ID V8NNV0_OPHHA Unreviewed; 415 AA.
AC V8NNV0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE RecName: Full=Glutamate-rich WD repeat-containing protein 1 {ECO:0000256|ARBA:ARBA00040876};
GN Name=Grwd1 {ECO:0000313|EMBL:ETE63959.1};
GN ORFNames=L345_10276 {ECO:0000313|EMBL:ETE63959.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE63959.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE63959.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE63959.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE63959.1}.
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DR EMBL; AZIM01002477; ETE63959.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NNV0; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 1.
DR InterPro; IPR020472; G-protein_beta_WD-40_rep.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR019775; WD40_repeat_CS.
DR InterPro; IPR036322; WD40_repeat_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR45903; GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR45903:SF1; GLUTAMATE-RICH WD REPEAT-CONTAINING PROTEIN 1; 1.
DR Pfam; PF00400; WD40; 3.
DR PRINTS; PR00320; GPROTEINBRPT.
DR SMART; SM00320; WD40; 6.
DR SUPFAM; SSF50978; WD40 repeat-like; 1.
DR PROSITE; PS00678; WD_REPEATS_1; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 3.
DR PROSITE; PS50294; WD_REPEATS_REGION; 3.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW WD repeat {ECO:0000256|ARBA:ARBA00022574, ECO:0000256|PROSITE-
KW ProRule:PRU00221}.
FT REPEAT 228..263
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 275..309
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REPEAT 320..354
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 1..60
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..110
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 415 AA; 45799 MW; 07646280B6E2997F CRC64;
MEESCTWEEE NPASSSRSSG SSDEMEDMEM EEKEEKQQGK SQAGAYVPGK GPPPAPGEEL
VMDEGAYRLY HRAGTVMKMH NLHGTKSACK NSSESESSSE SEDDDEDKKP QLELAMVPHY
GGINRLRVTE LGETQVVAAW SEKGQVDIYD LQRLLVAVSD PQAMAVFLRE EQAKIKPIFS
FTGHMSEGFA MDWSPKKPGT LLTGDCNKNI HLWTPKEDGS WFVDQRPFTA HTASVEDIQW
SPNEATVFAS CSADASIRVW DTRAAPGKAC MLTTSKAHDA DVNVISWNRN EPFIVSGGDD
GILRIWDLRQ FQKGSAVATF KQHTAPITSV EWHPTDSGVF AASGADDQVT QWDLAVERDE
EGEAEDPALA TIPPQLLFVH QGENDIKELH WHPQCPGTLI TTALSGFNIF RTISV
//
