ID   V8NJ78_OPHHA            Unreviewed;       774 AA.
AC   V8NJ78;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Multimerin-2 {ECO:0000313|EMBL:ETE62145.1};
DE   Flags: Fragment;
GN   Name=Mmrn2 {ECO:0000313|EMBL:ETE62145.1};
GN   ORFNames=L345_12103 {ECO:0000313|EMBL:ETE62145.1};
OS   Ophiophagus hannah (King cobra) (Naja hannah).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX   NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE62145.1, ECO:0000313|Proteomes:UP000018936};
RN   [1] {ECO:0000313|EMBL:ETE62145.1, ECO:0000313|Proteomes:UP000018936}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Blood {ECO:0000313|EMBL:ETE62145.1};
RX   PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA   Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA   McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA   Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA   de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA   Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA   Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA   Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT   "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT   snake venom system.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETE62145.1}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; AZIM01003425; ETE62145.1; -; Genomic_DNA.
DR   AlphaFoldDB; V8NJ78; -.
DR   Proteomes; UP000018936; Unassembled WGS sequence.
DR   InterPro; IPR011489; EMI_domain.
DR   Pfam; PF07546; EMI; 1.
DR   PROSITE; PS51041; EMI; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Disulfide bond {ECO:0000256|ARBA:ARBA00023157};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..17
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           18..774
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004770863"
FT   DOMAIN          77..153
FT                   /note="EMI"
FT                   /evidence="ECO:0000259|PROSITE:PS51041"
FT   REGION          20..50
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          590..613
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          735..774
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          292..413
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        34..48
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ETE62145.1"
FT   NON_TER         774
FT                   /evidence="ECO:0000313|EMBL:ETE62145.1"
SQ   SEQUENCE   774 AA;  89847 MW;  023E9EA14174B822 CRC64;
     MLPTLLLLCG AVGLLKSDPH SRHPGYYHQR PGPEVPQMPA PPPPSSPAEE FWRRESIQGE
     TEADLEESYP ASREFRNENW CSSVQYRHAT FIAVCKTEKY IIRSQQPCPN GTPDCQKIMY
     RTALKPVYKI KEKVVSFLDW KCCPGYVGKD CEQYGKNTSL KLQQMLFLHI NGFLKEHFNP
     IWASFNKSLQ DLSVAVQNLS QSVEANRKSI EQFQESSVPR KDFQELGTKF ESKVQANVLR
     ADQMKREMDH HNYLQQAVIH YNLTMIKADT DLKLKRHHKL QQSFLFALNN SLADMRQEQN
     KLRGELEILN RNVAIFPRQS GNQNGVFADI DIQSFNQTLE KHARELKTLY EESEKDYEEL
     TDSITRLKDS SKRDIEDFRV RLIEGSLMID EYREDVEKRI FALNNSLADI QENYWSLQKS
     MKTCCCEDQP SSTHVEDLNN TTQMHGEHLK HLEARLKDLA AAFPLIHQSL DFQQEQSWKL
     QDGLSLLKNH SDISSEEVNM LKKADEKMRD HVTYLNSSFN SLLVDALRHE KALEVLLGEE
     ILEHLYEEEV VLPTDQFPVM NIKLISDHLK KQSMALENFK KRIDFLEADH EDNPHDHKSL
     KEPDTEKQTD LNPQHGRVEY MEPNHEAFME DALDNPAYHD ITTLKREIGH LTKEMKKFES
     QWDYIHSCCN QTKSNLGDLL GVSVKAVKED LVSAKKNFEE HLVIFHKLFG NSKELAASNV
     SLDVAKLQLL MSRKTRKHLK EKEQQNMREK KEVHGHREAT VNGRNKINAE TLER
//