ID V8PI13_OPHHA Unreviewed; 448 AA.
AC V8PI13;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 24-JAN-2024, entry version 35.
DE SubName: Full=Growth arrest-specific protein 7 {ECO:0000313|EMBL:ETE73970.1};
DE Flags: Fragment;
GN Name=Gas7 {ECO:0000313|EMBL:ETE73970.1};
GN ORFNames=L345_00188 {ECO:0000313|EMBL:ETE73970.1};
OS Ophiophagus hannah (King cobra) (Naja hannah).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera;
OC Serpentes; Colubroidea; Elapidae; Elapinae; Ophiophagus.
OX NCBI_TaxID=8665 {ECO:0000313|EMBL:ETE73970.1, ECO:0000313|Proteomes:UP000018936};
RN [1] {ECO:0000313|EMBL:ETE73970.1, ECO:0000313|Proteomes:UP000018936}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Blood {ECO:0000313|EMBL:ETE73970.1};
RX PubMed=24297900; DOI=10.1073/pnas.1314702110;
RA Vonk F.J., Casewell N.R., Henkel C.V., Heimberg A.M., Jansen H.J.,
RA McCleary R.J., Kerkkamp H.M., Vos R.A., Guerreiro I., Calvete J.J.,
RA Wuster W., Woods A.E., Logan J.M., Harrison R.A., Castoe T.A.,
RA de Koning A.P., Pollock D.D., Yandell M., Calderon D., Renjifo C.,
RA Currier R.B., Salgado D., Pla D., Sanz L., Hyder A.S., Ribeiro J.M.,
RA Arntzen J.W., van den Thillart G.E., Boetzer M., Pirovano W., Dirks R.P.,
RA Spaink H.P., Duboule D., McGlinn E., Kini R.M., Richardson M.K.;
RT "The king cobra genome reveals dynamic gene evolution and adaptation in the
RT snake venom system.";
RL Proc. Natl. Acad. Sci. U.S.A. 110:20651-20656(2013).
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETE73970.1}.
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DR EMBL; AZIM01000017; ETE73970.1; -; Genomic_DNA.
DR AlphaFoldDB; V8PI13; -.
DR Proteomes; UP000018936; Unassembled WGS sequence.
DR CDD; cd07649; F-BAR_GAS7; 1.
DR CDD; cd00201; WW; 1.
DR Gene3D; 2.20.70.10; -; 1.
DR Gene3D; 1.20.1270.60; Arfaptin homology (AH) domain/BAR domain; 1.
DR InterPro; IPR027267; AH/BAR_dom_sf.
DR InterPro; IPR031160; F_BAR.
DR InterPro; IPR001060; FCH_dom.
DR InterPro; IPR037957; GAS7_F-BAR.
DR InterPro; IPR001202; WW_dom.
DR InterPro; IPR036020; WW_dom_sf.
DR PANTHER; PTHR23065:SF57; GROWTH ARREST-SPECIFIC PROTEIN 7; 1.
DR PANTHER; PTHR23065; PROLINE-SERINE-THREONINE PHOSPHATASE INTERACTING PROTEIN 1; 1.
DR Pfam; PF00611; FCH; 1.
DR Pfam; PF00397; WW; 1.
DR Pfam; PF16623; WW_FCH_linker; 1.
DR SMART; SM00055; FCH; 1.
DR SUPFAM; SSF103657; BAR/IMD domain-like; 1.
DR SUPFAM; SSF51045; WW domain; 1.
DR PROSITE; PS51741; F_BAR; 1.
DR PROSITE; PS50020; WW_DOMAIN_2; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|PROSITE-ProRule:PRU01077, ECO:0000256|SAM:Coils};
KW Reference proteome {ECO:0000313|Proteomes:UP000018936}.
FT DOMAIN 30..57
FT /note="WW"
FT /evidence="ECO:0000259|PROSITE:PS50020"
FT DOMAIN 168..428
FT /note="F-BAR"
FT /evidence="ECO:0000259|PROSITE:PS51741"
FT REGION 18..38
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 77..108
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..144
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 280..339
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 80..108
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT NON_TER 1
FT /evidence="ECO:0000313|EMBL:ETE73970.1"
SQ SEQUENCE 448 AA; 51519 MW; 368971CEFD9CF2B1 CRC64;
MSISLEFLCK NGSEKPRKVI PQVGEDSQNG HLPPGWQSYM SPQGRRYYVN TFTNETSASS
LSPSIGKVGD GICEETTWER PSSVPGTPKN SVSQKNSLPT VNGYHIPGTL ASQLEPSHMS
LRKISSDPQS PGSPSPTRKQ NKENTFTINC VTFPHPDTMP EQQLLKPSEW SYCDYFWTDK
KDPQGNSTVS GFEILLQKQL KGKQMQKEMA EFIRERIKIE EEYAKNLSKL SQNSLAAQEE
GTLGESWSQL KKSMADEAEV HLKFSSKLQA EVEKPLLNFR ENFKKDMKKY DHHIADLRKQ
LVSRYAAVEK ARKALTERQK DLEMKTQQLE IKLSNKTEEE IKKARRKSTQ AGDDLMRCVD
LYNQAQSKWF EEMVTTSLEL ERLEVERVEM IRQHLCQYTQ LRHETDMFNQ STVEPVDQLL
QKVDPAKDRE LWVKEHKTGN IRPVDMEI
//
