ID V8NTQ1_OPHHA Unreviewed; 2100 AA.
AC V8NTQ1;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=Golgin subfamily A member 3 {ECO:0000313|EMBL:ETE64917.1};
DE Flags: Fragment;
GN Name=Golga3 {ECO:0000313|EMBL:ETE64917.1};
GN ORFNames=L345_09313 {ECO:0000313|EMBL:ETE64917.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE64917.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE64917.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE64917.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE64917.1}.
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DR EMBL; AZIM01002059; ETE64917.1; -; Genomic_DNA.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0005543; F:phospholipid binding; IEA:InterPro.
DR CDD; cd00176; SPEC; 2.
DR Gene3D; 1.20.58.60; -; 3.
DR Gene3D; 2.30.29.30; Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB); 1.
DR InterPro; IPR011993; PH-like_dom_sf.
DR InterPro; IPR001605; PH_dom-spectrin-type.
DR InterPro; IPR018159; Spectrin/alpha-actinin.
DR InterPro; IPR002017; Spectrin_repeat.
DR PANTHER; PTHR11915:SF445; PH DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR11915; SPECTRIN/FILAMIN RELATED CYTOSKELETAL PROTEIN; 1.
DR Pfam; PF00435; Spectrin; 2.
DR PRINTS; PR00683; SPECTRINPH.
DR SMART; SM00150; SPEC; 3.
DR SUPFAM; SSF50729; PH domain-like; 1.
DR SUPFAM; SSF46966; Spectrin repeat; 4.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..22
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 23..2100
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004771149"
FT REGION 603..629
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1704..1727
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1807..1829
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 2050..2075
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 327..354
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 399..462
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 753..780
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 825..852
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 903..937
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 603..617
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1704..1723
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE64917.1"
SQ SEQUENCE 2100 AA; 236950 MW; BCD54490C11352BA CRC64;
MPAPLLALLL LRTLLTRLLL LARKXXLTRI LLLARKRLLP LLRRLRARLT SQQSREAILT
CLLCLLNLRK KGPCKACARE TMSGSTARKI QPFTISTKLS LPKCSLEFPR DSCTDIPLDA
LNNHDLHQNL NECVSLYLAQ TSLEPAGERF KSASPIEEEV TNDDCINSNS LSRSIKKITL
SNWHGKGGLG EEGIFRGPSH TSAEKNYNNN NCKAGKAQFK VFLRKEVEPK EEKQNARSPE
AGDNSLVSRV APFVTASSAA ASPWKESTKS TKPGKVVELK PCIESSSPGV ADLSRWSLLL
AQFNCDMVQA EKWMRGKLHD LKDGCRFQEW ERIAQILQRE MKDFENTIIK LNQMGEQLMI
QPKSSTEIER RLQTLQEQWQ LLKHMATNQT KTVVGFKSLQ EFNQKAEQLE TWIRQKEEKP
LLAILLQEKA DKVQITRQIL DLKQEQLQFQ AVHEELNSLA QKLEKQGKSE SRSIMARRKY
LNKMWLQLQR TLKEHHETLQ QALEAASFLQ QADVLLSVIH AKLRHLYGER KQNESESSPD
MDIRDIASQV MMLDVTMSQL ISLHPSLAAQ VSLKHQDIKE SWARLQQLLR SDNPPQLALT
KELIDSNPNQ VLTTTTKSPE EDPEEDPEEK LVWEEIQQLP STDHRWSPEM EDALEELGEL
WAELKKRHQE NGKALQEIDT ALQLVGELEA AECWLETVAG LLSEPRATKN LDDLQSDLQK
VGTLKNKAGA WAAKIHTLQE EMQMVASSEH TAAAMIQRKM KRVKEKLACV QEALQRQASD
LHDSLILMEF LQTGAPNQFS SPESLHLVLA QSAQQGNSKD MSRPLKELQE AVEMLNNVVK
EREQALKAAT QTKSLECFPQ VMKDKEEIGI ETIRERSETL AQDLIQVERS FTTVKSEMDL
LDVQGIQKRQ EEIESDMSQL EGNIEELERA VTHLVQVSDD SKWILEILEA WKDLQKLVLE
NSVHGQQTVR LRQFFKGYLA IISWTEDTRA QIFSENLNAQ GLSEAPWENL KNSMEAKFKE
FEELAASGWE LVTEDHYLSK TRMEELQNML GWMMVRYQAQ CSPKDLGNKN DERETQDSTL
NMPQNLQIEL NPRADVTETD GILNSKVLMK CSAGNYHKQQ NEPVSTAFAL NVPPGYKQGL
EESGNDLPFE VDVPKGILVL EPSETPVLLV PQAPPGSLGS MVSLILNIAK EGEKKATGSQ
AASSPTVEQE TSHKVSTYLH VKEKDGCGNQ DPDFGNSAFI SESVKQVPPR VPSSPFSRVE
WSKAASHTFP KISSSCSLKS PKGKTKEMAG DIQRLTLQRI MGTKANYLQE VKYSMSNTWP
PRCTQRVQVL QALSLPQREL MDHVKNPLDW AIDAECDLPR ETSGKCIFLK QNTSLHSHHV
STEKMNTCQH LSLGSVLSLE LPKDLSALRN VHDIVKVARD EVAERKGANQ VNQVAQRSTE
EAKTHETSIS LEKETIRGQR VMHSKPVRAE DVSHKVPKSK KGTWFEEVNL NPSYGRQKTY
SVACSEEVRL HPKSQNNSSD ECFDFKQNKP PHTSVFHEQI DLEWDKLAAS LDRMGISKEK
QVKDVDDKRA KVQEALRLKL KPSSAESTRN PDLVSHLTGM KDPLVNEISE KENTQCSEES
ISRHPSTFLH LGHKSPTKPS KLDCELGYEE NTQSNPKLCP FNLTPRAEVP KGTKLQGMAA
EVRHPAHEMF EEEEEELQAI WNNMEKHKKG SDVPDDPGRK MDKEQSLGSS SGKLLLTSAD
NWLIAKFKLP TSVEMLQNSE GGRRASLGVD KRKNRPNQCG KANISSCQEL NKEAASSPGE
LSLQKIYPAD QQKFQEESKG VSKTHPSKLE LQMMEGLLER KNLLQAGGRK ANSRSWNTFH
TVLMRQTLCF YQDKKDTLKY LLRAPTEPLM KEWVTKLQQN SGLPEVYFFP SSSQPAQGMT
SAVSAIPGQG VSHFQSFQKK LPTKSQEIRF LPKSSVKLQL PYSAHSEPLE TTGNGLRAAP
IYTTEQNLKQ CSPLESASSQ EPQFYQEDDW GLVTSKRRSY SFTSATYQKI TPLSKSKEPN
NYSVTLYIGE QAPTTPPRPR CHSFIASPGG AREMVGEHNQ SASPIQKNKS VFRKFFGKKD
//
