ID   V9VSZ3_9RHOB            Unreviewed;      1139 AA.
AC   V9VSZ3;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 35.
DE   SubName: Full=MFS transporter {ECO:0000313|EMBL:AHD00799.1};
DE            EC=1.2.7.8 {ECO:0000313|EMBL:AHD00799.1};
GN   ORFNames=METH_09010 {ECO:0000313|EMBL:AHD00799.1};
OS   Leisingera methylohalidivorans DSM 14336.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodobacterales;
OC   Roseobacteraceae; Leisingera.
OX   NCBI_TaxID=999552 {ECO:0000313|EMBL:AHD00799.1, ECO:0000313|Proteomes:UP000018780};
RN   [1] {ECO:0000313|EMBL:AHD00799.1, ECO:0000313|Proteomes:UP000018780}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 14336 {ECO:0000313|EMBL:AHD00799.1,
RC   ECO:0000313|Proteomes:UP000018780};
RG   DOE Joint Genome Institute;
RA   Klenk H.-P., Huntemann M., Han J., Chen A., Kyrpides N., Mavromatis K.,
RA   Markowitz V., Palaniappan K., Ivanova N., Schaumberg A., Pati A.,
RA   Liolios K., Nordberg H.P., Cantor M.N., Hua S.X., Woyke T.;
RL   Submitted (SEP-2013) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; CP006773; AHD00799.1; -; Genomic_DNA.
DR   RefSeq; WP_024090057.1; NC_023135.1.
DR   AlphaFoldDB; V9VSZ3; -.
DR   STRING; 999552.METH_09010; -.
DR   KEGG; lmd:METH_09010; -.
DR   PATRIC; fig|999552.6.peg.1801; -.
DR   HOGENOM; CLU_009166_1_0_5; -.
DR   OrthoDB; 9803617at2; -.
DR   Proteomes; UP000018780; Chromosome.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:UniProtKB-KW.
DR   GO; GO:0043805; F:indolepyruvate ferredoxin oxidoreductase activity; IEA:UniProtKB-EC.
DR   GO; GO:0030976; F:thiamine pyrophosphate binding; IEA:InterPro.
DR   CDD; cd07034; TPP_PYR_PFOR_IOR-alpha_like; 1.
DR   Gene3D; 3.40.50.970; -; 2.
DR   Gene3D; 3.40.920.10; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   InterPro; IPR017896; 4Fe4S_Fe-S-bd.
DR   InterPro; IPR046667; DUF6537.
DR   InterPro; IPR019752; Pyrv/ketoisovalerate_OxRed_cat.
DR   InterPro; IPR002880; Pyrv_Fd/Flavodoxin_OxRdtase_N.
DR   InterPro; IPR002869; Pyrv_flavodox_OxRed_cen.
DR   InterPro; IPR029061; THDP-binding.
DR   InterPro; IPR011766; TPP_enzyme_TPP-bd.
DR   InterPro; IPR009014; Transketo_C/PFOR_II.
DR   PANTHER; PTHR48084:SF4; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB; 1.
DR   PANTHER; PTHR48084; 2-OXOGLUTARATE OXIDOREDUCTASE SUBUNIT KORB-RELATED; 1.
DR   Pfam; PF20169; DUF6537; 1.
DR   Pfam; PF01558; POR; 1.
DR   Pfam; PF02775; TPP_enzyme_C; 1.
DR   SUPFAM; SSF53323; Pyruvate-ferredoxin oxidoreductase, PFOR, domain III; 1.
DR   SUPFAM; SSF52518; Thiamin diphosphate-binding fold (THDP-binding); 2.
DR   SUPFAM; SSF52922; TK C-terminal domain-like; 1.
DR   PROSITE; PS51379; 4FE4S_FER_2; 1.
PE   4: Predicted;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Electron transport {ECO:0000256|ARBA:ARBA00022982};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022485};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002,
KW   ECO:0000313|EMBL:AHD00799.1}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   DOMAIN          626..657
FT                   /note="4Fe-4S ferredoxin-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51379"
SQ   SEQUENCE   1139 AA;  124704 MW;  9F735CDDAA37791F CRC64;
     MSTPKISLND KYDLTKSPVL LNGTQALVRL MLMQKHRDQA AGLNTAGLVT GYRGSPLGAV
     DLQMSKAEKH LKAADVTFQY GLNEDLAVTA LWGAQQAEVR GEGKYDGVFG LWYGKGPGVD
     RSGDAIRHAN MAGSSKHGGV LLAMGDDHTG ESSTVLHQSE WSLLDCYLPI VSPAGVQEIL
     DYGIYGYALS RFSGLWTGLK TMKDTIEVTS VVDARPERMQ LVTPEFDMPA DGLNIRLDDD
     RFRQEDRIID YKRFAAEAFS HANKMDKRMW GKPGAKIGFV AAGKNWLDLV HALKLLNIDE
     TMAERLGLTT YKVGQTWPMD MKGFHDWAED LDLIVVVEEK RKLIEIQIKE AIFDDRRGRR
     VYGWYKGGAG SLHREELFPT RYALDPIMIA EKLGGILIEE GRETEAIRAG LEGLSEARRA
     DNAEEIATRL PYFCSGCPHN SSTKLPEGSR AYAGIGCHFM VQWMDRETTG FTHMGGEGVN
     WVGEAPFSKR KHVFQNLGDG TYNHSGVQAI RAALAEGTNI TYKILYNDAV AMTGGQAAEG
     GLTAQQIAHE LTAMGVKTIA VVYDEKEDVN AALFPAGMRM HERAEMMKIQ REFEQVEGVS
     AIIYIQTCAA EKRRRRKKGQ FPDPDQRVFI NTDVCEGCGD CGVQSNCVSI VPKDTELGRK
     RAIDQSSCNK DFSCVNGFCP SFVTVEGARI RKEATADIDL PHLPKPQLPA IDGTHNVVIT
     GVGGTGVVTI GAVLAQAAQI DGLGAGLMEM AGLAQKGGAV HIHCRIAQKP EDISAIRVAT
     GEAHALIGGD LVVSAGAKTL GLTSTGRTGA VVNSHEIITG DFTRDTEFAI PTDRLQVALQ
     ARLRDRVDLF DASELARATM GDSIFSNMMV FGGAWQRGLV PVSHAAIEQA IEMNGAAVDR
     NKRAFDIGRW AVLHPEEAAR LMQPETVDKP KSLEEKIAFR ADQLVAYQGN GLARRYTSLV
     EGISDPALKE AVAKGYHKLL SYKDEYEVAR LLLDSRAKAE AEFEGDLKLS YHLAPPMLSG
     TDPNGRPKKR KFGAGMERGF RLLAKLKRLR GTPLDIFGYT AERKMERALI KQFEADMKEW
     LPKAAPAIME PLTALAELPL SIRGFGPVKM ANEQKAAKRR EELLAALRQG GVPMKEAAE
//