ID V8PDJ2_OPHHA Unreviewed; 450 AA.
AC V8PDJ2;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 22-FEB-2023, entry version 27.
DE SubName: Full=Myotubularin-related protein 11 {ECO:0000313|EMBL:ETE72068.1};
DE Flags: Fragment;
GN Name=Mtmr11 {ECO:0000313|EMBL:ETE72068.1};
GN ORFNames=L345_02118 {ECO:0000313|EMBL:ETE72068.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE72068.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE72068.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE72068.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- SIMILARITY: Belongs to the protein-tyrosine phosphatase family. Non-
CC receptor class myotubularin subfamily. {ECO:0000256|ARBA:ARBA00007471}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE72068.1}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AZIM01000274; ETE72068.1; -; Genomic_DNA.
DR AlphaFoldDB; V8PDJ2; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR InterPro; IPR022587; MTMR12-like_C.
DR InterPro; IPR010569; Myotubularin-like_Pase_dom.
DR InterPro; IPR030564; Myotubularin_fam.
DR InterPro; IPR029021; Prot-tyrosine_phosphatase-like.
DR PANTHER; PTHR10807; MYOTUBULARIN-RELATED; 1.
DR PANTHER; PTHR10807:SF51; MYOTUBULARIN-RELATED PROTEIN 11; 1.
DR Pfam; PF12578; 3-PAP; 1.
DR Pfam; PF06602; Myotub-related; 2.
DR SUPFAM; SSF52799; (Phosphotyrosine protein) phosphatases II; 1.
DR PROSITE; PS51339; PPASE_MYOTUBULARIN; 1.
PE 3: Inferred from homology;
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 14..443
FT /note="Myotubularin phosphatase"
FT /evidence="ECO:0000259|PROSITE:PS51339"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE72068.1"
FT NON_TER 450
FT /evidence="ECO:0000313|EMBL:ETE72068.1"
SQ SEQUENCE 450 AA; 52555 MW; 00A446470CDAC0D4 CRC64;
QDIQLQEGFS VVLFETLCDW EKELKRLGAA GWRVSPVNER FDMSTSLPKY LWVPNRFLDN
ELKRAFVHFN ERRIPRLCWH HTNGSDLLRA ANFHTNSDPE KEDIRAIETL LFAGHSQCVI
VEATADLPSL PEIHQSYSKL WNLSLCLTDT SVAPSDEKWL SKSDDRDLNC LLASLVQILS
DPYNRTIHGF QSLIQKEWVA AGHPFLQRLN VLQKNDQDES PVFFLFLDSI WQLLQQFPQS
FEFTEAYLMA IYDSCFIPFS SSFLFNCQWE RSRKNQNHFL NQIYTPINGW QENLCSEILQ
KGGYPIKNVG HTNLSTVWNW LLRSNTWQIA QFRNPWYNEN KLSNEGTLNK NFLFKNGDKM
ENSSSEKRTL YIFSKGSLSL QSHIFPWKNG ILSKKSFHRV QALETSREER SWKAKSNGSF
IYHDLLLLPS HTGTSIRLWK RCYLRGNPEV
//
