ID V8NIF7_OPHHA Unreviewed; 516 AA.
AC V8NIF7;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 19.
DE SubName: Full=Membrane-associated transporter protein {ECO:0000313|EMBL:ETE61865.1};
DE Flags: Fragment;
GN Name=SLC45A2 {ECO:0000313|EMBL:ETE61865.1};
GN ORFNames=L345_12382 {ECO:0000313|EMBL:ETE61865.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE61865.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE61865.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE61865.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the glycoside-pentoside-hexuronide (GPH) cation
CC symporter transporter (TC 2.A.2) family.
CC {ECO:0000256|ARBA:ARBA00038193}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE61865.1}.
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DR EMBL; AZIM01003606; ETE61865.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NIF7; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR CDD; cd17313; MFS_SLC45_SUC; 1.
DR Gene3D; 1.20.1250.20; MFS general substrate transporter like domains; 1.
DR InterPro; IPR036259; MFS_trans_sf.
DR PANTHER; PTHR19432:SF34; MEMBRANE-ASSOCIATED TRANSPORTER PROTEIN; 1.
DR PANTHER; PTHR19432; SUGAR TRANSPORTER; 1.
DR SUPFAM; SSF103473; MFS general substrate transporter; 2.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 46..65
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 71..91
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 103..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 136..155
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 242..261
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 402..421
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 427..445
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 466..488
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 494..515
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE61865.1"
FT NON_TER 516
FT /evidence="ECO:0000313|EMBL:ETE61865.1"
SQ SEQUENCE 516 AA; 56850 MW; E70B9D52305B9203 CRC64;
MGPLSRKEEI VFKPFPGKDP FKPVKPSKKR TGQLIMHSTI MFGREFCYAV EAAFVTPVLL
TVGLPKSLYS FVWLISPILG FLLQPVVGSV SDRCTSRWGK RRPFILILGL LMLLGMALYL
NGDAVISVLV VDRGTWKMWA IIITMLGVVL FDFAADFIDG PIKAYLFDVC THQDKQKGLH
YHALLTVSYE MEKNTPVYDL KRFQIHHPEA KNKLGLGGAL GYLTGAIDWG ATILGKYLGS
EFHVMFFFGA LVFLLCLTVH LCSIPEAPLV DTSGETKVLV KNSQPDQYGA IERVKNNSEC
SEIQISPKEE KLTTKADSQV QRQITIMSLL EALLNMPPHY RSLCLSHLMG WTAFLSNMLF
FTDFMGQIVF EGDPYAPHNS TAYLTYKRDV QRALLPFLGL KGLYFVGYLL FGLGTGFIGL
FPKVHPTLTL CSLFGVMSST LYTIPFNLNQ KHDEAVDSTR GKGIDCAALT CMVQLAQIIV
GVGLGLLVSA AGSVVVVVIS ASAVALLGSC FVALFV
//
