ID V8NPP1_OPHHA Unreviewed; 250 AA.
AC V8NPP1;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 20.
DE SubName: Full=Origin recognition complex subunit 5 {ECO:0000313|EMBL:ETE64259.1};
DE Flags: Fragment;
GN Name=ORC5 {ECO:0000313|EMBL:ETE64259.1};
GN ORFNames=L345_09974 {ECO:0000313|EMBL:ETE64259.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE64259.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE64259.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE64259.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE64259.1}.
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DR EMBL; AZIM01002327; ETE64259.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NPP1; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0000808; C:origin recognition complex; IEA:InterPro.
DR GO; GO:0006260; P:DNA replication; IEA:UniProtKB-KW.
DR InterPro; IPR020796; ORC5.
DR InterPro; IPR047088; ORC5_C.
DR InterPro; IPR048866; ORC5_lid.
DR PANTHER; PTHR12705; ORIGIN RECOGNITION COMPLEX SUBUNIT 5; 1.
DR PANTHER; PTHR12705:SF0; ORIGIN RECOGNITION COMPLEX SUBUNIT 5; 1.
DR Pfam; PF14630; ORC5_C; 1.
DR Pfam; PF21639; ORC5_lid; 1.
PE 4: Predicted;
KW DNA replication {ECO:0000256|ARBA:ARBA00022705};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 19..86
FT /note="ORC5 lid"
FT /evidence="ECO:0000259|Pfam:PF21639"
FT DOMAIN 117..246
FT /note="Origin recognition complex subunit 5 C-terminal"
FT /evidence="ECO:0000259|Pfam:PF14630"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE64259.1"
SQ SEQUENCE 250 AA; 29036 MW; D22A081EC6046464 CRC64;
HLQKILSHDH PPEYSFDFYA AYINILLGVF YPVCRDLKEL QHLAALNFSK YCEPVVQGEA
NERDTRRLWK NIESHLKKAM QTVYLREISS SQWERLQQDN GEPGQVKGLS AHAHVELPYY
SKFLLIAAYL ASYNPARTDK RFFVKHHGKI RKVNFQKKHE KTSNHLLGPK PFPLDRLLAI
LYSIVDSRIP PTANIFSQIT SLVTLQLLTL IGHDDQFNGP RYKCAVSLDF IRAISRTVNF
DITKYLYDFL
//
