ID V9GXY1_MOUSE Unreviewed; 228 AA.
AC V9GXY1;
DT 19-FEB-2014, integrated into UniProtKB/TrEMBL.
DT 19-FEB-2014, sequence version 1.
DT 27-MAR-2024, entry version 50.
DE SubName: Full=Acetyl-Coenzyme A carboxylase alpha {ECO:0000313|Ensembl:ENSMUSP00000139378.2};
DE Flags: Fragment;
GN Name=Acaca {ECO:0000313|Ensembl:ENSMUSP00000139378.2,
GN ECO:0000313|MGI:MGI:108451};
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090 {ECO:0000313|Ensembl:ENSMUSP00000139378.2, ECO:0000313|Proteomes:UP000000589};
RN [1] {ECO:0007829|PubMed:17242355}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=17242355; DOI=10.1073/pnas.0609836104;
RA Villen J., Beausoleil S.A., Gerber S.A., Gygi S.P.;
RT "Large-scale phosphorylation analysis of mouse liver.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:1488-1493(2007).
RN [2] {ECO:0000313|Ensembl:ENSMUSP00000139378.2, ECO:0000313|Proteomes:UP000000589}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000139378.2,
RC ECO:0000313|Proteomes:UP000000589};
RX PubMed=19468303; DOI=10.1371/journal.pbio.1000112;
RA Church D.M., Goodstadt L., Hillier L.W., Zody M.C., Goldstein S., She X.,
RA Bult C.J., Agarwala R., Cherry J.L., DiCuccio M., Hlavina W., Kapustin Y.,
RA Meric P., Maglott D., Birtle Z., Marques A.C., Graves T., Zhou S.,
RA Teague B., Potamousis K., Churas C., Place M., Herschleb J., Runnheim R.,
RA Forrest D., Amos-Landgraf J., Schwartz D.C., Cheng Z., Lindblad-Toh K.,
RA Eichler E.E., Ponting C.P.;
RT "Lineage-specific biology revealed by a finished genome assembly of the
RT mouse.";
RL PLoS Biol. 7:E1000112-E1000112(2009).
RN [3] {ECO:0007829|PubMed:21183079}
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=21183079; DOI=10.1016/j.cell.2010.12.001;
RA Huttlin E.L., Jedrychowski M.P., Elias J.E., Goswami T., Rad R.,
RA Beausoleil S.A., Villen J., Haas W., Sowa M.E., Gygi S.P.;
RT "A tissue-specific atlas of mouse protein phosphorylation and expression.";
RL Cell 143:1174-1189(2010).
RN [4] {ECO:0000313|Ensembl:ENSMUSP00000139378.2}
RP IDENTIFICATION.
RC STRAIN=C57BL/6J {ECO:0000313|Ensembl:ENSMUSP00000139378.2};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; V9GXY1; -.
DR SMR; V9GXY1; -.
DR MaxQB; V9GXY1; -.
DR PeptideAtlas; V9GXY1; -.
DR ProteomicsDB; 357684; -.
DR Antibodypedia; 73364; 835 antibodies from 39 providers.
DR Ensembl; ENSMUST00000183887.2; ENSMUSP00000139378.2; ENSMUSG00000020532.19.
DR AGR; MGI:108451; -.
DR MGI; MGI:108451; Acaca.
DR VEuPathDB; HostDB:ENSMUSG00000020532; -.
DR GeneTree; ENSGT00940000156706; -.
DR HOGENOM; CLU_1217182_0_0_1; -.
DR ChiTaRS; Acaca; mouse.
DR Proteomes; UP000000589; Chromosome 11.
DR Bgee; ENSMUSG00000020532; Expressed in epididymal fat pad and 255 other cell types or tissues.
DR ExpressionAtlas; V9GXY1; baseline and differential.
DR GO; GO:0003989; F:acetyl-CoA carboxylase activity; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0006633; P:fatty acid biosynthetic process; IEA:InterPro.
DR InterPro; IPR049076; ACCA.
DR InterPro; IPR013537; AcCoA_COase_cen.
DR PANTHER; PTHR45728:SF5; ACETYL-COA CARBOXYLASE 1; 1.
DR PANTHER; PTHR45728; ACETYL-COA CARBOXYLASE, ISOFORM A; 1.
DR Pfam; PF08326; ACC_central; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|EPD:V9GXY1,
KW ECO:0007829|MaxQB:V9GXY1};
KW Reference proteome {ECO:0000313|Proteomes:UP000000589}.
FT DOMAIN 2..227
FT /note="Acetyl-CoA carboxylase central"
FT /evidence="ECO:0000259|Pfam:PF08326"
FT NON_TER 1
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000139378.2"
FT NON_TER 228
FT /evidence="ECO:0000313|Ensembl:ENSMUSP00000139378.2"
SQ SEQUENCE 228 AA; 26534 MW; 436BD8A4729C133B CRC64;
DNTCVVEFQF MLPTSHPNRM SFASNLNHYG MTHVASVSDV LLDNAFTPPC QRMGGMVSFR
TFEDFVRIFD EIMGCFCDSP PQSPTFPESG HTSLYDEDKV PRDEPIHILN VAIKTDGDIE
DDRLAAMFRE FTQQNKATLV EHGIRRLTFL VAQKDFRKQV NCEVDQRFHR EFPKFFTFRA
RDKFEEDRIY RHLEPALAFQ LELNRMRNFD LTAIPCANHK MHLYLGAA
//
