ID   V9G280_PHYPR            Unreviewed;       701 AA.
AC   V9G280;
DT   19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT   19-FEB-2014, sequence version 1.
DT   27-MAR-2024, entry version 31.
DE   RecName: Full=RNase H type-1 domain-containing protein {ECO:0000259|PROSITE:PS50879};
DE   Flags: Fragment;
GN   ORFNames=F443_00786 {ECO:0000313|EMBL:ETI56817.1};
OS   Phytophthora parasitica P1569.
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Phytophthora.
OX   NCBI_TaxID=1317065 {ECO:0000313|EMBL:ETI56817.1, ECO:0000313|Proteomes:UP000018721};
RN   [1] {ECO:0000313|EMBL:ETI56817.1, ECO:0000313|Proteomes:UP000018721}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=P1569 {ECO:0000313|EMBL:ETI56817.1,
RC   ECO:0000313|Proteomes:UP000018721};
RG   The Broad Institute Genomics Platform;
RA   Russ C., Tyler B., Panabieres F., Shan W., Tripathy S., Grunwald N.,
RA   Machado M., Johnson C.S., Arredondo F., Hong C., Coffey M., Young S.K.,
RA   Zeng Q., Gargeya S., Fitzgerald M., Abouelleil A., Alvarado L.,
RA   Chapman S.B., Gainer-Dewar J., Goldberg J., Griggs A., Gujja S., Hansen M.,
RA   Howarth C., Imamovic A., Ireland A., Larimer J., McCowan C., Murphy C.,
RA   Pearson M., Poon T.W., Priest M., Roberts A., Saif S., Shea T., Sykes S.,
RA   Wortman J., Nusbaum C., Birren B.;
RT   "The Genome Sequence of Phytophthora parasitica P1569.";
RL   Submitted (NOV-2013) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:ETI56817.1}.
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DR   EMBL; ANIZ01000135; ETI56817.1; -; Genomic_DNA.
DR   AlphaFoldDB; V9G280; -.
DR   EnsemblProtists; ETI56817; ETI56817; F443_00786.
DR   eggNOG; KOG0017; Eukaryota.
DR   HOGENOM; CLU_000384_18_7_1; -.
DR   OrthoDB; 691538at2759; -.
DR   Proteomes; UP000018721; Unassembled WGS sequence.
DR   GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR   GO; GO:0003964; F:RNA-directed DNA polymerase activity; IEA:UniProtKB-KW.
DR   GO; GO:0004523; F:RNA-DNA hybrid ribonuclease activity; IEA:InterPro.
DR   Gene3D; 3.30.70.270; -; 3.
DR   Gene3D; 3.10.10.10; HIV Type 1 Reverse Transcriptase, subunit A, domain 1; 1.
DR   Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR   InterPro; IPR043502; DNA/RNA_pol_sf.
DR   InterPro; IPR043128; Rev_trsase/Diguanyl_cyclase.
DR   InterPro; IPR012337; RNaseH-like_sf.
DR   InterPro; IPR002156; RNaseH_domain.
DR   InterPro; IPR036397; RNaseH_sf.
DR   InterPro; IPR041373; RT_RNaseH.
DR   PANTHER; PTHR37984:SF7; INTEGRASE CATALYTIC DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR37984; PROTEIN CBG26694; 1.
DR   Pfam; PF17917; RT_RNaseH; 1.
DR   Pfam; PF13456; RVT_3; 1.
DR   SUPFAM; SSF56672; DNA/RNA polymerases; 1.
DR   SUPFAM; SSF53098; Ribonuclease H-like; 1.
DR   PROSITE; PS50879; RNASE_H_1; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000018721}.
FT   DOMAIN          589..701
FT                   /note="RNase H type-1"
FT                   /evidence="ECO:0000259|PROSITE:PS50879"
FT   REGION          1..21
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          38..63
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         701
FT                   /evidence="ECO:0000313|EMBL:ETI56817.1"
SQ   SEQUENCE   701 AA;  78566 MW;  9EDCD15B657D9DA3 CRC64;
     MVNVGTQTDF PDNDTQDASS ILVEPACSDQ ASERCAASQV AGVSEVPNDD TSSDEEPDTL
     VHETSGRAVE RLDSEYARVM QVTEENLKLE PGVYIHEGSE LMAQLRDQLS MLPELQDLNK
     QLRDILERHK VIFLGEGNAA PAPARGVICD LDVGGAKPVA QRPRSIAPHL AVKLSNYPLP
     LIDDLLIGFE GALWFMSLDM ASGFWAIRMT ERAKLISAFV CPFGHFQWGF VRLPPEEEAL
     VDPEVLDYLK LEPQDTEPSE MQIADGDHSE QSYPENHVTP LTDQMTVFKR NIPAPPQMGP
     VLGRSSYIDD IAHGAPTWDQ LCSDLDALLY RLRYWNISVS LPKSEFGKRT IPYLSHEIGA
     EGIRAVPKIV KGIEELPFPK TLKGIQSFLG SLNYYHKFIE EYLVVAAVLY ELTDEQIRAG
     RNLTQAKESF EILKRKIVSP RCFGIRTARG RQEHEGVIQP VRFAGRVRHD AELKYHIAEK
     EVLAVIRVLR TFKALIEGCP LVVYTRYSVL KWVIRSKTAD GRTVPWGVAL SQYDLDIRKV
     QKDEDGLSAI LGAGITPREH LDEIAESLIP AKGRIKAPPV VSIEMLEEDY QGVVLSYDGA
     AKTSTRRGSC GCILWRLPEW KIIEARGYIL DDVTVNDSEY YGLLHGLKLA REHEIQDLVV
     VGDSRIVIQQ VQGLISCNQP NLQRRLAECE VLRKKFKTVR L
//