ID V9ELP2_PHYPR Unreviewed; 4556 AA.
AC V9ELP2;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 44.
DE RecName: Full=AAA+ ATPase domain-containing protein {ECO:0000259|SMART:SM00382};
GN ORFNames=F443_14353 {ECO:0000313|EMBL:ETI40180.1};
OS Phytophthora parasitica P1569.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI40180.1, ECO:0000313|Proteomes:UP000018721};
RN [1] {ECO:0000313|EMBL:ETI40180.1, ECO:0000313|Proteomes:UP000018721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1569 {ECO:0000313|EMBL:ETI40180.1,
RC ECO:0000313|Proteomes:UP000018721};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P1569.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI40180.1}.
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DR EMBL; ANIZ01002484; ETI40178.1; -; Genomic_DNA.
DR EMBL; ANIZ01002484; ETI40179.1; -; Genomic_DNA.
DR EMBL; ANIZ01002484; ETI40180.1; -; Genomic_DNA.
DR EnsemblProtists; ETI40178; ETI40178; F443_14353.
DR EnsemblProtists; ETI40179; ETI40179; F443_14353.
DR EnsemblProtists; ETI40180; ETI40180; F443_14353.
DR eggNOG; KOG3595; Eukaryota.
DR HOGENOM; CLU_000038_9_0_1; -.
DR OrthoDB; 166463at2759; -.
DR Proteomes; UP000018721; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0030286; C:dynein complex; IEA:UniProtKB-KW.
DR GO; GO:0005874; C:microtubule; IEA:UniProtKB-KW.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0045505; F:dynein intermediate chain binding; IEA:InterPro.
DR GO; GO:0051959; F:dynein light intermediate chain binding; IEA:InterPro.
DR GO; GO:0008569; F:minus-end-directed microtubule motor activity; IEA:InterPro.
DR GO; GO:0007018; P:microtubule-based movement; IEA:InterPro.
DR Gene3D; 1.10.287.2620; -; 1.
DR Gene3D; 1.10.472.130; -; 1.
DR Gene3D; 1.10.8.1220; -; 1.
DR Gene3D; 1.10.8.710; -; 1.
DR Gene3D; 1.20.1270.280; -; 1.
DR Gene3D; 1.20.58.1120; -; 1.
DR Gene3D; 1.20.920.20; -; 1.
DR Gene3D; 1.20.920.30; -; 1.
DR Gene3D; 3.10.490.20; -; 1.
DR Gene3D; 6.10.140.1060; -; 1.
DR Gene3D; 1.20.140.100; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.20.180.20; Dynein heavy chain, N-terminal domain 2; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 5.
DR Gene3D; 1.10.8.720; Region D6 of dynein motor; 1.
DR InterPro; IPR003593; AAA+_ATPase.
DR InterPro; IPR035699; AAA_6.
DR InterPro; IPR035706; AAA_9.
DR InterPro; IPR041658; AAA_lid_11.
DR InterPro; IPR042219; AAA_lid_11_sf.
DR InterPro; IPR026983; DHC_fam.
DR InterPro; IPR041589; DNAH3_AAA_lid_1.
DR InterPro; IPR042222; Dynein_2_N.
DR InterPro; IPR043157; Dynein_AAA1S.
DR InterPro; IPR041466; Dynein_AAA5_ext.
DR InterPro; IPR041228; Dynein_C.
DR InterPro; IPR043160; Dynein_C_barrel.
DR InterPro; IPR024743; Dynein_HC_stalk.
DR InterPro; IPR024317; Dynein_heavy_chain_D4_dom.
DR InterPro; IPR004273; Dynein_heavy_D6_P-loop.
DR InterPro; IPR013602; Dynein_heavy_linker.
DR InterPro; IPR013594; Dynein_heavy_tail.
DR InterPro; IPR042228; Dynein_linker_3.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10676:SF183; DYNEIN AXONEMAL HEAVY CHAIN 2; 1.
DR PANTHER; PTHR10676; DYNEIN HEAVY CHAIN FAMILY PROTEIN; 1.
DR Pfam; PF12774; AAA_6; 1.
DR Pfam; PF12775; AAA_7; 1.
