ID V8PGW6_OPHHA Unreviewed; 589 AA.
AC V8PGW6;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 35.
DE SubName: Full=Ectoderm-neural cortex protein 2 {ECO:0000313|EMBL:ETE73575.1};
DE Flags: Fragment;
GN Name=KLHL25 {ECO:0000313|EMBL:ETE73575.1};
GN ORFNames=L345_00590 {ECO:0000313|EMBL:ETE73575.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE73575.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE73575.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE73575.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE73575.1}.
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DR EMBL; AZIM01000072; ETE73575.1; -; Genomic_DNA.
DR AlphaFoldDB; V8PGW6; -.
DR UniPathway; UPA00143; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR GO; GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway.
DR Gene3D; 1.25.40.420; -; 1.
DR Gene3D; 2.120.10.80; Kelch-type beta propeller; 2.
DR InterPro; IPR011705; BACK.
DR InterPro; IPR017096; BTB-kelch_protein.
DR InterPro; IPR000210; BTB/POZ_dom.
DR InterPro; IPR015915; Kelch-typ_b-propeller.
DR InterPro; IPR006652; Kelch_1.
DR InterPro; IPR011333; SKP1/BTB/POZ_sf.
DR PANTHER; PTHR24412; KELCH PROTEIN; 1.
DR PANTHER; PTHR24412:SF488; KELCH-LIKE PROTEIN 20; 1.
DR Pfam; PF07707; BACK; 1.
DR Pfam; PF00651; BTB; 1.
DR Pfam; PF01344; Kelch_1; 5.
DR PIRSF; PIRSF037037; Kelch-like_protein_gigaxonin; 1.
DR SMART; SM00875; BACK; 1.
DR SMART; SM00225; BTB; 1.
DR SMART; SM00612; Kelch; 6.
DR SUPFAM; SSF117281; Kelch motif; 1.
DR SUPFAM; SSF54695; POZ domain; 1.
DR PROSITE; PS50097; BTB; 1.
PE 4: Predicted;
KW Kelch repeat {ECO:0000256|ARBA:ARBA00022441};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 46..114
FT /note="BTB"
FT /evidence="ECO:0000259|PROSITE:PS50097"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE73575.1"
SQ SEQUENCE 589 AA; 66002 MW; FDD773812105467A CRC64;
MSVSVHENRK SRTSTGSMNI LLFHKASHSD CVLSHLNTMR KHCMFTDVTL SAGDKSFSCH
RAVLAASSRY FEAMFSNGLR ESLGDEVNFH DSLHPEVLEL LLDYAYSSKI IINEENAESL
LEAGDMLQFH DVRDAAAEFL EKNLCPSNCL GMMVLSDAHQ CKRLYEFSWR MCLVNFETIH
RTDEFNNLSK DTLLDLISSD ELEVEDEEKV FKAVIHWVKY DLDKRKPFFP ELLKNVRLAL
LPSECLKEAM AYEELITTEE ENKEIMGEAL WCKKKILQND GVVTSPCAKP RKAGHTLLIL
GGQTFMCDKV YQVDHKAKEI IPKSDLPSPR KEFSACAIGC KVYITGGRGS ENGVSKDVWV
YDTVNEEWSK AAPMLIARFG HGSAELENCL YVVGGHTAVA GVFPASPSVS LKQGEKYDPV
VNKWTMVAPL RDGVSNAAVV SARLKLYVFG GTSIHRDMVS KVQCYDPTEN RWTIKAECPQ
PWRYTAAAVL GSQIFIMGGD TEYTAASAYR FNCETDQWTR IGDMTAKRMS CHALASGNKL
YVVGGYFGTQ RCKTLDCYDP TSDTWNCITT VPYSLIPTAF VSTWKHLPA
//
