ID V8NBW2_OPHHA Unreviewed; 346 AA.
AC V8NBW2;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 22-FEB-2023, entry version 31.
DE SubName: Full=Keratin, type I cytoskeletal 10 {ECO:0000313|EMBL:ETE59128.1};
DE Flags: Fragment;
GN Name=KRT10 {ECO:0000313|EMBL:ETE59128.1};
GN ORFNames=L345_15144 {ECO:0000313|EMBL:ETE59128.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE59128.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE59128.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE59128.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE59128.1}.
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DR EMBL; AZIM01005851; ETE59128.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NBW2; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0005882; C:intermediate filament; IEA:UniProtKB-KW.
DR GO; GO:0005198; F:structural molecule activity; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR002957; Keratin_I.
DR PANTHER; PTHR23239; INTERMEDIATE FILAMENT; 1.
DR PANTHER; PTHR23239:SF96; KERATIN, TYPE I CYTOSKELETAL 9; 1.
DR Pfam; PF00038; Filament; 1.
DR PRINTS; PR01248; TYPE1KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 1..313
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 108..298
FT /evidence="ECO:0000256|SAM:Coils"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE59128.1"
FT NON_TER 346
FT /evidence="ECO:0000313|EMBL:ETE59128.1"
SQ SEQUENCE 346 AA; 39661 MW; D1A4E32764CBF90A CRC64;
MQNLNDRLAN YLDQVKRLED ENCQLEIWIK EWYQKHGDIG PDKDYGHYYQ EIDQLYSELI
AETDDYNKIL LNIDNTRMTA EDFKMKYNTE AGLRQNVEAD INGLRPLLDQ LTLAKSDLEM
QFESLKEELI CLKKNHEETL RGLRGQRGHG DVSVEVNAAP GQDLKQRLDQ LRCEYETLIE
QNRKEVEAWY ESKASEMEEV RQQVSTSDQE ITSSNHQLSE LRREYQTLEI ELQSQISMIQ
SLQTNLEDTE RRYNMQLQQI QAMIEPVEGE LTSIRCEIES QNQEYQLLLG IKTRLEQEIC
QYRRLLEEGQ QEIGSGGYGG GYGGGRRGGG SISGGGVCVG GGVSGG
//
