ID V8NBH8_OPHHA Unreviewed; 177 AA.
AC V8NBH8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE SubName: Full=Atrial natriuretic peptide-converting enzyme {ECO:0000313|EMBL:ETE59445.1};
DE Flags: Fragment;
GN Name=CORIN {ECO:0000313|EMBL:ETE59445.1};
GN ORFNames=L345_14825 {ECO:0000313|EMBL:ETE59445.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE59445.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE59445.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE59445.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|PROSITE-ProRule:PRU00124}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE59445.1}.
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DR EMBL; AZIM01005573; ETE59445.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NBH8; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR CDD; cd00112; LDLa; 4.
DR Gene3D; 4.10.400.10; Low-density Lipoprotein Receptor; 4.
DR InterPro; IPR036055; LDL_receptor-like_sf.
DR InterPro; IPR023415; LDLR_class-A_CS.
DR InterPro; IPR002172; LDrepeatLR_classA_rpt.
DR PANTHER; PTHR24270:SF2; ATRIAL NATRIURETIC PEPTIDE-CONVERTING ENZYME; 1.
DR PANTHER; PTHR24270; LOW-DENSITY LIPOPROTEIN RECEPTOR-RELATED; 1.
DR Pfam; PF00057; Ldl_recept_a; 4.
DR PRINTS; PR00261; LDLRECEPTOR.
DR SMART; SM00192; LDLa; 4.
DR SUPFAM; SSF57424; LDL receptor-like module; 4.
DR PROSITE; PS01209; LDLRA_1; 1.
DR PROSITE; PS50068; LDLRA_2; 4.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157, ECO:0000256|PROSITE-
KW ProRule:PRU00124}; Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DISULFID 10..28
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 22..37
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 39..51
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 46..64
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 58..73
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 83..101
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 95..110
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 120..138
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT DISULFID 132..147
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00124"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE59445.1"
FT NON_TER 177
FT /evidence="ECO:0000313|EMBL:ETE59445.1"
SQ SEQUENCE 177 AA; 19686 MW; 80C69E2B544A6B90 CRC64;
LCEEDENFLC RSGICIPRIL QCNGFNDCDD WSDEMHCNCS EELFRCDTGR CLNYTFVCDG
YDDCGDLSDE QNCDCNPVTQ HQCGDGRCIT MDWICDGDPD CLDKSDETNC SCHSQGLVEC
RNGQCVPSTF QCDGDNDCKD GSDEENCGGS QRVCHERDQK CNSTLCPDSC GHSPPLM
//
