ID V8NR41_OPHHA Unreviewed; 278 AA.
AC V8NR41;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 30.
DE SubName: Full=Cyclic AMP-dependent transcription factor ATF-5 {ECO:0000313|EMBL:ETE64520.1};
GN Name=Atf5 {ECO:0000313|EMBL:ETE64520.1};
GN ORFNames=L345_09703 {ECO:0000313|EMBL:ETE64520.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE64520.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE64520.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE64520.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the bZIP family.
CC {ECO:0000256|ARBA:ARBA00007163}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE64520.1}.
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DR EMBL; AZIM01002211; ETE64520.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NR41; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0042981; P:regulation of apoptotic process; IEA:UniProt.
DR CDD; cd14692; bZIP_ATF4; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR PANTHER; PTHR13044; ACTIVATING TRANSCRIPTION FACTOR ATF 4/5; 1.
DR PANTHER; PTHR13044:SF3; CYCLIC AMP-DEPENDENT TRANSCRIPTION FACTOR ATF-5; 1.
DR Pfam; PF00170; bZIP_1; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 203..266
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT COILED 221..262
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 278 AA; 30964 MW; EBDB4886E6284D5A CRC64;
MTNTMSLLAA VTLDLDLTMI PASTMSYRPE LLKHRLPHAG HSELLPGPVD QGFALGMERP
VLTGDGFSDW MTERTDLATL LSVSGESSPL SLPSPPAPDL EAMASLLKKE LEQMEDYFLE
ETLSPDQVAP STPPSDGNFH FPFGDGFHSL DHHHSTPAPL QTLDSSCLEL LELYGGEMPA
ELPLQGNEIC ASVQQSLVLT PKGDRRQKKR DQNKTAALRY RQRKRAEHEA LGDECQALEA
HNRELREKAE SIEREIQYVK DLLIEVYKAR SQRLRTAP
//
