ID   V9FKV1_PHYPR            Unreviewed;       539 AA.
AC   V9FKV1;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   13-SEP-2023, entry version 30.
DE   RecName: Full=Glycosyl hydrolase family 30 TIM-barrel domain-containing protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=F443_04990 {ECO:0000313|EMBL:ETI51716.1};
OS   Phytophthora parasitica P1569.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI51716.1, ECO:0000313|Proteomes:UP000018721};
RN   [1] {ECO:0000313|EMBL:ETI51716.1, ECO:0000313|Proteomes:UP000018721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P1569 {ECO:0000313|EMBL:ETI51716.1,
RC   ECO:0000313|Proteomes:UP000018721};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P1569.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the glycosyl hydrolase 30 family.
CC       {ECO:0000256|ARBA:ARBA00005382}.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETI51716.1}.
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DR   EMBL; ANIZ01000889; ETI51716.1; -; Genomic_DNA.
DR   AlphaFoldDB; V9FKV1; -.
DR   EnsemblProtists; ETI51716; ETI51716; F443_04990.
DR   eggNOG; KOG2566; Eukaryota.
DR   HOGENOM; CLU_014379_1_2_1; -.
DR   OrthoDB; 5471004at2759; -.
DR   Proteomes; UP000018721; Unassembled WGS sequence.
DR   GO; GO:0004348; F:glucosylceramidase activity; IEA:InterPro.
DR   GO; GO:0006665; P:sphingolipid metabolic process; IEA:InterPro.
DR   Gene3D; 3.20.20.80; Glycosidases; 1.
DR   Gene3D; 2.60.40.1180; Golgi alpha-mannosidase II; 1.
DR   InterPro; IPR033452; GH30_C.
DR   InterPro; IPR001139; Glyco_hydro_30.
DR   InterPro; IPR033453; Glyco_hydro_30_TIM-barrel.
DR   InterPro; IPR013780; Glyco_hydro_b.
DR   InterPro; IPR017853; Glycoside_hydrolase_SF.
DR   PANTHER; PTHR11069; GLUCOSYLCERAMIDASE; 1.
DR   PANTHER; PTHR11069:SF23; LYSOSOMAL ACID GLUCOSYLCERAMIDASE; 1.
DR   Pfam; PF02055; Glyco_hydro_30; 1.
DR   Pfam; PF17189; Glyco_hydro_30C; 1.
DR   PRINTS; PR00843; GLHYDRLASE30.
DR   SUPFAM; SSF51445; (Trans)glycosidases; 1.
DR   PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Reference proteome {ECO:0000313|Proteomes:UP000018721};
KW   Signal {ECO:0000256|ARBA:ARBA00022729, ECO:0000256|SAM:SignalP}.
FT   SIGNAL          1..23
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT   CHAIN           24..539
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel domain-
FT                   containing protein"
FT                   /evidence="ECO:0000256|SAM:SignalP"
FT                   /id="PRO_5004775186"
FT   DOMAIN          104..462
FT                   /note="Glycosyl hydrolase family 30 TIM-barrel"
FT                   /evidence="ECO:0000259|Pfam:PF02055"
FT   DOMAIN          465..528
FT                   /note="Glycosyl hydrolase family 30 beta sandwich"
FT                   /evidence="ECO:0000259|Pfam:PF17189"
SQ   SEQUENCE   539 AA;  60217 MW;  611E5497E0707E66 CRC64;
     MKVLAPVAVF ASSLLLAPNA VWAACSSWSS LYQDVLEGVC VCNATQCDTI VGDHANLKEG
     EVGIYTTAKA GARLKYTVGK IDASPVDEPT YTIDVSTQYQ TMLGFGGAFT DAAAINLYKL
     SPKLQQLALD QYFTEEGLQY NMARVPIGST DFSTRTYTYN EKVDDFKMTN FTIASDKAPF
     SNKIDLIQRA LNMTELKLFA SSWAPPLWMT RGDSVVDCKM KGKPGEKYWA ALALYYSKFF
     DAYKEEGINF WAMTVQNEPE KPPLAVSQWE TMRLTAEEER DFIKLNLGPL MAKNHPDLKI
     MANDDQKPGL LDRSAPFDDP ESKKYLSGLA FHWYQNLDFI LPGAGNFKNL EKFHKAHPDM
     FMLGTEACEG FLPGIIGTGK GPSLDNPKKA WKRAQNYARD IIENSNNMAA GWVDWNLFLD
     TDGGPNWAKN MVDAPILVDE QNGAEFYKQP MFYIMGHFSK FVPPGSKRIE FPKTETISDF
     HRCAFVTPDN QVVMQFLNRD DDPVSISVKQ TDSNTISLTI PPNSMSTVIL PASEDTKIL
//