ID V8P586_OPHHA Unreviewed; 766 AA.
AC V8P586;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 34.
DE SubName: Full=Leucine-zipper-like transcriptional regulator 1 {ECO:0000313|EMBL:ETE69141.1};
DE Flags: Fragment;
GN Name=LZTR1 {ECO:0000313|EMBL:ETE69141.1};
GN ORFNames=L345_05056 {ECO:0000313|EMBL:ETE69141.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE69141.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE69141.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE69141.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE69141.1}.
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DR EMBL; AZIM01000836; ETE69141.1; -; Genomic_DNA.
DR AlphaFoldDB; V8P586; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR CDD; cd18506; BACK2_LZTR1; 1.
DR CDD; cd18308; BTB1_POZ_LZTR1; 1.
DR CDD; cd18309; BTB2_POZ_LZTR1; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR46376; LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1; 1.
DR PANTHER; PTHR46376:SF1; LEUCINE-ZIPPER-LIKE TRANSCRIPTIONAL REGULATOR 1; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF13415; Kelch_3; 2.
DR Pfam; PF13418; Kelch_4; 1.
DR Pfam; PF13964; Kelch_6; 1.
DR SMART; SM00225; BTB; 2.
DR SMART; SM00612; Kelch; 4.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 2.
DR PROSITE; PS50097; BTB; 2.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 380..480
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT DOMAIN 593..662
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE69141.1"
SQ SEQUENCE 766 AA; 87774 MW; 3EAB866064B56BF0 CRC64;
MAAAANSGGR SKVAPSVDFD HSCSDSVEYL TLNFGPFETV HRWRRLPPCD EFVGARRSKH
TVVAYRDAIY VFGGDNGKTM LNDLLRFDVK DCSWCRAFTT GTPPAPRYHH SAVVYGSSMF
VFGGYTGDIY SNSNLKNKND LFEYKLATGQ WTEWKIEGRL PVARSAHGAT VYSDKLWIFA
GYDGNARLND MWTINLQDRD LTCWEEIKQT GEIPPSCCNF PVAVCKERMF VFSGQSGAKI
TNNLFQFEFK EKIWTRIPTE HLLRGSPPPP QRRYGHTMVA FDRHLYVFGG AADNTLPNEL
HCYDVDSQTW EVIQPSPDSE LPTGRLFHAA AVICDAMYIF GGTVDNNIRS GEMYRFQFSC
YPKCTLHDDY GRLWENRQFS DLEFVLGEKE ERVRGHTAIV TARCKWLRKK ITQAKERLKQ
KSKQEVNEEG QEVPQKEMAG NNVKIARLQP LLEVTIREAE AQPFEVLMQF LYTDKIKYPR
KGHVQDVLLI MDVYKLALNF KLSRLEQLCV QYIEASVDLQ NEHCLNFVVK ESHFNQVIMM
KEFEHLSSSL IVEIVRRKQQ PPLRTHSDQP LDIGTSLIQD MKAYLEGAGL EFCDIILLLD
GHPRPAHKAI LAARSSYFEA MFRSFMPEDG QVNISIGEMV PSKQAFESML RYIYYGEVNM
PPEDSLYLFA APYYYGFYNN RLQAYCKQNL EMNVTVENVL QILEAADRTQ ALDMKRHCLY
IIVHQFTKVS KLPNLRSLSQ PLLLDIIESL ANHISDKQCA ELGADI
//
