ID V8P1W0_OPHHA Unreviewed; 489 AA.
AC V8P1W0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 22-FEB-2023, entry version 18.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 8 {ECO:0000256|ARBA:ARBA00020983};
DE AltName: Full=Component of oligomeric Golgi complex 8 {ECO:0000256|ARBA:ARBA00031347};
GN Name=COG8 {ECO:0000313|EMBL:ETE68181.1};
GN ORFNames=L345_06038 {ECO:0000313|EMBL:ETE68181.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE68181.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE68181.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE68181.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000256|ARBA:ARBA00004395}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004395}. Membrane
CC {ECO:0000256|ARBA:ARBA00004170}; Peripheral membrane protein
CC {ECO:0000256|ARBA:ARBA00004170}.
CC -!- SIMILARITY: Belongs to the COG8 family.
CC {ECO:0000256|ARBA:ARBA00006419}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE68181.1}.
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DR EMBL; AZIM01001080; ETE68181.1; -; Genomic_DNA.
DR AlphaFoldDB; V8P1W0; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR007255; COG8.
DR InterPro; IPR016632; COG8_Metazoal_Plant.
DR InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR PANTHER; PTHR21311; CONSERVED OLIGOMERIC GOLGI COMPLEX COMPONENT 8; 1.
DR PANTHER; PTHR21311:SF0; CONSERVED OLIGOMERIC GOLGI COMPLEX SUBUNIT 8; 1.
DR Pfam; PF04124; Dor1; 1.
DR PIRSF; PIRSF015415; COG8; 1.
DR SUPFAM; SSF74788; Cullin repeat-like; 1.
PE 3: Inferred from homology;
KW Golgi apparatus {ECO:0000256|ARBA:ARBA00023034};
KW Membrane {ECO:0000256|ARBA:ARBA00023136};
KW Protein transport {ECO:0000256|ARBA:ARBA00022927};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Transport {ECO:0000256|ARBA:ARBA00022448}.
FT REGION 451..489
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 489 AA; 54190 MW; D9319BBD02259FEA CRC64;
MRHAEQIAQN RRMNNGTLNR HTEILEVLEI PQLMDTCVRN SYYEEALELV SYVRRLEKKH
AGIPVVQGIV AEVRQSTQLM LTQLIQQLRT NIQLPACLRV IGYLRCMDVF TEAELRITFL
QARDFWLRSI LAAVPDDDPY VHITKTIEAC RVHLFDIVTQ YRAIFADEEP LVLPLGKDTF
NESAIFHGWV LQKVSQFLLV LERDLQRGVG NRLDSLLGQC MYFGLSFSRV GADFRGQLVP
IFQHVVLLAF KKAMQEATDQ FQEEMNSYTL ISAPALLGSA ISVPMPSAQP GTLQPPLVLL
DFPPLAHLIN NILMAFNDLR LCCPVALAPV VAALLENVLS QGVKIILAFH RAEAAAFSSQ
EQELFVQFCT AFLEDLVPYL NRCLQLLFPL AQIAQILGVP AARVHKYGGL ACVDEEAIQE
LLGSVLPKKE TTLPLTEKGM ALQLPLDLGL SGSEQEGADP SRAVSVSSAA KKSPLPEDAR
PPSGVSATA
//
