ID V8C7E3_9HELI Unreviewed; 436 AA.
AC V8C7E3;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 40.
DE RecName: Full=Radical SAM core domain-containing protein {ECO:0000259|PROSITE:PS51918};
GN ORFNames=HMPREF2086_01098 {ECO:0000313|EMBL:ETD23299.1};
OS Helicobacter macacae MIT 99-5501.
OC Bacteria; Campylobacterota; Epsilonproteobacteria; Campylobacterales;
OC Helicobacteraceae; Helicobacter.
OX NCBI_TaxID=1357400 {ECO:0000313|EMBL:ETD23299.1, ECO:0000313|Proteomes:UP000018731};
RN [1] {ECO:0000313|EMBL:ETD23299.1, ECO:0000313|Proteomes:UP000018731}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 99-5501 {ECO:0000313|EMBL:ETD23299.1,
RC ECO:0000313|Proteomes:UP000018731};
RX PubMed=25212613;
RA Shen Z., Sheh A., Young S.K., Abouelliel A., Ward D.V., Earl A.M.,
RA Fox J.G.;
RT "Draft genome sequences of six enterohepatic helicobacter species isolated
RT from humans and one from rhesus macaques.";
RL Genome Announc. 2:e00857-e00814(2014).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETD23299.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZJI01000005; ETD23299.1; -; Genomic_DNA.
DR RefSeq; WP_023927824.1; NZ_KI669454.1.
DR AlphaFoldDB; V8C7E3; -.
DR STRING; 1357400.HMPREF2086_01098; -.
DR PATRIC; fig|1357400.3.peg.1489; -.
DR eggNOG; COG0535; Bacteria.
DR HOGENOM; CLU_009273_4_4_7; -.
DR Proteomes; UP000018731; Unassembled WGS sequence.
DR GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR GO; GO:0003824; F:catalytic activity; IEA:InterPro.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd01335; Radical_SAM; 1.
DR Gene3D; 3.20.20.70; Aldolase class I; 1.
DR InterPro; IPR023885; 4Fe4S-binding_SPASM_dom.
DR InterPro; IPR013785; Aldolase_TIM.
DR InterPro; IPR007197; rSAM.
DR NCBIfam; TIGR04085; rSAM_more_4Fe4S; 1.
DR PANTHER; PTHR11228:SF35; MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A-RELATED; 1.
DR PANTHER; PTHR11228; RADICAL SAM DOMAIN PROTEIN; 1.
DR Pfam; PF13353; Fer4_12; 1.
DR Pfam; PF04055; Radical_SAM; 1.
DR SFLD; SFLDG01386; main_SPASM_domain-containing; 1.
DR SFLD; SFLDG01067; SPASM/twitch_domain_containing; 1.
DR SUPFAM; SSF102114; Radical SAM enzymes; 1.
DR PROSITE; PS51918; RADICAL_SAM; 1.
PE 4: Predicted;
KW Iron {ECO:0000256|ARBA:ARBA00023004};
KW Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018731};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691}.
FT DOMAIN 92..321
FT /note="Radical SAM core"
FT /evidence="ECO:0000259|PROSITE:PS51918"
SQ SEQUENCE 436 AA; 49287 MW; 6198387CBAD3A952 CRC64;
MTTSTNQINE NDILPLPKTL EFCKINNEML VIAPGCGNII GLFNENQVEI FENLRQHSII
DTEKMAKNEA DFNFVVAQIL DREFFDSPLD MYDEYDTVQI YLTNACNLSC PHCYVNAGVA
NKNELEANQW FAVLDELAKN GTKEVIFSGG EILLYKKCIE VIKYAKSLGF IVSLKSNGTL
WSKEQISDVA PFIDDIQISI DGINEEMNAK VRGANSFQKA LFCVEQFLKC GTKVIIATTP
TYANINEIEA GFVAFATDLL KKYGKNLSFI VSQKMLGGRG IAMKFDDESK HYAKTTDSLM
EQIYPNYKLK NLAISIEKKQ RVRNCGYGNL TFASNGNIYL CNRIDELRPF ANINDDLKEV
LHKAKEFNAK SSVDFVNPCK NCSVRYICGG GCRIDEYNFK GRQELLGKEL VKECSENFRI
KFKQSLLNGL KYVYAI
//
