ID V7D0W3_PHAVU Unreviewed; 633 AA.
AC V7D0W3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 42.
DE RecName: Full=non-specific serine/threonine protein kinase {ECO:0000256|ARBA:ARBA00012513};
DE EC=2.7.11.1 {ECO:0000256|ARBA:ARBA00012513};
GN ORFNames=PHAVU_001G222600g {ECO:0000313|EMBL:ESW35288.1};
OS Phaseolus vulgaris (Kidney bean) (French bean).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; fabids; Fabales; Fabaceae; Papilionoideae; 50 kb inversion clade;
OC NPAAA clade; indigoferoid/millettioid clade; Phaseoleae; Phaseolus.
OX NCBI_TaxID=3885 {ECO:0000313|EMBL:ESW35288.1, ECO:0000313|Proteomes:UP000000226};
RN [1] {ECO:0000313|Proteomes:UP000000226}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. G19833 {ECO:0000313|Proteomes:UP000000226};
RX PubMed=24908249; DOI=10.1038/ng.3008;
RA Schmutz J., McClean P.E., Mamidi S., Wu G.A., Cannon S.B., Grimwood J.,
RA Jenkins J., Shu S., Song Q., Chavarro C., Torres-Torres M., Geffroy V.,
RA Moghaddam S.M., Gao D., Abernathy B., Barry K., Blair M., Brick M.A.,
RA Chovatia M., Gepts P., Goodstein D.M., Gonzales M., Hellsten U.,
RA Hyten D.L., Jia G., Kelly J.D., Kudrna D., Lee R., Richard M.M.,
RA Miklas P.N., Osorno J.M., Rodrigues J., Thareau V., Urrea C.A., Wang M.,
RA Yu Y., Zhang M., Wing R.A., Cregan P.B., Rokhsar D.S., Jackson S.A.;
RT "A reference genome for common bean and genome-wide analysis of dual
RT domestications.";
RL Nat. Genet. 46:707-713(2014).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-
CC [protein]; Xref=Rhea:RHEA:17989, Rhea:RHEA-COMP:9863, Rhea:RHEA-
CC COMP:11604, ChEBI:CHEBI:15378, ChEBI:CHEBI:29999, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:83421, ChEBI:CHEBI:456216; EC=2.7.11.1;
CC Evidence={ECO:0000256|ARBA:ARBA00001433};
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-
CC threonyl-[protein]; Xref=Rhea:RHEA:46608, Rhea:RHEA-COMP:11060,
CC Rhea:RHEA-COMP:11605, ChEBI:CHEBI:15378, ChEBI:CHEBI:30013,
CC ChEBI:CHEBI:30616, ChEBI:CHEBI:61977, ChEBI:CHEBI:456216;
CC EC=2.7.11.1; Evidence={ECO:0000256|ARBA:ARBA00000775};
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DR EMBL; CM002288; ESW35288.1; -; Genomic_DNA.
DR RefSeq; XP_007163294.1; XM_007163232.1.
DR AlphaFoldDB; V7D0W3; -.
DR STRING; 3885.V7D0W3; -.
DR EnsemblPlants; ESW35288; ESW35288; PHAVU_001G222600g.
DR GeneID; 18642208; -.
DR Gramene; ESW35288; ESW35288; PHAVU_001G222600g.
DR KEGG; pvu:PHAVU_001G222600g; -.
DR eggNOG; KOG2464; Eukaryota.
DR OMA; DYWEGSF; -.
DR OrthoDB; 5491350at2759; -.
DR Proteomes; UP000000226; Chromosome 1.
DR GO; GO:0005737; C:cytoplasm; IEA:EnsemblPlants.
DR GO; GO:0005634; C:nucleus; IEA:EnsemblPlants.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0035402; F:histone H3T11 kinase activity; IEA:EnsemblPlants.
DR GO; GO:0072354; F:histone H3T3 kinase activity; IEA:EnsemblPlants.
DR GO; GO:0000278; P:mitotic cell cycle; IEA:EnsemblPlants.
DR GO; GO:0016310; P:phosphorylation; IEA:UniProtKB-KW.
DR Gene3D; 1.10.510.10; Transferase(Phosphotransferase) domain 1; 1.
DR InterPro; IPR024604; GSG2_C.
DR InterPro; IPR011009; Kinase-like_dom_sf.
DR InterPro; IPR000719; Prot_kinase_dom.
DR PANTHER; PTHR24419; INTERLEUKIN-1 RECEPTOR-ASSOCIATED KINASE; 1.
DR PANTHER; PTHR24419:SF18; SERINE_THREONINE-PROTEIN KINASE HASPIN; 1.
DR Pfam; PF12330; Haspin_kinase; 1.
DR SMART; SM01331; DUF3635; 1.
DR SMART; SM00220; S_TKc; 1.
DR SUPFAM; SSF56112; Protein kinase-like (PK-like); 1.
DR PROSITE; PS50011; PROTEIN_KINASE_DOM; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777};
KW Reference proteome {ECO:0000313|Proteomes:UP000000226};
KW Serine/threonine-protein kinase {ECO:0000256|ARBA:ARBA00022527};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 318..633
FT /note="Protein kinase"
FT /evidence="ECO:0000259|PROSITE:PS50011"
FT REGION 1..27
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 55..92
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 110..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 633 AA; 71337 MW; 90B2EEACED574A4A CRC64;
MNTNFEAVKG TGFPLPRCPS SNANAQSSPL DLWSEIIADE PPQPQRIDVV YRRRHPRNPN
NHTNSNPFDP PLPRPTRPSL DPNKRVSWNR SLSTRGRTSI AVGASMVYQP QLKKDKRKGK
PALPKGKLVQ PPNVEKERLY FEEVDAFELL EESPSPKKNT WITDDLKQEG PMPTICSRLE
KWLHSKRLNS SCGPSSTLSK ILDASSTRLE GIQDIDFSTP ELRTLEPTEK SNSLQTIKTG
DRKTSVENDI HLQQTNEKML FAQSGEGCEN IDAAVKKLSL ISTSSSIDND HISPFSALLA
ICGQSAPSLL QDIFSSGSKT IVKVGEGTFG EAFKVNNYVC KIVPFDGDFR VNGEIQKKSE
ELLEEVLLCQ TLNRLRGKAG ASDNLSSAFI DCIEFRVCQG PYDAELIRAW EDWDLKHGSE
NDHPKEFPDK QCYVVFVQEH GGKDLEGFAL LNFDEARALL AQVTAGLAVA ESAFEFEHRD
LHWGNILVGR SDSEALQFTL DGRRMLVKTS GLIISIIDFT LSRINTGDRI LYLDLSCDPD
LFKGPKGDKQ SETYRRMKEV TEDWWEGSCP KTNVLWLIYL VDILLMKKSF ERTSKHERDL
RSFKKRLDKY DSSKEAILDP FFTDLFIESD AKV
//
