM1 family.
CC {ECO:0000256|ARBA:ARBA00007708}.
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DR EMBL; CM002288; ESW33366.1; -; Genomic_DNA.
DR RefSeq; XP_007161372.1; XM_007161310.1.
DR AlphaFoldDB; V7CWS0; -.
DR STRING; 3885.V7CWS0; -.
DR EnsemblPlants; ESW33366; ESW33366; PHAVU_001G063400g.
DR GeneID; 18640558; -.
DR Gramene; ESW33366; ESW33366; PHAVU_001G063400g.
DR KEGG; pvu:PHAVU_001G063400g; -.
DR eggNOG; KOG1087; Eukaryota.
DR OMA; MPANQMA; -.
DR OrthoDB; 472902at2759; -.
DR PhylomeDB; V7CWS0; -.
DR Proteomes; UP000000226; Chromosome 1.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0035091; F:phosphatidylinositol binding; IEA:InterPro.
DR GO; GO:0043130; F:ubiquitin binding; IEA:InterPro.
DR GO; GO:0043328; P:protein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway; IEA:InterPro.
DR CDD; cd14231; GAT_GGA-like_plant; 1.
DR CDD; cd03561; VHS; 1.
DR Gene3D; 1.20.58.160; -; 1.
DR Gene3D; 1.25.40.90; -; 1.
DR InterPro; IPR008942; ENTH_VHS.
DR InterPro; IPR004152; GAT_dom.
DR InterPro; IPR038425; GAT_sf.
DR InterPro; IPR044836; TOL_plant.
DR InterPro; IPR002014; VHS_dom.
DR PANTHER; PTHR45898; TOM1-LIKE PROTEIN; 1.
DR PANTHER; PTHR45898:SF4; TOM1-LIKE PROTEIN 9; 1.
DR Pfam; PF03127; GAT; 1.
DR Pfam; PF00790; VHS; 1.
DR SMART; SM00288; VHS; 1.
DR SUPFAM; SSF48464; ENTH/VHS domain; 1.
DR SUPFAM; SSF89009; GAT-like domain; 1.
DR PROSITE; PS50909; GAT; 1.
DR PROSITE; PS50179; VHS; 1.
PE 3: Inferred from homology;
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT DOMAIN 9..138
FT /note="VHS"
FT /evidence="ECO:0000259|PROSITE:PS50179"
FT DOMAIN 180..268
FT /note="GAT"
FT /evidence="ECO:0000259|PROSITE:PS50909"
FT REGION 142..161
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 392..412
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 461..500
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 461..485
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 662 AA; 71867 MW; 5B478997CC1356E5 CRC64;
MVNSMVERAT SDMLIGPDWA MNIEICDMLN HDPGQAKDVV KGIKKKIGSK NSKVQLLALT
LLETIIKNCG DIVHMHVAER DVLHDMVKMV KKKPDFHVKE KILILVDTWQ EAFGGPRARY
PQYYAAYQEL LRAGAVFPQR SEQSAPVLTP PQTQPLASYP QNIRDSDARQ DTAESSAESE
FPTLSLTEIQ NARGIMDVLA EMLNALDPSN KEGIRQEVIV DLVEQCRTYK QRVVHLVNST
SDESLLCQGL ALNDDLQRVL AKHESISSGT STQNQNHTEN SKSALPGALV DIDAPLVDTG
DTSKQTIERS SSNVQAESQT MNQLLLPAPP ISNGSTIPAK VDPKLDLLSG DDYNSPKADA
SNALVPLGEQ PPANPVSQQK ALVPFDMFSN GNNAPTSVNS QLPQPANVAG QTTPYAPQFQ
QQQTVISQGG FYPNGNVPNA GSAQYEQQSL YTESTGPAWN GQVAQQQQQP PSPVYGSQSS
GSLPPPPWEA QLPDNGSSVA GAQYPYVQNA VHPPGSQTMG NDQGVGMYMQ PNANSHMSGM
NNHVGSNQMG LQPQHMQGVA GPYMGMASHQ MQGGPVMYPQ QMYGNQFMGY GYDQQQRVPY
IERQMYGMSV RDDSALRNSY PVSTTSYAAS GKPSKPEDKL FGDLVDMAKV KPNPTPGRAG
SM
//
