ID V7EIX9_9RHOB Unreviewed; 551 AA.
AC V7EIX9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Radical SAM protein {ECO:0000313|EMBL:ESW60082.1};
GN ORFNames=Q27BPR15_13865 {ECO:0000313|EMBL:ESW60082.1};
OS Rhodobacter sp. CACIA14H1.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC Paracoccaceae; Rhodobacter.
OX NCBI_TaxID=1408890 {ECO:0000313|EMBL:ESW60082.1, ECO:0000313|Proteomes:UP000018503};
RN [1] {ECO:0000313|EMBL:ESW60082.1, ECO:0000313|Proteomes:UP000018503}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=24435858;
RA Lima A.R., Siqueira A.S., Dos Santos B.G., da Silva F.D., Inada D.T.,
RA Lima C.P., Cardoso J.F., Vianez-Junior J.L., Nunes M.R., Goncalves E.C.;
RT "Draft Genome Sequence of Rhodobacter sp. Strain CACIA 14H1, a
RT Heterotrophic Bacterium Obtained from a Nonaxenic Culture of a Cyanobium
RT Species.";
RL Genome Announc. 2:e01116-13(2014).
CC -!- COFACTOR:
CC Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC Evidence={ECO:0000256|ARBA:ARBA00001966};
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ESW60082.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AYNO01000107; ESW60082.1; -; Genomic_DNA.
DR AlphaFoldDB; V7EIX9; -.
DR STRING; 1408890.Q27BPR15_13865; -.
DR PATRIC; fig|449393.3.peg.2782; -.
DR Proteomes; UP000018503; Unassembled WGS sequence.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0031419; F:cobalamin binding; IEA:InterPro.
DR GO; GO:0051536; F:iron-sulfur cluster binding; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:InterPro.
DR CDD; cd01335; Radical_SAM; 1.
DR CDD; cd02068; radical_SAM_B12_BD; 1.
DR Gene3D; 3.40.50.280; Cobalamin-binding domain; 1.
DR Gene3D; 3.80.30.20; tm_1862 like domain; 1.
DR InterPro; IPR006158; Cobalamin-bd.
DR InterPro; IPR006638; Elp3/MiaA/NifB-like_rSAM.
DR InterPro; IPR034466; Methyltransferase_Class_B.
DR InterPro; IPR007197; rSAM.
DR InterPro; IPR023404; rSAM_horseshoe.
DR NCBIfam; TIGR02026; BchE; 1.
DR PANTHER; PTHR43409:SF7; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE; 1.
DR PANTHER; PTHR43409; ANAEROBIC MAGNESIUM-PROTOPORPHYRIN IX MONOMETHYL ESTER CYCLASE-RELATED; 1.
DR Pfam; PF02310; B12-binding; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDF00302; anaerobic_magnesium-protoporph; 1.
DR SFLD; SFLDG01082; B12-binding_domain_containing; 1.
DR SFLD; SFLDG01123; methyltransferase_(Class_B); 1.
DR SMART; SM00729; Elp3; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51332; B12_BINDING; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW 4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW Iron {ECO:0000256|ARBA:ARBA00022485};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00022485};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW Reference proteome {ECO:0000313|Proteomes:UP000018503}.
FT DOMAIN 9..143
FT /note="B12-binding"
FT /evidence="ECO:0000259|PROSITE:PS51332"
FT DOMAIN 190..417
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 551 AA; 63152 MW; CE45C51D62405D05 CRC64;
MRIVFIHPNY HSGGAEIAGN WPPAWVAYLT GHLRRAGFDD IHFIDAMTHH IGPEELRARL
AALRPDVVGL TAITPAIYEA EECLRIAQEV CPDALRVLGG IHATFMFRQV LEEAPWVDVI
VRGEGEEILV NLMEAVRDGR WPAERRKIRG LAFKDGDEIV ATQAASTVKD LDAIDPDWSI
LDWSKYVYVP LGVKVAIPNM ARGCPFTCSF CSQWKFWRDY RVRDPRRVAD EIERLVTDHG
VGFFILADEE PTINKKKFVE FCQELIDRGL NERVTWGINT RVTDIYRDRD LLKFYRKAGL
VHVSLGTEAA AQLKLDLFNK ETTVAENKEA IRLLREADIF VEAQFIVGLE NETKETLEET
FQMAWDWQPD LANWSMYTPW PFTPLFQEIR DQVEVFDFSK YNFVTPIMKP AALTRGELLD
GVMKNYRRFY MRKALFHYPW RGTGFRRRYL LGCLKAFLKA GVGRTFYDLG KAGYWGPQTK
GKVDFHFDET RKIADAQMAD WEASADRAAK AAERRAAVKA QMAGRAEERR AFRMPEVSAC
GGGKQQMDEE A
//
