ID V8P5M0_OPHHA Unreviewed; 442 AA.
AC V8P5M0;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 31.
DE SubName: Full=General transcription factor IIE subunit 1 {ECO:0000313|EMBL:ETE69276.1};
DE Flags: Fragment;
GN Name=GTF2E1 {ECO:0000313|EMBL:ETE69276.1};
GN ORFNames=L345_04910 {ECO:0000313|EMBL:ETE69276.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE69276.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE69276.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE69276.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SIMILARITY: Belongs to the TFIIE alpha subunit family.
CC {ECO:0000256|ARBA:ARBA00008947}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE69276.1}.
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DR EMBL; AZIM01000798; ETE69276.1; -; Genomic_DNA.
DR AlphaFoldDB; V8P5M0; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR Gene3D; 6.10.140.1250; -; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 1.
DR InterPro; IPR039997; TFE.
DR InterPro; IPR017919; TFIIE/TFIIEa_HTH.
DR InterPro; IPR002853; TFIIE_asu.
DR InterPro; IPR021600; TFIIE_asu_C.
DR InterPro; IPR024550; TFIIEa/SarR/Rpc3_HTH_dom.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13097:SF8; GENERAL TRANSCRIPTION FACTOR IIE SUBUNIT 1; 1.
DR PANTHER; PTHR13097; TRANSCRIPTION INITIATION FACTOR IIE, ALPHA SUBUNIT; 1.
DR Pfam; PF11521; TFIIE-A_C; 1.
DR Pfam; PF02002; TFIIE_alpha; 1.
DR SMART; SM00531; TFIIE; 1.
DR SUPFAM; SSF57783; Zinc beta-ribbon; 1.
DR PROSITE; PS51344; HTH_TFE_IIE; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT DOMAIN 14..104
FT /note="HTH TFE/IIEalpha-type"
FT /evidence="ECO:0000259|PROSITE:PS51344"
FT REGION 346..366
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE69276.1"
SQ SEQUENCE 442 AA; 50112 MW; 1BA2181D7C703FD2 CRC64;
MTDPDILTEV PASLKRLAKY VVRGFYGTEH ALALDILIRN PCVKEEDMLE LLKFDRKQLR
AILNTLKGDK FIKCRMRVET APDGKTTRHN FYFINYRLLV NVVKYKLDHM RRRIETDERD
STNRASFRCP ICSSTFTDLE ANQLFEPNTG IFRCTFCETE VEEDESAMPK KDARTLVARF
NEQIEPIYAL LRETEDVNLA YELLEPEPME ILALKQSKER AVGALGNSSL PSGQHREAWT
TKGPSYGDMY TQNVIINMED QEDTHQPTNE GKLPRERPVW LRESTVQGAY DPNEVTEGGQ
DINMLHEDEE GQAALDNNEE VMRALLIHEK KTSSVSTAAM GGIAPLSATN ASDSESETSE
SDEDSLPCAA AATAPTMLYG LTDDNDEDEF EVVTEDPIVM VAGHPFSYSQ VNQRPELVSQ
MTVEEKEQYI AMGQRMFEDM FD
//
