ID V8NM75_OPHHA Unreviewed; 332 AA.
AC V8NM75;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=Protein YIPF {ECO:0000256|RuleBase:RU361264};
GN Name=Yipf2 {ECO:0000313|EMBL:ETE63389.1};
GN ORFNames=L345_10849 {ECO:0000313|EMBL:ETE63389.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE63389.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE63389.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE63389.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBCELLULAR LOCATION: Endosome membrane
CC {ECO:0000256|ARBA:ARBA00004608}. Golgi apparatus membrane
CC {ECO:0000256|RuleBase:RU361264}; Multi-pass membrane protein
CC {ECO:0000256|RuleBase:RU361264}. Golgi apparatus, trans-Golgi network
CC membrane {ECO:0000256|ARBA:ARBA00004198}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the YIP1 family. {ECO:0000256|ARBA:ARBA00010596,
CC ECO:0000256|RuleBase:RU361264}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE63389.1}.
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DR EMBL; AZIM01002769; ETE63389.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NM75; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0031267; F:small GTPase binding; IEA:InterPro.
DR GO; GO:0016192; P:vesicle-mediated transport; IEA:InterPro.
DR InterPro; IPR006977; Yip1_dom.
DR InterPro; IPR039765; Yip5/YIPF1/YIPF2.
DR PANTHER; PTHR12822:SF3; PROTEIN YIPF2; 1.
DR PANTHER; PTHR12822; UNCHARACTERIZED; 1.
DR Pfam; PF04893; Yip1; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361264};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU361264};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU361264}.
FT TRANSMEM 114..137
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361264"
FT TRANSMEM 157..177
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361264"
FT TRANSMEM 189..215
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361264"
FT TRANSMEM 221..244
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361264"
FT TRANSMEM 251..269
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361264"
FT DOMAIN 97..267
FT /note="Yip1"
FT /evidence="ECO:0000259|Pfam:PF04893"
SQ SEQUENCE 332 AA; 37815 MW; 67F61364C1317F66 CRC64;
MAASDELKFR EFNEAMDLLA GNADATTPSI SESQSHVTLN MSSSCNEEYE PDEEDDKTEL
LSFQKKQSSF WTFEYYQAFF NVDTYQVLDR IKGSLLPLPG KNFVWHHLQN NPDLYGPFWI
CATLVFTLAI SGNLSYFLEK RGSSSFHYSP QFHKVTIAGI VIYCYAWLVP LGLWGYLHWR
KGAHVTTDVY SFLEMVCIYG YSLFVYIPTA VLWLIPIPWL QWLLIIVAIG LSGSVLVLTF
WPVIRSDSKP AACVIMAIIV SLHILLAIGC KTSILNIQYQ GRKNRPLKTP YSRDIKTLTR
KKILQVGQAK SYITISKFIV LLLPGRAHQQ FA
//
