ID V7HZI8_9LACO Unreviewed; 389 AA.
AC V7HZI8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=Putative N6-adenine-specific DNA methylase {ECO:0000313|EMBL:ETA74623.1};
GN ORFNames=LEQ_1813 {ECO:0000313|EMBL:ETA74623.1};
OS Ligilactobacillus equi DPC 6820.
OC Bacteria; Bacillota; Bacilli; Lactobacillales; Lactobacillaceae;
OC Ligilactobacillus.
OX NCBI_TaxID=1392007 {ECO:0000313|EMBL:ETA74623.1, ECO:0000313|Proteomes:UP000018559};
RN [1] {ECO:0000313|EMBL:ETA74623.1, ECO:0000313|Proteomes:UP000018559}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DPC 6820 {ECO:0000313|EMBL:ETA74623.1,
RC ECO:0000313|Proteomes:UP000018559};
RX PubMed=24435863;
RA O'Donnell M.M., Harris H.M., O'Toole P.W., Ross R.P.;
RT "The Genome of the Predominant Equine Lactobacillus Species, Lactobacillus
RT equi, Is Reflective of Its Lifestyle Adaptations to an Herbivorous Host.";
RL Genome Announc. 2:e01155-e01113(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETA74623.1}.
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DR EMBL; AWWH01000055; ETA74623.1; -; Genomic_DNA.
DR AlphaFoldDB; V7HZI8; -.
DR PATRIC; fig|1392007.3.peg.568; -.
DR Proteomes; UP000018559; Unassembled WGS sequence.
DR GO; GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
DR GO; GO:0003723; F:RNA binding; IEA:UniProtKB-UniRule.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR GO; GO:0034470; P:ncRNA processing; IEA:UniProt.
DR GO; GO:0009451; P:RNA modification; IEA:UniProt.
DR CDD; cd02440; AdoMet_MTases; 1.
DR CDD; cd11715; THUMP_AdoMetMT; 1.
DR Gene3D; 3.30.2130.30; -; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR002052; DNA_methylase_N6_adenine_CS.
DR InterPro; IPR000241; RlmKL-like_Mtase.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR InterPro; IPR004114; THUMP_dom.
DR PANTHER; PTHR47313; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K/L; 1.
DR PANTHER; PTHR47313:SF1; RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE K_L; 1.
DR Pfam; PF02926; THUMP; 1.
DR Pfam; PF01170; UPF0020; 1.
DR SMART; SM00981; THUMP; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS00092; N6_MTASE; 1.
DR PROSITE; PS51165; THUMP; 1.
DR PROSITE; PS01261; UPF0020; 1.
PE 4: Predicted;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603,
KW ECO:0000313|EMBL:ETA74623.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000018559};
KW RNA-binding {ECO:0000256|PROSITE-ProRule:PRU00529};
KW Transferase {ECO:0000256|ARBA:ARBA00022603, ECO:0000313|EMBL:ETA74623.1}.
FT DOMAIN 56..167
FT /note="THUMP"
FT /evidence="ECO:0000259|PROSITE:PS51165"
SQ SEQUENCE 389 AA; 44068 MW; D176BB9B0221AD3D CRC64;
MLFYLWKENF MTKKFKLIAT AAAGIEAIVG NELRHLGYEK VQVENSRVRF EGDVTDIIKT
NLWLRTADRV KIVLAEFEAR TFEELFQGTK AVAWDELLPM DAAFPVSGKS QKSALHNVPS
VQAITKKAIV NQLSEAYHRR TRLPETGALY PIEVAINKDK VMLTLDTTGS SLFKRGYRVA
KGGAPMKENM AAALILLAHW YPEKPFVDPV CGSGTLPIEA AMIGYNIAPG LMRSFAFENW
SFVTPTLVKQ IKNEAKAQAN FDVELDITGY DIDGSMIEIA KENARAANLE DSITFKQQAV
KDFKTDKING VVVANPPYGE RLSDQESVRQ LYKQMGQVFL PHESWSEYIL TSDLEFEKYY
GKKASKKRKL YNGSLRTDYF QYWGKRIRN
//