DR Pfam; PF12780; AAA_8; 1.
DR Pfam; PF12781; AAA_9; 1.
DR Pfam; PF17857; AAA_lid_1; 1.
DR Pfam; PF18198; AAA_lid_11; 1.
DR Pfam; PF08385; DHC_N1; 1.
DR Pfam; PF08393; DHC_N2; 1.
DR Pfam; PF17852; Dynein_AAA_lid; 1.
DR Pfam; PF18199; Dynein_C; 1.
DR Pfam; PF03028; Dynein_heavy; 1.
DR Pfam; PF12777; MT; 1.
DR SMART; SM00382; AAA; 2.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 4.
PE 4: Predicted;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Dynein {ECO:0000256|ARBA:ARBA00023017};
KW Microtubule {ECO:0000256|ARBA:ARBA00022701};
KW Motor protein {ECO:0000256|ARBA:ARBA00023175};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000018721}.
FT DOMAIN 1903..2040
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT DOMAIN 2517..2663
FT /note="AAA+ ATPase"
FT /evidence="ECO:0000259|SMART:SM00382"
FT REGION 966..1026
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 3117..3151
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3176..3225
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3340..3416
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 3652..3679
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 966..985
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1002..1016
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 4556 AA; 516579 MW; 3B24A3B804DF1277 CRC64;
MSSFEDVELI AQWIRDRITL PGYQPKAWTS ADLATVKEFA ESTGVPALFL TVQNDSLVVM
TTAPRHFSSV MYFVKNGQTL VTPANIKDAL QYGTVEKDAI SSLLHLMNGY YLQRLQANKS
WPESVQKEFT GQFFRFMSSL TETVSRGCGK TVLYLPPVNP DKFNYKDKDL VQQLESTVIH
WTRQIKEVIN NQDNAHDAEG AGPLEEIKFW EHRTQDLSGI TDQLNRDGVK EIVEILRAAK
SSYLQPFETL SQIIKQGSTE ANDNLRFLQK LSPVCEDIAR AQPDEIPLLL PKLLNFIRLI
WMYSRHYNTE DRITSLLRKV SNEIIIVCCK KISLPDVFDG NVEASVRHLE QSIQCGVSWK
QIYRKASHAV NTTAPSPDRR WNFDETGIFA QIDAFVQRCR ELLEVCEGQI QFARKGKDGK
REDLPTFGGN RGMDIVKSLR GIEAQFEGHV ERLRQLDYDI LDVKNTSWHS DFNSFKNGMK
DLEAMTQNVI NGAFESVSTV AAGVDMIGSF QKIAQREAIK RCVEKRTIDI FGMFKANIAS
IRNLFEKNKH APLLSPTEPQ FAGAALWARS LLLRATDDLV RLQELVDPSN AAECDEAQNA
YDGLRLVINE YIQRKYHDWI EDLNTLGNTN MNSRLENPLM TKTGADSDAV PASVNLNSHN
KDTNALQNTE KTLIGRAKKG FLHCNFDRPL LNLFAEVHYW QYFNGEIQIP YMAHDICNQK
