ID   V8P941_OPHHA            Unreviewed;       526 AA.
AC   V8P941;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 19.
DE   SubName: Full=Peptidase M20 domain-containing protein 2 {ECO:0000313|EMBL:ETE70518.1};
DE   Flags: Fragment;
GN   Name=pm20d2 {ECO:0000313|EMBL:ETE70518.1};
GN   ORFNames=L345_03670 {ECO:0000313|EMBL:ETE70518.1};
OS   Ophiophagus hannah (King cobra) (Naja hannah).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC   Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX   NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE70518.1, ECO:0000313|Proteomes:UP000018936};
RN   [1] {ECO:0000313|EMBL:ETE70518.1, ECO:0000313|Proteomes:UP000018936}
RP   NUCLEOTIDE SEQUENCE.
RC   TISSUE=Blood {ECO:0000313|EMBL:ETE70518.1};
RX   PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA   Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA   McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA   Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA   de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA   Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA   Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA   Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT   "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT   snake venom system.";
RL   Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETE70518.1}.
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DR   EMBL; AZIM01000537; ETE70518.1; -; Genomic_DNA.
DR   AlphaFoldDB; V8P941; -.
DR   MEROPS; M20.021; -.
DR   Proteomes; UP000018936; Unassembled WGS sequence.
DR   GO; GO:0016787; F:hydrolase activity; IEA:UniProt.
DR   CDD; cd05672; M20_ACY1L2-like; 1.
DR   Gene3D; 3.30.70.360; -; 1.
DR   Gene3D; 3.40.630.10; Zn peptidases; 1.
DR   InterPro; IPR036264; Bact_exopeptidase_dim_dom.
DR   InterPro; IPR011650; Peptidase_M20_dimer.
DR   PANTHER; PTHR30575; PEPTIDASE M20; 1.
DR   PANTHER; PTHR30575:SF0; XAA-ARG DIPEPTIDASE; 1.
DR   Pfam; PF07687; M20_dimer; 1.
DR   SUPFAM; SSF55031; Bacterial exopeptidase dimerisation domain; 1.
DR   SUPFAM; SSF53187; Zn-dependent exopeptidases; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT   DOMAIN          221..314
FT                   /note="Peptidase M20 dimerisation"
FT                   /evidence="ECO:0000259|Pfam:PF07687"
FT   NON_TER         1
FT                   /evidence="ECO:0000313|EMBL:ETE70518.1"
SQ   SEQUENCE   526 AA;  57949 MW;  C2978C2DBE564B84 CRC64;
     MRPNEAGEAS SASEVRLDEW KRWAAECIDE SSERLGELSR EIWSHPELAF EEHQAHAALT
     SFFAGLPVSS SSAAWSVQRS YKLETAFRAD WKWDGAPCSP AETNQATPPS PPPLRLGFLC
     EYDALPAIGH ACGHNLIAEV GAAAALGLKG ALESLRQNPA GLPRQAPAVK VTVLGTPAEE
     DGGGKIDLIK AGAFDNLDVV FMAHPSQEDA AYLPDIAEHD VTVKYYGKTS HAAAYPWEGL
     NALDAAVLAY NNLSLLRQQM KPTWRVHGII KNGGVKPNII PSYTELEFYL RAPSLRELST
     LKEKAENCFK AAALATGCEV EIHDNEADFY NRIYMGAEYF YLLYPLIILL FANPYNNISP
     YRLFGIFQNL TMFWLSLGST DFGNVSYVIP GIHSYFYIGS DALNHTEQYT MAAGSEEAQF
     YALRAAKALA MTALDVIFKP DVLEKVREDF RLTKLKEEGH LNVPGNTKGS DNGIEAETLS
     LFRNILYEHQ TVPLLQKIII SPLKKKCGSG GIFLSEKLQN PVVTIL
//