ID   V9W6H0_9BACL            Unreviewed;       469 AA.
AC   V9W6H0;
DT   19-MAR-2014, integrated into UniProtKB/TrEMBL.
DT   19-MAR-2014, sequence version 1.
DT   27-MAR-2024, entry version 38.
DE   SubName: Full=Putative multidrug resistance protein YoeA {ECO:0000313|EMBL:AHD05743.1};
GN   Name=yoeA {ECO:0000313|EMBL:AHD05743.1};
GN   ORFNames=ERIC2_c19470 {ECO:0000313|EMBL:AHD05743.1};
OS   Paenibacillus larvae subsp. larvae DSM 25430.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX   NCBI_TaxID=697284 {ECO:0000313|EMBL:AHD05743.1, ECO:0000313|Proteomes:UP000029431};
RN   [1] {ECO:0000313|EMBL:AHD05743.1, ECO:0000313|Proteomes:UP000029431}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 25430 {ECO:0000313|EMBL:AHD05743.1,
RC   ECO:0000313|Proteomes:UP000029431};
RX   PubMed=24599066;
RA   Djukic M., Brzuszkiewicz E., Funfhaus A., Voss J., Gollnow K., Poppinga L.,
RA   Liesegang H., Garcia-Gonzalez E., Genersch E., Daniel R.;
RT   "How to Kill the Honey Bee Larva: Genomic Potential and Virulence
RT   Mechanisms of Paenibacillus larvae.";
RL   PLoS ONE 9:E90914-E90914(2014).
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CP003355; AHD05743.1; -; Genomic_DNA.
DR   RefSeq; WP_024094137.1; NZ_CP019652.1.
DR   AlphaFoldDB; V9W6H0; -.
DR   KEGG; plv:ERIC2_c19470; -.
DR   PATRIC; fig|697284.3.peg.1867; -.
DR   eggNOG; COG0534; Bacteria.
DR   HOGENOM; CLU_012893_5_0_9; -.
DR   Proteomes; UP000029431; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0015297; F:antiporter activity; IEA:InterPro.
DR   GO; GO:0042910; F:xenobiotic transmembrane transporter activity; IEA:InterPro.
DR   CDD; cd13138; MATE_yoeA_like; 1.
DR   InterPro; IPR002528; MATE_fam.
DR   InterPro; IPR048279; MdtK-like.
DR   NCBIfam; TIGR00797; matE; 1.
DR   PANTHER; PTHR43549; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR   PANTHER; PTHR43549:SF2; MULTIDRUG RESISTANCE PROTEIN YPNP-RELATED; 1.
DR   Pfam; PF01554; MatE; 2.
DR   PIRSF; PIRSF006603; DinF; 1.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000029431};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT   TRANSMEM        29..49
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        61..83
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        104..129
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        141..165
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        177..201
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        207..230
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        256..282
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        302..319
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        339..360
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..390
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        402..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        431..455
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   469 AA;  51926 MW;  7F0DC3898C1175BB CRC64;
     MTLSHVSNKD DLNSQSKEIG GRSIRRSMIL FLIPMILSNV LQSIGQLAGS IIVGRWLGVD
     ALAAISAFFP LFFLLVSFTI GIGSGSSILI GQAYGARNEE RLKAIVGITL TFTFLLGLVL
     AILGGIFTWD ILRLIGTPEN IIAVTVHYAR ILFWSMPIMF LYFVYTTFMR GTGDSKTPFY
     FLVVSTVFNL VLLPVLVFGW LGLPRLGIYG AAYANVISTI LTFMFMLFYL RRTKHALRFD
     ASVGKHLRMD KGLLALLLRL GIPSSINMIL VSLSEIAVIA FVNHYGSDAT AAYGAVNQVA
     SYVQMPAISL GITVSIFAAQ SIGANQLGKL KQVTRTGILF NYVIGGMVIL LIYVFSKHIL
     SWFLTSSNAL NIAHSLLMIT LWSYLIFGHA QIYSATMRAS GTVLWPTLFS ILSIWCVEVP
     VAYYLSHKTS LGIHGIWIGY PAAFIVSMLL QYTYYRLSWK KKRIARLVD
//