ID   V8P293_OPHHA            Unreviewed;       915 AA.
AC   V8P293;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 24.
DE   SubName: Full=Ribonucleases P/MRP protein subunit POP1 {ECO:0000313|EMBL:ETE68624.1};
DE   Flags: Fragment;
GN   Name=POP1 {ECO:0000313|EMBL:ETE68624.1};
GN   ORFNames=L345_05571 {ECO:0000313|EMBL:ETE68624.1};
OS   Ophiophagus hannah (King cobra) (Naja hannah).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX   NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE68624.1, ECO:0000313|Proteomes:UP000018936};
RN   [1] {ECO:0000313|EMBL:ETE68624.1, ECO:0000313|Proteomes:UP000018936}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Blood {ECO:0000313|EMBL:ETE68624.1};
RX   PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA   Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA   McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA   Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA   de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA   Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA   Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA   Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT   "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT   snake venom system.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETE68624.1}.
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DR   EMBL; AZIM01000972; ETE68624.1; -; Genomic_DNA.
DR   AlphaFoldDB; V8P293; -.
DR   Proteomes; UP000018936; Unassembled WGS sequence.
DR   GO; GO:0005655; C:nucleolar ribonuclease P complex; IEA:InterPro.
DR   GO; GO:0000172; C:ribonuclease MRP complex; IEA:InterPro.
DR   GO; GO:0001682; P:tRNA 5'-leader removal; IEA:InterPro.
DR   InterPro; IPR039182; Pop1.
DR   InterPro; IPR009723; Pop1_N.
DR   InterPro; IPR012590; POPLD_dom.
DR   PANTHER; PTHR22731; RIBONUCLEASES P/MRP PROTEIN SUBUNIT POP1; 1.
DR   PANTHER; PTHR22731:SF3; RIBONUCLEASES P_MRP PROTEIN SUBUNIT POP1; 1.
DR   Pfam; PF06978; POP1_N; 2.
DR   Pfam; PF08170; POPLD; 1.
PE   4: Predicted;
KW   Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW   tRNA processing {ECO:0000256|ARBA:ARBA00022694}.
FT   DOMAIN          52..100
FT                   /note="Pop1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06978"
FT   DOMAIN          117..185
FT                   /note="Pop1 N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF06978"
FT   DOMAIN          527..618
FT                   /note="POPLD"
FT                   /evidence="ECO:0000259|Pfam:PF08170"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         915
FT                   /evidence="ECO:0000313|EMBL:ETE68624.1"
SQ   SEQUENCE   915 AA;  104476 MW;  53219966395E8C5E CRC64;
     MSNAKQKRRG KKMKNQPASV TCPFDAGPSH SEAYFWNGGE RTPQRKKQVS PFVQARAAEI
     KAMLKAVKQK SSNTLVFQSL PRHMRRRAMS HNIKRLPRRL PLSKSKCRKA RRRHINLVVE
     FNRRQRKNIW LETHIWHAKR FHMVKKWGYC LGDKPTMKSY RACYRAMTQH CLLQDLSYYC
     CLELIGKEET LVTALARMCN VDTGSLVLYQ TDRYPQDTLG PVTFLWKPRH GSGETSENRQ
     LWIWTHPAFK QGILAELKSV FQCSEPVETC KPELVVTLSQ EEDKMNIPEH VGHKRKRKDK
     AGETVVPVKK IIGDGTRDPN QPYCWSSQTT GITISDLTME ILRYRLIGPL SHCVLTEALK
     VAFVHMDLDP TDSEINSWWV ENCKNPDWVS LHHCQESVFE TMQGLASSDI PSGTVLGLTV
     GDPRVNLPKK RSKAMPNPAK YQEDKVKQLI LEGVSEECAQ SFLWDSNIRN SVTDHKMSEQ
     DLNHLRSKLL VPGSHLDLGL RESKIPILLV QQPGKLLGDD RLGWGSGWDI YLPKGWGMAF
     WLPFIYQGAR VGGLQEALKH SLYKGTPHVP HDYPDCPAGS QVAKELEENL LEKFKRRPPA
     KRANYIKHGT LAPFLCPWDK LTQDWETRYK VHRKSTQIPA LDREDCVPEE HVGGPSSTTS
     MVDAPTSKAD QIDTCCQIME MENEEKAIDP CKTDEVISGQ VFCILRTRKL LRQISFWCHP
     TSGKRRYRQH RASKMNEKEL AEDTQMSINL HYPRALVWVS LSLLRKGNPE LHTMICIPEK
     DDLLQLNNDQ HFCGPQEPKH KDKFKNKLWK RKGRTKKAKD GKVIEKSALK QEDLVLGLWP
     HPLPDVVSHC SRVLLGFVTQ GDFSLASGCG EALGFVSLTG LLQMLIDQPA DKKGLVLLRN
     PASLQYRFAR LSVEV
//