ID V8NTI8_OPHHA Unreviewed; 268 AA.
AC V8NTI8;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Type I cytokine receptor cytokine-binding domain-containing protein {ECO:0000259|Pfam:PF09240};
DE Flags: Fragment;
GN ORFNames=L345_09368 {ECO:0000313|EMBL:ETE64862.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE64862.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE64862.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE64862.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004479}; Single-
CC pass type I membrane protein {ECO:0000256|ARBA:ARBA00004479}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE64862.1}.
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DR EMBL; AZIM01002077; ETE64862.1; -; Genomic_DNA.
DR AlphaFoldDB; V8NTI8; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0004896; F:cytokine receptor activity; IEA:InterPro.
DR Gene3D; 2.60.40.10; Immunoglobulins; 2.
DR InterPro; IPR036116; FN3_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR003532; Short_hematopoietin_rcpt_2_CS.
DR InterPro; IPR015321; TypeI_recpt_CBD.
DR PANTHER; PTHR23036; CYTOKINE RECEPTOR; 1.
DR PANTHER; PTHR23036:SF89; INTERLEUKIN-13 RECEPTOR SUBUNIT ALPHA-1; 1.
DR Pfam; PF09240; IL6Ra-bind; 1.
DR SUPFAM; SSF49265; Fibronectin type III; 1.
DR PROSITE; PS01356; HEMATOPO_REC_S_F2; 1.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 40..129
FT /note="Type I cytokine receptor cytokine-binding"
FT /evidence="ECO:0000259|Pfam:PF09240"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE64862.1"
SQ SEQUENCE 268 AA; 30808 MW; 5BA232504B9107DD CRC64;
MVDIKATNLG SMLLKKELID TCNIKSPEIK NMNGTSVENV DCIVRSYTFK NPTMNCTWKA
GKTAPPDTQY FMYLAYHKAT DNECPHYISN TFGRHVGCYF PEVIANQYRV VITINGSSID
PPIQTYVDDF RLYDKEQFRP PQNITVDYSS PLYYNVQWEP PPNSRKLGSD CFEFQIKDER
RNTIINWVTP EPIADESITV VEEMTAISPK DLKLLADLQA KADQLPWTLN CSYYNQHQRQ
DKSNELDNSK ISSSVDDYAL DRDIEALI
//