EQLRVLREHV MLVVRDYNRI LLDLSSTERR LFEDIIRKLD RRIQPGLQKL TWVSKGIVEW
YVADCRKHCE TTYKIVQEFQ ENKDIVMKNC KMISGLMHIF IERNTIYDDG VFEAKQVIHR
KTIEKQLREA YQTISSTMTA SYEHFASGPP EVQREWNRFV ERSDKMLEDA LRQSVKKSLQ
ELSKAINGDA KTDPRPLFRI HVVLEDNKVE FKPFMADLTL MVNTVAKEIF NVISVVPRLV
ASLPQQHSNN QVNADNSTTS DAPADGKNDS KGGEEVRAPA TTSGEPTGNQ DETLSTVDTP
DKADAPPVVN NFYQSIFNDE EILKVLVHIM NGMSSSATEL QKYLGYWDKY KLVWNQDKQA
FIRRYAKANR PLQQFRADIE RYREQQVSIQ NEDLTNTINF IQIDTNFLKA SLVEHTVQWI
GKLTGLLNQT AHGELKELMN MMKDNTQKLQ IKPLNLDHLS ESIHLLQDIK EGMPGVVARF
EPLQHKYDLL AEFDVQTTDE EQRDLANLKA NWETYEAMLV DANTMLQKCK VSMKQSLQDS
VADLNNIMSE LRTEAEATLP YSGEQQSKIA HQILADFEKK MEATRSRQNA LKKGLEIFGI
DESKNDGFVQ TEKELELLQQ IWALTDEWEV VWASWKNKVF YEIEVDTMES TAAQFFKKVV
KYGKDMKNWA VWSSMKTKIE QFRQTLPLIQ DLKSPALRAR HWAQLKEEMG KTFDTESTSF
TLERVFSLGF HLHAEFISTL SSNAGKELSI EQTLDAIEKR WATIDVDITE YKGVYYKIRS
ADDLFTALED DQVQLSTMKA SPFFGSFDTR ILYWEKALSH LSDVIETLLG VQRCWIYLES
IFMASEDIRK QLPLESQLFD EVNAAYCKVT EGMAKTKNAL QATQEAGVLE TLVTMQEKLD
QIQKCLDQYL ETKRMLFPRF YFLSNDDLLE ILGHQKDPDQ VQKHIKKCFE AIKTLNLIPP
GARGNTTFEA LGMNSPCGEQ VVFASNVVVA GAVEGWLLRI EAAMVNTLEK IFAQCIVGYK
GKKEKWIKDF PGQLLITCGQ TAWTNECIKA LNEVAKGEKK ALRQLKKKWI SYLNKLADMV
RGQLSATDRR KVVAVITTEI HSRDVIDRLV KQNCKSVNDF DWLMQLRFYF NKDLGESGIC
EVKQTVTSLQ YSYEYQGNNG RLVITPLTDR CVLTMTTALH LNRGGNPLGP AGTGKTETVK
DLGKNLAKYV IVFNCSDGLD YKSVGRMFAG LVQSGGWGCF DEFNRIEIEV LSVVAQQVLT
IMQALTARST QVMFLGSMMR VNFNMGIFIT MNPGYAGRTE LPDNLKALMR PCAMMVPDLA
LIAEVMLQAE GFRDAKVLAK KTTTLYGLMI QQLSKQDHYD FGLRSLKAVL NMAGTLKRED
PNLQEENILL RALRDMNMPK FIREDAVLFR LLLGDLFPSI ELPVTDYGKL QGNIEQALLE
TKLQVHPVIV FKTIQLYESQ VTRHCNMIVG QTMAGKTTIW KTLMAAKTSL AKDGVPGYMP
VRVQVLNPKS ISLNEIYGVY DLATFEWIDG ILSAIFRNLA ADEKAEEKWI MLDGPVDTLW
IESMNSVMDD NKVLTLINGD RISMSPSMAL MFEVQDLAVA SPATVSRAGM VYMDVEDLGW
RPFIQTWLTT TISIQEERDV LQALFDKYME KVLRFKTFEV TELIPVTTFN CVKSFCNLYN
ALGTAENGVD LAACGDKFAV TVEKWFLFCM TWSVMAAANE EGRKKFDFFL RDIDSVYPPL
KTAYDFFVEP SSREFKLWDE KLPPNFRIAP NTPFHKIMVP TIDTLRYGYL LQTMLTAGIH
TLLVGETGVG KTTVIEREIE ALSDAYNVLV MNFSSATSSA TTQDMIENVM EKRSLNRFGP
VGGRKLVTFI DDMNMPTKDL FGSQPPLELL RQWVDYSCWY DRKKQTLKYF IDMQFVAAMG
