ID   V8NQQ3_OPHHA            Unreviewed;       712 AA.
AC   V8NQQ3;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Myoferlin {ECO:0000313|EMBL:ETE64296.1};
DE   Flags: Fragment;
GN   Name=myof {ECO:0000313|EMBL:ETE64296.1};
GN   ORFNames=L345_09933 {ECO:0000313|EMBL:ETE64296.1};
OS   Ophiophagus hannah (King cobra) (Naja hannah).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX   NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE64296.1, ECO:0000313|Proteomes:UP000018936};
RN   [1] {ECO:0000313|EMBL:ETE64296.1, ECO:0000313|Proteomes:UP000018936}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Blood {ECO:0000313|EMBL:ETE64296.1};
RX   PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA   Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA   McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA   Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA   de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA   Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA   Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA   Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT   "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT   snake venom system.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETE64296.1}.
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DR   EMBL; AZIM01002312; ETE64296.1; -; Genomic_DNA.
DR   AlphaFoldDB; V8NQQ3; -.
DR   Proteomes; UP000018936; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProt.
DR   GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:UniProt.
DR   GO; GO:0016020; C:membrane; IEA:InterPro.
DR   GO; GO:0016043; P:cellular component organization; IEA:UniProt.
DR   CDD; cd04017; C2D_Ferlin; 1.
DR   Gene3D; 2.60.40.150; C2 domain; 1.
DR   InterPro; IPR000008; C2_dom.
DR   InterPro; IPR035892; C2_domain_sf.
DR   InterPro; IPR037723; C2D_Ferlin.
DR   InterPro; IPR037721; Ferlin.
DR   InterPro; IPR010482; Peroxin.
DR   InterPro; IPR006614; Peroxin/Ferlin.
DR   PANTHER; PTHR12546; FER-1-LIKE; 1.
DR   PANTHER; PTHR12546:SF33; SPERM VESICLE FUSION PROTEIN FER-1; 1.
DR   Pfam; PF00168; C2; 2.
DR   Pfam; PF06398; Pex24p; 1.
DR   SMART; SM00239; C2; 1.
DR   SMART; SM00694; DysFC; 2.
DR   SMART; SM00693; DysFN; 1.
DR   SUPFAM; SSF49562; C2 domain (Calcium/lipid-binding domain, CaLB); 1.
DR   PROSITE; PS50004; C2; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT   DOMAIN          250..386
FT                   /note="C2"
FT                   /evidence="ECO:0000259|PROSITE:PS50004"
FT   REGION          229..254
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        229..250
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ETE64296.1"
SQ   SEQUENCE   712 AA;  82912 MW;  0E2989ADC82A0D07 CRC64;
     MDLMPHPNFS DVTGQVSLPK DTFQLPMGWQ WDKTNYSEVM QEVYENQSRQ PSRRWKPARV
     PYSNASGVPA PRKEDILCPP GWIFIEEWKV ELNRAVDDAG KETGYLFSSL GWEYGIAIPP
     AEFPHSWNAA EKTYHTHRRR RWLRKRFRNL GRETQQNQMA AFLQLHLDIK AKEYVWEYAP
     LYGWRFHLQR QPDDVFRRRC WRRKLAPVAP SVVAPIFYLE GSLGVEVGDR QKRKKPEAGR
     KDEKEEVEQE PPASQGLLKK NTPLLYCVFK SPLYFQLRCY MYQARDLLRS IVKGTADPVA
     HVSFLHLSHC THIISGTLHP CWDETLLFED ILIYGDPQGT AQDPPIVAVE IFDYDSNARS
     NDFMGRCICI PMVCLDLNVR RIPRLQKQPI TRNEEESGYL MAAFELLLDR KYLPVDEDYS
     PPIELKVIDH RDFGYKPVVG QATVRSLSQY YCNPLEESKV HNLPPRGMLY KPGSPFVVMG
     AERSILGHST MVLILFLIWF NVYVRPLEET EEEEEEEEEE EIDWWSKYYA TMGDLSKSGH
     YLEKGYDSIK IYNCELEEVP EFHGLQDFCQ TFQLYRGKVQ DDDPVVGGEF KCDPYIKIKL
     GKERMADREE YIPNTLDPVF GRSGKLQMWV DLFPLYLGDP GPPFDITPRK PRKYELRCII
     WNTKDVDLED TNIFGDKMSD IYVKGYEISN LGGDPNQVHF DKESISSVLK NM
//