ID V8P6W9_OPHHA Unreviewed; 645 AA.
AC V8P6W9;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 22-FEB-2023, entry version 30.
DE SubName: Full=Protein Jade-3 {ECO:0000313|EMBL:ETE70070.1};
DE Flags: Fragment;
GN Name=PHF16 {ECO:0000313|EMBL:ETE70070.1};
GN ORFNames=L345_04118 {ECO:0000313|EMBL:ETE70070.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE70070.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE70070.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE70070.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE70070.1}.
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DR EMBL; AZIM01000622; ETE70070.1; -; Genomic_DNA.
DR AlphaFoldDB; V8P6W9; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd15681; PHD_JADE3; 1.
DR Gene3D; 3.30.40.10; Zinc/RING finger domain, C3HC4 (zinc finger); 3.
DR InterPro; IPR019542; Enhancer_polycomb-like_N.
DR InterPro; IPR034732; EPHD.
DR InterPro; IPR039550; JADE3_PHD.
DR InterPro; IPR019786; Zinc_finger_PHD-type_CS.
DR InterPro; IPR011011; Znf_FYVE_PHD.
DR InterPro; IPR001965; Znf_PHD.
DR InterPro; IPR019787; Znf_PHD-finger.
DR InterPro; IPR013083; Znf_RING/FYVE/PHD.
DR PANTHER; PTHR13793; PHD FINGER PROTEINS; 1.
DR PANTHER; PTHR13793:SF27; PROTEIN JADE-3; 1.
DR Pfam; PF10513; EPL1; 1.
DR Pfam; PF13831; PHD_2; 1.
DR Pfam; PF13832; zf-HC5HC2H_2; 1.
DR SMART; SM00249; PHD; 2.
DR SUPFAM; SSF57903; FYVE/PHD zinc finger; 1.
DR PROSITE; PS51805; EPHD; 1.
DR PROSITE; PS01359; ZF_PHD_1; 1.
DR PROSITE; PS50016; ZF_PHD_2; 1.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}; Signal {ECO:0000256|SAM:SignalP};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00146}.
FT SIGNAL 1..23
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 24..645
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5004771257"
FT DOMAIN 204..254
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS50016"
FT DOMAIN 256..289
FT /note="PHD-type"
FT /evidence="ECO:0000259|PROSITE:PS51805"
FT REGION 598..645
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 598..632
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE70070.1"
SQ SEQUENCE 645 AA; 74505 MW; B0D2E071762132CA CRC64;
QISIFFLLIL FPFLAVHIGP STSFSFCSKY RSKSKTPTNE QKKPAEVFRK DLISAMKLPD
SHHINPDEYY LFADTWKQEW EKGVQVPASP ETIPQPSLRI VAEKVKQVLY TRPRKYIRCS
NQESAEPGYI NILELAESMC RYDLDDMDIF WLQEVNEELA EMGYGQLDEN TMEKMLEVLE
RHCHENMNHA IETEEGLGIE YDEDVICDVC RSPDSEDGND MVFCDKCNIC VHQACYGILK
VPEGSWLCRT CVLGIHPQCL LCPKRGGAMK ATRTGTKWAH VSCALWIPEC SVKSCITAFH
VTCAFEHSLE MKTILDDGDE VKFKSYCLKH SKTKQNLIPD TENLKSTVDQ KQTESEKTSL
RAQKLQELEE EFYSLVRIDD VAAELGLPKL TVDLTFNYWK LKRKSNFNKP LFPPKEDEEN
GLVQPKEDSI HTRMRMFMHL RQDLERVRNL CYMVSRREKI KLSHSKAHEQ VFNLQVQLIN
QEIAAEKSNG LMSRIGDITQ RDSSSQTTYE QQSVLSAHQA SQSTFRKSTM EHFSRSFKEA
TNSLVRTTED LRCEKPSRRL SVRERPWGKQ TFEYQMGISN APYQDNDGYC PDLELSDSEA
ESEKNKGQIR LRKSSSGRES PNKDFSRDCQ HRKKRNLISH SSVQR
//