PPGGGRSVIS SRFQSRFNLI NMTIPEQAQL KRIFETMLVP KLAEFDDEIK PLGVPLVAAT
IQLYQNVLEQ FLPTPANCHY LFNLRDMARV IQGLLLSDKH TVASRDGMLR LWMHESLRVF
SDRLTSYEDR QSFKKKLDDL LGVHFQTDWS RLLSSAPEQL KENGPLFTYI FSTTPGSDEG
SARYAEVMDM KMLKNFVEEQ LENHNAEPGF VPMNLVMFSD ALMHILRIHR QLMTMRGNLL
LVGVGGSGRQ SLTKLAAFMG GFKVFQIEVG KNYRSFEFHE DIKKLYTQVG LQQQKTVFLF
SDTQIKSESF VEDLNNILSS GEIPGLFEKD EQAGILDGVR LRARAQGIRE TKESLWNFFI
SEVRRNLHVV LAFSPIGKGF CNRCRQFPSL VNNTNIDWFN EWPLDALQEV GMKFLEEKNV
AVETQRPKIA AVFAVVHSSV MLASSQVLAR MKRHNYVTPT NYLSLVTGYV ELLSEKAATI
RDTRDKLKNG LAKLEESRLQ VEEMSKQLEQ RKIVVAQKNK DCSDLLVVIV SERRVADEQR
KQVEADSERI GKEEAETKKI ADDAQKDLDE ALPALQRAMQ EVENLDKKAI AEVKVYTQPP
EAVSMVMCAV MILFGLPPTW ASAKTKMNDV SFLQQIKTFD KDSIRDKTVT ALKKYTSKPT
FNADVVRKVS SAAGALCSWV LAMECYAGVF RVVAPKKEVL RKSQQALAIK QKDLQVAKEK
LQEVTEKVEA LKNQYDTSVS EKNALREEAE LLELKLSRAE QLVKGLAGER ERWEASIADK
NASLQNVVGD ALVAAAFISY AGPFDTFYRG SLVDTWMNRV TQQALPLSPK FTFIDFLADP
TDVRSWNAHG LPRDPLSTEN GVITTRGKRW PLMIDPQGQA NKWIKAMEGT RLEVVDPMMK
DLLRKLENGI RFGSPVLMQD ILEDLDPSLE PVLTKSIIKV GNREVLRLGD KELDYNREFR
FYLTTKLHNP HYTPEVSTKT TIVNFVVKEQ GLEAQLLGIA VQLEEPALEE QKSDLVMRVA
AAKKKLIDLE NEILRLLSAA KGSLLDDEQL VTTLNASKTT SEEVSMQLVI SEETEKKIDA
ARMGYARVAL RSSTLYFVLN DMTSVDPMYQ FSLDAYVALF QDSIVKSRSL KNQGALSEEL
TERINAINDY HTYAVYAYAC RGLFERHKLL FSLQMCARVL QSINKLPHDE YDFLLKGGNV
LAQEEKVPNV ANEFLSDGSW ASIVELNKLS AFHGIISSFE QTLKGWKAWY QSSTPEIEAL
PGDWEGKCNE LQRMLLLRCV RPDRLSIQAA RFTATHLGAQ FVDPPPFDLK AIYDTSNYKT
PLIFVLSPGV DPTNSLIALA ESLHKTVENC ALGQGQASVA EAMLARGLDA GNWVFLANCH
LMLSWAPTLE KLIDNFCAAA PAPAGSVNPQ FRLWLTSSPN PKFPIAILQR GIKMTTEPPR
GLKANLIRLY NTITPEKFTR CRQVKKYKRL LFCLCWFHSL LLERRKFNNL GWNIPYDFNE
SDFAISEDVL AIYLDEYEDT PWDALKYLIA QANYGGRVTD DWDRRLMLVY ISQFFCENVL
TVDNMPLSDS EYYFVPDDGD LSSYTEYIRQ LPLDDPPAAF GQHPNAQIAS QIDDGRELLA
TILSLQALDV AEGGSGNDDT VLGLLQTLRE TVPDVFDLAN IKAGLSARSD PDALKTVLMQ
ELERYNKLLA TINSSARALE KGIQGSVVIT PELEAVYNAL LIGAVPKAWS FCYPSLKPLG
PWTQDLKLRC EQMDRWANQA HPAVFWLTGF TYPTGFLTAL LQTAARKNGL AIDSLNWEFI
VLNQGENALP TGPKDGAYIK GLILEGARWD FDHDCLAEPH PMELHCAMPI LHFRPVEAKK
KSAKGLYSCP LYMYPLRTGT RERPSFMIAV DLKVGPGKTP DLWTKRGTAL LLSLST
//
