ID V9KTG9_CALMI Unreviewed; 472 AA.
AC V9KTG9;
DT 19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT 19-MAR-2014, sequence version 1.
DT 27-MAR-2024, entry version 36.
DE RecName: Full=Tetratricopeptide repeat protein 29 {ECO:0000256|ARBA:ARBA00040665};
GN Name=ttc29 {ECO:0000313|Ensembl:ENSCMIP00000019187.1};
OS Callorhinchus milii (Ghost shark).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes;
OC Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus.
OX NCBI_TaxID=7868 {ECO:0000313|EMBL:AFP01499.1};
RN [1] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17185593; DOI=10.1126/science.1130708;
RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J.,
RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L.,
RA Brenner S.;
RT "Ancient noncoding elements conserved in the human genome.";
RL Science 314:1892-1892(2006).
RN [2] {ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=17407382;
RA Venkatesh B., Kirkness E.F., Loh Y.H., Halpern A.L., Lee A.P., Johnson J.,
RA Dandona N., Viswanathan L.D., Tay A., Venter J.C., Strausberg R.L.,
RA Brenner S.;
RT "Survey sequencing and comparative analysis of the elephant shark
RT (Callorhinchus milii) genome.";
RL PLoS Biol. 5:E101-E101(2007).
RN [3] {ECO:0000313|EMBL:AFP01499.1, ECO:0000313|Proteomes:UP000314986}
RP NUCLEOTIDE SEQUENCE.
RC TISSUE=Testis {ECO:0000313|EMBL:AFP01499.1};
RX PubMed=24402279; DOI=10.1038/nature12826;
RG International Elephant Shark Genome Sequencing Consortium;
RA Venkatesh B., Lee A.P., Ravi V., Maurya A.K., Lian M.M., Swann J.B.,
RA Ohta Y., Flajnik M.F., Sutoh Y., Kasahara M., Hoon S., Gangu V., Roy S.W.,
RA Irimia M., Korzh V., Kondrychyn I., Lim Z.W., Tay B.H., Tohari S.,
RA Kong K.W., Ho S., Lorente-Galdos B., Quilez J., Marques-Bonet T.,
RA Raney B.J., Ingham P.W., Tay A., Hillier L.W., Minx P., Boehm T.,
RA Wilson R.K., Brenner S., Warren W.C.;
RT "Elephant shark genome provides unique insights into gnathostome
RT evolution.";
RL Nature 505:174-179(2014).
RN [4] {ECO:0000313|Ensembl:ENSCMIP00000019187.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (SEP-2023) to UniProtKB.
CC -!- FUNCTION: Axonemal protein which is implicated in axonemal and/or peri-
CC axonemal structures assembly and regulates flagella assembly and
CC beating and therefore sperm motility. {ECO:0000256|ARBA:ARBA00037175}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton, flagellum axoneme
CC {ECO:0000256|ARBA:ARBA00004611}.
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DR EMBL; JW868981; AFP01499.1; -; mRNA.
DR Ensembl; ENSCMIT00000019550.1; ENSCMIP00000019187.1; ENSCMIG00000008978.1.
DR GeneTree; ENSGT00390000008611; -.
DR Proteomes; UP000314986; Unassembled WGS sequence.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 1.
DR InterPro; IPR011990; TPR-like_helical_dom_sf.
DR InterPro; IPR019734; TPR_repeat.
DR PANTHER; PTHR46630; TETRATRICOPEPTIDE REPEAT PROTEIN 29; 1.
DR PANTHER; PTHR46630:SF1; TETRATRICOPEPTIDE REPEAT PROTEIN 29; 1.
DR Pfam; PF13174; TPR_6; 1.
DR Pfam; PF13181; TPR_8; 2.
DR SMART; SM00028; TPR; 4.
DR SUPFAM; SSF48452; TPR-like; 1.
DR PROSITE; PS50005; TPR; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Reference proteome {ECO:0000313|Proteomes:UP000314986};
KW TPR repeat {ECO:0000256|ARBA:ARBA00022803, ECO:0000256|PROSITE-
KW ProRule:PRU00339}.
FT REPEAT 192..225
FT /note="TPR"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ SEQUENCE 472 AA; 53671 MW; D9C37526BDF3346A CRC64;
MSILSAITGQ CPGGLPSLPL QQAICASAPS SQFPKPTYRI PTRQERIATA KRLKKQNEQS
RLSKYEVNVY RNSYKHNICL DMLREGYHRS FSELSALIHK LNAFREAEGP GSDIWQQKTL
EEQHEKLDKL QCFLTRAEAA QRAGLYEEVY NSQLSLACYF KGTEDKLLSD YFFETCLKTT
AMISSDERQK EAEANANLGL AYEEKGQLNK AVEHYEAFYQ LSVEKPWQDE DGCSHYAQAC
ENLWRIYTLL ADKMLECDKR REAIKTLIKA FEIAKEGGDR KMEGLAAYRV ALAYHANGDP
QTAIKYLQMY LKVSELLNDD FGLSKAYEAM SKALVSVGNI NEAIRYLEMF VEVAKRLSEK
RSLVDACKSL GVIYNTLGRY DLACEYISQA YDIAITLSDL PLLEIVQVHF GIAKAHSMMT
AVCRNIEAGK RVNLDRLVIW KNNRIDMFNE PITDAVDETF EDDASETAME KK
//
