ID   V9ELQ7_PHYPR            Unreviewed;       740 AA.
AC   V9ELQ7;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 29.
DE   RecName: Full=TIR domain-containing protein {ECO:0000259|Pfam:PF13676};
GN   ORFNames=F443_15372 {ECO:0000313|EMBL:ETI38997.1};
OS   Phytophthora parasitica P1569.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI38997.1, ECO:0000313|Proteomes:UP000018721};
RN   [1] {ECO:0000313|EMBL:ETI38997.1, ECO:0000313|Proteomes:UP000018721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P1569 {ECO:0000313|EMBL:ETI38997.1,
RC   ECO:0000313|Proteomes:UP000018721};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P1569.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETI38997.1}.
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DR   EMBL; ANIZ01002697; ETI38997.1; -; Genomic_DNA.
DR   AlphaFoldDB; V9ELQ7; -.
DR   EnsemblProtists; ETI38997; ETI38997; F443_15372.
DR   eggNOG; ENOG502QVY7; Eukaryota.
DR   HOGENOM; CLU_009381_0_0_1; -.
DR   OrthoDB; 51031at2759; -.
DR   Proteomes; UP000018721; Unassembled WGS sequence.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   Gene3D; 3.40.50.10140; Toll/interleukin-1 receptor homology (TIR) domain; 1.
DR   InterPro; IPR000157; TIR_dom.
DR   InterPro; IPR035897; Toll_tir_struct_dom_sf.
DR   InterPro; IPR001562; Znf_Btk_motif.
DR   PANTHER; PTHR46270; ARMADILLO-TYPE FOLD-RELATED; 1.
DR   PANTHER; PTHR46270:SF6; TIR DOMAIN-CONTAINING PROTEIN; 1.
DR   Pfam; PF13676; TIR_2; 1.
DR   SUPFAM; SSF52200; Toll/Interleukin receptor TIR domain; 1.
DR   PROSITE; PS51113; ZF_BTK; 1.
PE   4: Predicted;
KW   Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00432};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018721};
KW   Zinc {ECO:0000256|PROSITE-ProRule:PRU00432};
KW   Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00432}.
FT   DOMAIN          467..553
FT                   /note="TIR"
FT                   /evidence="ECO:0000259|Pfam:PF13676"
SQ   SEQUENCE   740 AA;  81138 MW;  19C39A9861A66A0B CRC64;
     MGSAASTSSE GGSGKPHAVV VCHSSQKDSL RGLLKDGGEI NNVDDVVIIT DSYPRDRQQR
     AGIISRVQTA FVAIDPMLQR SSELIETLSY LKDQRKTVIS GQLTFFSRPS GAIGAVCLTL
     NQWDPLLFAE PSRLAYWAEK YALLTRSEAN DIDDTSDELE GVNVNTSCAV ETSLSPHIFF
     VFCIDDTGES ERVIEKFAHA KLVPGGISLD GEVIRCQHNI QSDLTALREA SVVVFVITEA
     CTAEDDNAMC FRQLFEHALA WNIPLLPIKE QRASLRGWLA LAMAGRLWYQ VDATNLELVD
     TPYANIPDCP CKVKDSCLAT DFVVCANGLL LAPHRTLERS QIASRENAAI SIAKERAQVL
     GLSSIAIGSL CRRVGELVNP GDDDSIRSLD ELGVATTREA VEIEATGHLD EPKPVDLLPA
     EQTEETKSLQ PLSDIHYEVT RQGFVAPPAV LNNDGQPIIG LQLDAMFSYQ WGSQHTVLKI
     HQQGQVHNLR AWFDVYGHMQ GNVNSAMAAA VESVACMVVF LTKAYLVSVN CHLEFAYATR
     CRKPMIFAFL EDPETLDLPD WVVDVAGTTQ FNVYPSLVKE SLDEPSRVLA LDMRAERVRG
     VPITDVLFGA IRKLAACRAN SSVPIVYDGS LLLYATTSAL HYALENEKRD NKSEGTGVRS
     ETTVCTRCGA AFVYEITASL EGCRRHTAYY VGGTLIAGRW ACCQETDRDG PGCQQAQHMA
     AGRIWTMEPS YGTYTYEPNP
//