ID V9F2Q5_PHYPR Unreviewed; 223 AA.
AC V9F2Q5;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 13-SEP-2023, entry version 32.
DE RecName: Full=DOT1 domain-containing protein {ECO:0000259|Pfam:PF08123};
GN ORFNames=F443_09742 {ECO:0000313|EMBL:ETI45804.1};
OS Phytophthora parasitica P1569.
OC Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC Phytophthora.
OX NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI45804.1, ECO:0000313|Proteomes:UP000018721};
RN [1] {ECO:0000313|EMBL:ETI45804.1, ECO:0000313|Proteomes:UP000018721}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=P1569 {ECO:0000313|EMBL:ETI45804.1,
RC ECO:0000313|Proteomes:UP000018721};
RG The Broad Institute Genomics Platform;
RA Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA Wortman J., Nusbaum C., Birren B.;
RT "The Genome Sequence of Phytophthora parasitica P1569.";
RL Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC -!- SIMILARITY: Belongs to the ANT/ATPSC lysine N-methyltransferase family.
CC {ECO:0000256|ARBA:ARBA00010633}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:ETI45804.1}.
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DR EMBL; ANIZ01001670; ETI45804.1; -; Genomic_DNA.
DR AlphaFoldDB; V9F2Q5; -.
DR EnsemblProtists; ETI45804; ETI45804; F443_09742.
DR eggNOG; KOG4058; Eukaryota.
DR HOGENOM; CLU_068443_2_1_1; -.
DR OrthoDB; 2963877at2759; -.
DR Proteomes; UP000018721; Unassembled WGS sequence.
DR GO; GO:0031151; F:histone H3K79 methyltransferase activity; IEA:InterPro.
DR GO; GO:0032259; P:methylation; IEA:UniProtKB-KW.
DR CDD; cd02440; AdoMet_MTases; 1.
DR Gene3D; 3.40.50.150; Vaccinia Virus protein VP39; 1.
DR InterPro; IPR025789; DOT1_dom.
DR InterPro; IPR026170; FAM173A/B.
DR InterPro; IPR000048; IQ_motif_EF-hand-BS.
DR InterPro; IPR029063; SAM-dependent_MTases_sf.
DR PANTHER; PTHR13610:SF11; METHYLTRANFER_DOM DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR13610; UNCHARACTERIZED; 1.
DR Pfam; PF08123; DOT1; 1.
DR SUPFAM; SSF53335; S-adenosyl-L-methionine-dependent methyltransferases; 1.
DR PROSITE; PS50096; IQ; 1.
PE 3: Inferred from homology;
KW Methyltransferase {ECO:0000256|ARBA:ARBA00022603};
KW Reference proteome {ECO:0000313|Proteomes:UP000018721};
KW S-adenosyl-L-methionine {ECO:0000256|ARBA:ARBA00022691};
KW Transferase {ECO:0000256|ARBA:ARBA00022679}.
FT DOMAIN 45..127
FT /note="DOT1"
FT /evidence="ECO:0000259|Pfam:PF08123"
SQ SEQUENCE 223 AA; 25015 MW; 422922A3C12E651B CRC64;
MSVSVAVGGV VKLQALFRGN KSRRIHVERA RNNLPWSPFV PAKLEAVYAI LEVANLQPGE
ILVDIGSGDG RVVIEAAVQC PELKRARGVE LDEALVGLSR RRIIERAEQE EIQGIQRPEQ
EFSREKKVDG ATALRGRVEI VHADFMEVDM KDADVVVLFF LPHKEISRTL HEKLRPGVRV
VTYVFQIPQW KPEKVVSTVP FMTAKGTSSI YLYLVPNTPQ VQL
//
